ID A0A3Q1FJ25_9TELE Unreviewed; 439 AA.
AC A0A3Q1FJ25;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Purple acid phosphatase {ECO:0000256|RuleBase:RU361203};
DE EC=3.1.3.2 {ECO:0000256|RuleBase:RU361203};
OS Acanthochromis polyacanthus (spiny chromis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Acanthochromis.
OX NCBI_TaxID=80966 {ECO:0000313|Ensembl:ENSAPOP00000016389.1, ECO:0000313|Proteomes:UP000257200};
RN [1] {ECO:0000313|Ensembl:ENSAPOP00000016389.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a phosphate monoester + H2O = an alcohol + phosphate;
CC Xref=Rhea:RHEA:15017, ChEBI:CHEBI:15377, ChEBI:CHEBI:30879,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:67140; EC=3.1.3.2;
CC Evidence={ECO:0000256|RuleBase:RU361203};
CC -!- SIMILARITY: Belongs to the metallophosphoesterase superfamily. Purple
CC acid phosphatase family. {ECO:0000256|RuleBase:RU361203}.
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DR AlphaFoldDB; A0A3Q1FJ25; -.
DR STRING; 80966.ENSAPOP00000016389; -.
DR Ensembl; ENSAPOT00000025388.1; ENSAPOP00000016389.1; ENSAPOG00000019497.1.
DR GeneTree; ENSGT00390000015485; -.
DR InParanoid; A0A3Q1FJ25; -.
DR OrthoDB; 203742at2759; -.
DR Proteomes; UP000257200; Unplaced.
DR GO; GO:0003993; F:acid phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd00839; MPP_PAPs; 1.
DR Gene3D; 3.60.21.10; -; 1.
DR Gene3D; 2.60.40.380; Purple acid phosphatase-like, N-terminal; 1.
DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR InterPro; IPR041792; MPP_PAP.
DR InterPro; IPR008963; Purple_acid_Pase-like_N.
DR InterPro; IPR015914; Purple_acid_Pase_N.
DR InterPro; IPR025733; Purple_acid_PPase_C_dom.
DR PANTHER; PTHR45867:SF3; ACID PHOSPHATASE TYPE 7; 1.
DR PANTHER; PTHR45867; PURPLE ACID PHOSPHATASE; 1.
DR Pfam; PF00149; Metallophos; 1.
DR Pfam; PF14008; Metallophos_C; 1.
DR Pfam; PF16656; Pur_ac_phosph_N; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
DR SUPFAM; SSF49363; Purple acid phosphatase, N-terminal domain; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Hydrolase {ECO:0000256|RuleBase:RU361203};
KW Reference proteome {ECO:0000313|Proteomes:UP000257200};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|RuleBase:RU361203}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|RuleBase:RU361203"
FT CHAIN 21..439
FT /note="Purple acid phosphatase"
FT /evidence="ECO:0000256|RuleBase:RU361203"
FT /id="PRO_5018379130"
FT DOMAIN 28..120
FT /note="Purple acid phosphatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16656"
FT DOMAIN 131..338
FT /note="Calcineurin-like phosphoesterase"
FT /evidence="ECO:0000259|Pfam:PF00149"
FT DOMAIN 363..425
FT /note="Iron/zinc purple acid phosphatase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14008"
SQ SEQUENCE 439 AA; 50398 MW; 669D8AB3AB544ACE CRC64;
MLPLYAACIL LNLAPLLVLG VPPIWTQPEQ VHLSYAGVPG SMVVTWTTFN KTESKVEYGL
LGGRLFEMSA KGNATLFVDS GEEKRKMFIH RVTLTGLKPA ANYVYHCGSD EGWSDVFLFT
ALNDSSSFSP RFALYGDLGN ENPQSLARLQ KETQLGMYDV ILHIGDFAYD MHEDNARIGD
EFMRQIQSIA AYVPYMTCPG NHESAYNFSN YRNRFSMPGQ TESLWYSWNL GSAHIISLST
EVYFYLEFGQ ELLFKQYEWL RNDLEEANRP ENRAVHPWII TMGHRPMYCS DDDQDDCTKF
DSYVRLGRND TKPPAPGLED LFYRYGVDVE LWAHEHTYER LWPVYGDKVY NGSRERPYVN
PKAPVHIITG SAGCRERTDR FNPNPKEWSA FRSTDYGYSR MQVVNGTHLY LEQVSDDQSG
KVIDSIWVVK EKHGFSAWL
//
