ID   A0A3Q1FJ42_9TELE        Unreviewed;       407 AA.
AC   A0A3Q1FJ42;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Failed axon connections homolog {ECO:0000313|Ensembl:ENSAPOP00000015882.1};
GN   Name=FAXC {ECO:0000313|Ensembl:ENSAPOP00000015882.1};
OS   Acanthochromis polyacanthus (spiny chromis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Acanthochromis.
OX   NCBI_TaxID=80966 {ECO:0000313|Ensembl:ENSAPOP00000015882.1, ECO:0000313|Proteomes:UP000257200};
RN   [1] {ECO:0000313|Ensembl:ENSAPOP00000015882.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the FAX family. {ECO:0000256|ARBA:ARBA00006475}.
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DR   AlphaFoldDB; A0A3Q1FJ42; -.
DR   STRING; 80966.ENSAPOP00000015882; -.
DR   Ensembl; ENSAPOT00000024705.1; ENSAPOP00000015882.1; ENSAPOG00000018955.1.
DR   GeneTree; ENSGT00950000182919; -.
DR   InParanoid; A0A3Q1FJ42; -.
DR   OrthoDB; 3684737at2759; -.
DR   Proteomes; UP000257200; Unplaced.
DR   CDD; cd03193; GST_C_Metaxin; 1.
DR   CDD; cd03080; GST_N_Metaxin_like; 1.
DR   Gene3D; 1.20.1050.10; -; 1.
DR   Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR   InterPro; IPR026928; FAX/IsoI-like.
DR   InterPro; IPR045796; FAXC_N.
DR   InterPro; IPR036282; Glutathione-S-Trfase_C_sf.
DR   InterPro; IPR033468; Metaxin_GST.
DR   InterPro; IPR012336; Thioredoxin-like_fold.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   PANTHER; PTHR12289:SF76; FAILED AXON CONNECTIONS HOMOLOG; 1.
DR   PANTHER; PTHR12289; METAXIN RELATED; 1.
DR   Pfam; PF19333; FAXC_N; 1.
DR   Pfam; PF17171; GST_C_6; 1.
DR   Pfam; PF17172; GST_N_4; 1.
DR   SFLD; SFLDG01180; SUF1; 1.
DR   SFLD; SFLDG01200; SUF1.1; 1.
DR   SUPFAM; SSF47616; GST C-terminal domain-like; 1.
DR   SUPFAM; SSF52833; Thioredoxin-like; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000257200}.
FT   DOMAIN          1..103
FT                   /note="Failed axon connections homolog N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF19333"
FT   DOMAIN          114..207
FT                   /note="Thioredoxin-like fold"
FT                   /evidence="ECO:0000259|Pfam:PF17172"
FT   DOMAIN          259..321
FT                   /note="Metaxin glutathione S-transferase"
FT                   /evidence="ECO:0000259|Pfam:PF17171"
FT   REGION          362..407
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        389..407
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   407 AA;  46174 MW;  3E5F4354DAEBEEE9 CRC64;
     MYWRVGFAWL RSCAVDLGQN QSSSSGLPGS DERLLFGCIV ACPLQDCGGI MSALGSDSWW
     RKTLYLTGGA LLAAAAYLLH ELLAIRKEEE LDSKDAIILH QFSRPKSGAP SLSPFCLKME
     TYLRMVDLPY QNYFDGKLSP QGKMPWIEYN QEQVFGSEFI IDFLEERLGV SLNRSLTPQE
     KAVSRAVTKM VEEHFYWTVA YCQWVDNLEE TQKMLSVSGP LSDLLRWILS HLTGGIVKRE
     MYGHGIGRFS KEEVYALMEK DMRTLATLLG DKKYLMGSKL STVDAAVFSH LAPAMWTLPG
     SRPEQLIKGE LINLAMYCER IRRRFWPEWF VDLEDFRYTD TTESVNSASK LPDLGLYSRT
     DTFHDDTHSH TSQTPRDPPS PDSDPTGHSL YDSDMDTECS DTDQLKC
//