ID A0A3Q1FIW3_9TELE Unreviewed; 2519 AA.
AC A0A3Q1FIW3;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Centromere protein F {ECO:0000313|Ensembl:ENSAPOP00000017871.1};
OS Acanthochromis polyacanthus (spiny chromis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Acanthochromis.
OX NCBI_TaxID=80966 {ECO:0000313|Ensembl:ENSAPOP00000017871.1, ECO:0000313|Proteomes:UP000257200};
RN [1] {ECO:0000313|Ensembl:ENSAPOP00000017871.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR STRING; 80966.ENSAPOP00000017871; -.
DR Ensembl; ENSAPOT00000027291.1; ENSAPOP00000017871.1; ENSAPOG00000021131.1.
DR GeneTree; ENSGT00730000111187; -.
DR InParanoid; A0A3Q1FIW3; -.
DR Proteomes; UP000257200; Unplaced.
DR GO; GO:0000775; C:chromosome, centromeric region; IEA:InterPro.
DR GO; GO:0070840; F:dynein complex binding; IEA:InterPro.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:InterPro.
DR Gene3D; 1.10.287.1490; -; 1.
DR Gene3D; 1.20.5.340; -; 2.
DR InterPro; IPR043513; Cenp-F.
DR InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR PANTHER; PTHR18874:SF10; CENTROMERE PROTEIN F; 1.
DR PANTHER; PTHR18874; CMF/LEK/CENP CELL DIVISION-RELATED; 1.
DR Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR Pfam; PF10473; CENP-F_leu_zip; 2.
DR SUPFAM; SSF57997; Tropomyosin; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000257200}.
FT DOMAIN 1576..1717
FT /note="Centromere protein Cenp-F leucine-rich repeat-
FT containing"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 1813..1954
FT /note="Centromere protein Cenp-F leucine-rich repeat-
FT containing"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2404..2448
FT /note="Kinetochore protein Cenp-F/LEK1 Rb protein-binding"
FT /evidence="ECO:0000259|Pfam:PF10490"
FT REGION 1..45
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 209..281
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 296..357
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1214..1239
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1407..1453
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1866..1910
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2096..2122
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2180..2211
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2223..2242
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2247..2267
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2317..2416
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2449..2519
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1488..1627
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1656..1725
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..21
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 23..45
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 209..224
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 236..252
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 264..281
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 313..357
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1407..1431
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1432..1453
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1866..1885
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1892..1910
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2096..2118
