ID   A0A3Q1FJC3_9TELE        Unreviewed;       808 AA.
AC   A0A3Q1FJC3;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Cadherin-6-like {ECO:0000313|Ensembl:ENSAPOP00000015957.1};
OS   Acanthochromis polyacanthus (spiny chromis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Acanthochromis.
OX   NCBI_TaxID=80966 {ECO:0000313|Ensembl:ENSAPOP00000015957.1, ECO:0000313|Proteomes:UP000257200};
RN   [1] {ECO:0000313|Ensembl:ENSAPOP00000015957.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- FUNCTION: Cadherins are calcium-dependent cell adhesion proteins.
CC       {ECO:0000256|RuleBase:RU004357}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004251,
CC       ECO:0000256|RuleBase:RU003318}; Single-pass type I membrane protein
CC       {ECO:0000256|ARBA:ARBA00004251, ECO:0000256|RuleBase:RU003318}.
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DR   STRING; 80966.ENSAPOP00000015957; -.
DR   Ensembl; ENSAPOT00000024837.1; ENSAPOP00000015957.1; ENSAPOG00000019059.1.
DR   Ensembl; ENSAPOT00000033450.1; ENSAPOP00000031624.1; ENSAPOG00000019059.1.
DR   GeneTree; ENSGT00940000154673; -.
DR   OrthoDB; 3667774at2759; -.
DR   Proteomes; UP000257200; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR   GO; GO:0048890; P:lateral line ganglion development; IEA:Ensembl.
DR   GO; GO:0048793; P:pronephros development; IEA:Ensembl.
DR   GO; GO:0060042; P:retina morphogenesis in camera-type eye; IEA:Ensembl.
DR   CDD; cd11304; Cadherin_repeat; 5.
DR   Gene3D; 2.60.40.60; Cadherins; 5.
DR   Gene3D; 4.10.900.10; TCF3-CBD (Catenin binding domain); 1.
DR   InterPro; IPR039808; Cadherin.
DR   InterPro; IPR002126; Cadherin-like_dom.
DR   InterPro; IPR015919; Cadherin-like_sf.
DR   InterPro; IPR020894; Cadherin_CS.
DR   InterPro; IPR000233; Cadherin_Y-type_LIR.
DR   InterPro; IPR027397; Catenin-bd_sf.
DR   PANTHER; PTHR24027:SF428; CADHERIN 6; 1.
DR   PANTHER; PTHR24027; CADHERIN-23; 1.
DR   Pfam; PF01049; CADH_Y-type_LIR; 1.
DR   Pfam; PF00028; Cadherin; 5.
DR   PRINTS; PR00205; CADHERIN.
DR   SMART; SM00112; CA; 5.
DR   SUPFAM; SSF49313; Cadherin-like; 5.
DR   PROSITE; PS00232; CADHERIN_1; 2.
DR   PROSITE; PS50268; CADHERIN_2; 5.
PE   4: Predicted;
KW   Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW   ProRule:PRU00043};
KW   Cell adhesion {ECO:0000256|ARBA:ARBA00022889,
KW   ECO:0000256|RuleBase:RU003318};
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000257200};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU003318};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           20..808
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5041077214"
FT   TRANSMEM        614..635
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          77..157
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          158..268
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          269..382
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          383..487
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          487..610
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
SQ   SEQUENCE   808 AA;  88978 MW;  97611DC579D680D5 CRC64;
     MRTILVGVVW LCLGLFLDAM SLNGRRMDAA LDGEGVGAAV KGEKLLKRVR RGWMWNQFFL
     QEEYTGSDNQ YIGKLQSDQD HGNGLVKYIL SGEGAGTIFV LDENNGNLHA TRRLDREEKS
     SYILRATVIN KRTGQKLEPE TEFTVKLHDI NDNEPHFSKE VYTGSVPERS DIGTSVMQVT
     ATDADDSMYG NSAKLVYSIS QGHPYFSVDP NTGVIRTALG PGDMDREQRE HYQVVIEAKD
     MAGQRGGLTG TTVVNITLTD VNDNPPRFTQ SIYQFRVPES SKSGSPVGRI QATDRDIGRN
     AEMYFTIVSG DGMDMFDIST DKDTQEGVIT VSKPLDFEKK PSYTVEIQVQ NTQVDPRFMS
     SGSKDMATVR IAVEDVDEPP LFDKASYLME VKEDAGVGVA VGSVSAVDPD GARSIVKYSI
     DRRTDMDHVF QIHPGNGSVF LLRSLDREEA AWHNITIIAT EYSNPRQSSH VPVYIRLLDI
     NDNAPTFADT YETFVCEKTK AGQRIKTVSA IDADEPSTGH KFFFSLAPEV PHRSNFTVRD
     NGDNTAGILT RRASYSRLHQ SVYLVPVVIT DGDYPMQSST GTLTVKVCTC DREGNMELCS
     AEALSSSPGL STGALIAILL CAIILLMIVV LFTALKRQRK QEPLIISKED VRDNVVSYND
     EGGGEEDTQA FDIGALRHPD AAAALEESAK QRRDIIPTDT LLYPPQRRPA PAASGLIMPP
     VNMASRDNGD VREFINQRVL ENDCNPTAPP YDSLATYAYE GAGSVAESLS SLGSASSEAE
     QDYHYLSDWG PRFRKLADLY GAEDSDFS
//