ID A0A3Q1F8H0_9TELE Unreviewed; 762 AA.
AC A0A3Q1F8H0;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Signal peptide, CUB and EGF-like domain-containing protein 1 {ECO:0000313|Ensembl:ENSAPOP00000013253.1};
OS Acanthochromis polyacanthus (spiny chromis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Acanthochromis.
OX NCBI_TaxID=80966 {ECO:0000313|Ensembl:ENSAPOP00000013253.1, ECO:0000313|Proteomes:UP000257200};
RN [1] {ECO:0000313|Ensembl:ENSAPOP00000013253.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR AlphaFoldDB; A0A3Q1F8H0; -.
DR STRING; 80966.ENSAPOP00000013253; -.
DR Ensembl; ENSAPOT00000021361.1; ENSAPOP00000013253.1; ENSAPOG00000016507.1.
DR GeneTree; ENSGT00940000153185; -.
DR InParanoid; A0A3Q1F8H0; -.
DR Proteomes; UP000257200; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0048513; P:animal organ development; IEA:UniProt.
DR CDD; cd00041; CUB; 1.
DR CDD; cd00054; EGF_CA; 3.
DR Gene3D; 2.10.25.10; Laminin; 3.
DR Gene3D; 2.60.120.290; Spermadhesin, CUB domain; 1.
DR Gene3D; 2.10.50.10; Tumor Necrosis Factor Receptor, subunit A, domain 2; 3.
DR InterPro; IPR000859; CUB_dom.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR035914; Sperma_CUB_dom_sf.
DR InterPro; IPR011641; Tyr-kin_ephrin_A/B_rcpt-like.
DR PANTHER; PTHR24046; SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR24046:SF4; SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF00431; CUB; 1.
DR Pfam; PF07645; EGF_CA; 1.
DR Pfam; PF07699; Ephrin_rec_like; 3.
DR Pfam; PF14670; FXa_inhibition; 2.
DR SMART; SM00042; CUB; 1.
DR SMART; SM00181; EGF; 4.
DR SMART; SM00179; EGF_CA; 3.
DR SMART; SM01411; Ephrin_rec_like; 3.
DR SUPFAM; SSF57184; Growth factor receptor domain; 2.
DR SUPFAM; SSF49854; Spermadhesin, CUB domain; 1.
DR PROSITE; PS00010; ASX_HYDROXYL; 3.
DR PROSITE; PS01180; CUB; 1.
DR PROSITE; PS01186; EGF_2; 1.
DR PROSITE; PS50026; EGF_3; 2.
DR PROSITE; PS01187; EGF_CA; 2.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Reference proteome {ECO:0000313|Proteomes:UP000257200};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 90..128
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 129..169
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 572..684
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DISULFID 94..104
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 762 AA; 85264 MW; EC6826B76D4BE082 CRC64;
ILSNSQEGDF SGCKTNQMDS KEHANHKLNF NIKFTTASHF LFLSFLHSDI DECLENNGGC
DHYCRNTVGS FECSCQKGHK LLTDERTCQD IDECSFERTC DHTCINYPGS FECLCNKGYI
LYGLTHCGDI DECSINNGSC EHGCINTQGS YECVCPPGQK LHWNKKDCIE AVKCLPNGKP
VPRAQLTCTK SGGAEVCSLS CRSNALFLAD SENSYTLSCG VPVQPGKAPQ KRNATAALPT
YTLAPPIKQK ARFKIKDAKC HLRPRNKERH RDSSRQTLQG GQFPCTDDCQ VTFVNLKCDS
SKKRRRGRKS PSKEVSHITA EFEMEMKEEE VSDSCNVDCV RERMKQKLQS AMRTLRKSIN
KQQFYIQFSG TEYEVAQKPS RVPEGAETCS TGQVLRDGKC VSCAVGTFYS GEQEQCVQCP
PGTYQDTEGQ LSCEPCPSTE GQGITGAKNV SQCGGQCSAG QFSADGFRPC QPCPLGSYQP
EPGRVLCFTC GGGLMTRYEG SVSFRDCEAS QNVHLHCAPG HYYNSSTHRC IRCPAGTYQS
EFGQNYCITC PGNTTTDFDG ATNVSHCKNQ LCGGELGEYT GYIESPNYPG DYPSNVDCVW
TINPPHKRRI LIVVPEIFLP IEDECGDVLV MRKSALPTSI TTYETCQTYE RPIAFTSRSR
KLWIQFKSNE GNSGKGFQVP YVTYDEDYQQ LIEDIVRDGR LYASENHQEI LKDKKLIKAL
FDVLAHPQNY FRYTAQESKE MFPRSFIKLL RSKVTRFLRP YK
//