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2180..2199
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2317..2332
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2333..2355
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2356..2370
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2371..2387
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2481..2499
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2501..2519
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2519 AA; 289375 MW; 5520FDFD29BBC7BC CRC64;
METPLKRRGT SLWDAHEETP IKPSQRMSCS IAVQSPSGSS QQMEQLKTLN QELRGRVSEL
ERNLSNQEKD IRTQASKLQE LQTQLNQAHK DLTERDRDLA KTSHELSQAT DRHQKVEAKC
SSVEQKLKQV TEEMSCQRHN AEICKRALEQ KVKDQERDSQ KELAQLQSSH QALDQQLNQT
RTKLTQEIQQ SKKDCNILQA DMEKMRVQRN QMEKEMEEQK QRLLRSEQSL QANQTKEQDL
RKKMEELQKE KNSVTVQLDQ SNRRLSQLEE EKKSSEQSFK RTQGLLDDLK AKSEGQAEEL
KKLQSKLEQQ TQASAREQEH LKKTLSDAET KNDRSQNELQ KQKQETERLS NRLTVLDKES
QELKSNLTAS QNECTKLKQE HQALVEWTTE KETLINETEA VQKELSDKIN NLESSVSSLN
EANGELQKQL MCAEREKASL SSHIDSLKGE LLNKSTELEE KEHQYKELQS QFSEAGQKHT
KDLENVGIQV AQLESQVKDL ELQLQKEITR AELAERTNTE LQEEHQAACD LIRSKDQLIE
LGQTEISQLR ESLTQATAQQ EEQNARLSEE KAVLLKQCED SVSAKVEETE HIKLQMEEVQ
QELLLTKTQI SSTEQFLKVQ EQLGAELQKQ IKTLSDGEEE LKKMCKKKSE ELKQLEEDLK
DQRSQTEEKE KQFREAEAHM VSVEKQKAEL ENLVQQMKKE AEILQHSQTE TINSLLDQIS
SLEEKMAANE DAAEKLLVLK NELVVVNQSY ADLKNSLEAL EKSHSSTIEI KSNLENTLAE
KSELISALEK EIKDLTEKMS KESESHTLEI ENFINKEKSL KEQLEATKKS ISAAKVESSS
RREEIKTMKT TLSAASRGLE ERDNTIKSLK QKLNEAEAEH AKTSDLLKEK VVAMNKIKVQ
LEMLQMDLED NETAMNSFDS QVEELKGTIE LLEAQLAQNK TQMSDMEARL EESKAQVSVL
ETRLDEVQSQ NSVLETKYVT AKEELFERSC EISRLEEDSV RRNQLEETVA SLESKLSQMT
EENAKVETSF RQMVQDKDNN INQLLQQKTH LDTSLKQLMN DKEQIEAEII QINAEKKQLE
TSLEELSEQN KQLQSNIQQL TEEKLQTQVR IEEMTAEKNE AELALSQVIE EKAQFDVTLH
QIKEENADLQ SNLSALISEK CDLVANLNQA VEEKLQLESN CSQLSEENTK LQSCVNEITE
EKLKLQENIE RHQDEVTSLR EENERIQSSL LSSEQERQRL KEQLEMRDEM TEEENKERSQ
QFEERAELHH KLAVLQKELT VFKQQYDSLL ERVDQQHSLI QQLSEPQGTQ NPAEIISHME
TEDTETGAEV KGQIGVEPEN DASISTGTEP LPVKEQCVPS ELSELSHQSE TFSATELEYK
LEQEIIQEGE EEKEASAAAV EEIRTNEEEQ HLHQQVSEDS CSPRDDSENE PVICDQPSQS
SSSSEMRELE SCESSQMLDL SQYKEMICKQ ENELETLRSE FNLLSSDLEL RKELNFELEV
QVQNLEKKLQ AADEEACGAT CRLKNALEAK KSLADELTQL SEEKETLTLQ LQTAKCQLTD
VMEMLEGLEM AKGGCDEKCL QQESELKRVR SEKANLEQHI LGMESELETM QVEKTRLTDE
METQKKTSSV MEQKIDKLMT ETTQLRSELV LCSEERDELS QSLGQWREKV HTLEKTNCDT
RHLISILEDD IRAGRKEYEA LQSNTEKLKT ERQQLMEQVK LLEQAVSQQC GEREELIGHL
NQIKEDHTSA SENTESMMGK IQALEGEVCR LSQSLESSLL EKGEIASRLN STQEEVQQMR
TGIEKLQVRI ESDERKKKKM GELLKAAQRK SDSLQDRIDA LEREKEDVEQ SLEDAVLQAE
TAKAELEEER TKVEEEKKEL SEKLSELSAT LDNLRSEKEH MERELETKNR EIEELKAAKE
ELERGLEKAE VDRREEEEKQ KYRVEELEKG IKEAERQIRR VDDLQAQLEA SRQREILLKE
KLAENEQLVA EKEKLHSTLL SLQQEGDNLR CTLTSVEGEK ERLDQERSVL ADEKEKLQSG
LSLIEKEKCD LQQNLSSLKQ EKERIEEEKQ KLEAEKQELQ SSLSLVEEEK KKLSLTVSSL
EQEKQQTEEE KEKLRQEQES LQTAVASVEK ELETNKLSIS QLKEQVSELT SHAARLSKER
DSALSKISLW MKTCKQLEQE KQTMLNSSGD KSSEEVQPEV TQLRMEAETR KKDIEDLKKA
LEKKTTEAEE RLVESQEKNK EFEQLMATLD GKKKEMEDKE RKLEEMKSEL DELNNVLDEK
SKEADDSMDK YCSLMVKVHK LEETNDALKT RLEQITATQR TEAANGLASS TDNRRRSGRR
SSSKHQEEKM NDNTENVDPQ RSPQGSSSGK RGHRDISDKD SAQEALHNLT KKIKANAMTT
PRPRAEQDDE EFRPEGLPEL VQKGFADIPL GEASPFIIRR TTAKRCSPRL AARQALHTSS
PDGKVLSPFA GPSTDGSNKK RFSPSSEEKP VHRLLKTPQQ KDKQPLGQQT QQGDNCHIQ
//
