ID A0A3Q1FB12_9TELE Unreviewed; 412 AA.
AC A0A3Q1FB12;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Vitronectin-like {ECO:0000313|Ensembl:ENSAPOP00000014218.1};
OS Acanthochromis polyacanthus (spiny chromis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Acanthochromis.
OX NCBI_TaxID=80966 {ECO:0000313|Ensembl:ENSAPOP00000014218.1, ECO:0000313|Proteomes:UP000257200};
RN [1] {ECO:0000313|Ensembl:ENSAPOP00000014218.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3Q1FB12; -.
DR Ensembl; ENSAPOT00000022563.1; ENSAPOP00000014218.1; ENSAPOG00000017069.1.
DR GeneTree; ENSGT00530000063751; -.
DR Proteomes; UP000257200; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0030247; F:polysaccharide binding; IEA:InterPro.
DR GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
DR GO; GO:0006955; P:immune response; IEA:InterPro.
DR CDD; cd00094; HX; 1.
DR Gene3D; 4.10.410.20; -; 1.
DR Gene3D; 2.110.10.10; Hemopexin-like domain; 1.
DR InterPro; IPR000585; Hemopexin-like_dom.
DR InterPro; IPR036375; Hemopexin-like_dom_sf.
DR InterPro; IPR018487; Hemopexin-like_repeat.
DR InterPro; IPR020436; SMB_chordata.
DR InterPro; IPR036024; Somatomedin_B-like_dom_sf.
DR InterPro; IPR001212; Somatomedin_B_dom.
DR PANTHER; PTHR22917; HEMOPEXIN DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR22917:SF3; VITRONECTIN; 1.
DR Pfam; PF00045; Hemopexin; 2.
DR Pfam; PF01033; Somatomedin_B; 1.
DR PRINTS; PR00022; SOMATOMEDINB.
DR SMART; SM00120; HX; 3.
DR SMART; SM00201; SO; 1.
DR SUPFAM; SSF50923; Hemopexin-like domain; 2.
DR SUPFAM; SSF90188; Somatomedin B domain; 1.
DR PROSITE; PS51642; HEMOPEXIN_2; 3.
DR PROSITE; PS00524; SMB_1; 1.
DR PROSITE; PS50958; SMB_2; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000257200};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..412
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018715045"
FT DOMAIN 20..61
FT /note="SMB"
FT /evidence="ECO:0000259|PROSITE:PS50958"
FT REPEAT 122..166
FT /note="Hemopexin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01011"
FT REPEAT 167..214
FT /note="Hemopexin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01011"
FT REPEAT 215..265
FT /note="Hemopexin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01011"
FT REGION 323..351
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 336..351
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 412 AA; 46623 MW; 0851D03F035779A8 CRC64;
MKPAVVLLGL VLLLDTAFAA EESCVGRCGT FSAQTKCQCD SMCVYYGSCC GDYYTICPKK
ARGDTFDENE DATETPSNVI NYTTIVMPTS DTVAPTIPAS SPSTATQAPT PLVDPDAVAC
SGRPFDAFLQ LKNSSIYAFR GEYFFELDEK SVLPGYPKLI EDVWGITGPV SAAFTRINCQ
GKSYIFKGNQ YWRFDGDVLD EDYPRQISVG FDGIPNDVDA AFAVPAPSHR GREKAYFFKD
DKYYQYEFKQ QPSHEECVQM SKSSPSMLFT QYTDLFCDNT WEDLFTGLFG SALDSHQRSP
RLISRDWHGI RSPVDAAMVG RVHLSPKPTL SSPPVRRRSS RKRRPSKKRG QKLRLSRSLF
DDLWFYDDWF DYGDYGDAVK ESTTQEYKST PVQNVYFFKR DKYYRVALKT KS
//
