ID   A0A3Q1FME7_9TELE        Unreviewed;       832 AA.
AC   A0A3Q1FME7;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Cadherin 26 {ECO:0000313|Ensembl:ENSAPOP00000008005.1};
OS   Acanthochromis polyacanthus (spiny chromis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Acanthochromis.
OX   NCBI_TaxID=80966 {ECO:0000313|Ensembl:ENSAPOP00000008005.1, ECO:0000313|Proteomes:UP000257200};
RN   [1] {ECO:0000313|Ensembl:ENSAPOP00000008005.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- FUNCTION: Cadherins are calcium-dependent cell adhesion proteins.
CC       {ECO:0000256|RuleBase:RU004357}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004251,
CC       ECO:0000256|RuleBase:RU003318}; Single-pass type I membrane protein
CC       {ECO:0000256|ARBA:ARBA00004251, ECO:0000256|RuleBase:RU003318}.
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DR   AlphaFoldDB; A0A3Q1FME7; -.
DR   STRING; 80966.ENSAPOP00000008005; -.
DR   Ensembl; ENSAPOT00000003974.1; ENSAPOP00000008005.1; ENSAPOG00000010127.1.
DR   GeneTree; ENSGT00940000161589; -.
DR   InParanoid; A0A3Q1FME7; -.
DR   OrthoDB; 5353267at2759; -.
DR   Proteomes; UP000257200; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR   CDD; cd11304; Cadherin_repeat; 3.
DR   Gene3D; 2.60.40.60; Cadherins; 5.
DR   Gene3D; 4.10.900.10; TCF3-CBD (Catenin binding domain); 1.
DR   InterPro; IPR039808; Cadherin.
DR   InterPro; IPR002126; Cadherin-like_dom.
DR   InterPro; IPR015919; Cadherin-like_sf.
DR   InterPro; IPR020894; Cadherin_CS.
DR   InterPro; IPR000233; Cadherin_Y-type_LIR.
DR   InterPro; IPR027397; Catenin-bd_sf.
DR   PANTHER; PTHR24027; CADHERIN-23; 1.
DR   PANTHER; PTHR24027:SF78; CADHERIN-LIKE PROTEIN 26; 1.
DR   Pfam; PF01049; CADH_Y-type_LIR; 1.
DR   Pfam; PF00028; Cadherin; 3.
DR   PRINTS; PR00205; CADHERIN.
DR   PRINTS; PR01820; DESMOCOLLIN.
DR   SMART; SM00112; CA; 4.
DR   SUPFAM; SSF49313; Cadherin-like; 5.
DR   PROSITE; PS00232; CADHERIN_1; 2.
DR   PROSITE; PS50268; CADHERIN_2; 5.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   4: Predicted;
KW   Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW   ProRule:PRU00043};
KW   Cell adhesion {ECO:0000256|ARBA:ARBA00022889,
KW   ECO:0000256|RuleBase:RU003318};
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000257200};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU003318};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           21..832
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5018589134"
FT   TRANSMEM        597..618
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          47..143
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          144..254
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          272..379
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          390..485
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          502..591
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
SQ   SEQUENCE   832 AA;  94269 MW;  BE51C22756B7E838 CRC64;
     MRIIFLLFLV AFAALGACHG SEHNRLAKRD VLLRSKRRWV LSTIELEEEK KGTYPMIISQ
     MFNDKTEGKN FKFKISGEGV DTNIFSINEK TGIVYARRAV DREEKDTYHI KFDVLEKETN
     AQIDKELSFD VEIKDINDNP PVFFSSKIVA DVEENKEEGY LPVQVQASDR DQKNTDNSKF
     DFTVLSQFPK EPKIDVYQLD ERMGQLTFKG CFDYDKAKRY KIIVQAKDRG TPPLSSTCVV
     FLNIHDRNTH LPTFNQTEYH AQEDEMVTKN DILRIKVEDK DTPNTDGWRA KYFFIKGNED
     EMFDITTDPK TNEGIVSIVK KKNFDLTTVL DLEVGVKNVE ELFVCKNKSA DSKATSVSPT
     PNSVRMTVKM VDANDPPDFG RATSDVYHKE EEMPGKVLFT PKVNDVDSNG FRYVLLDDPA
     DWVAIDPETG TLKSTKKMDR ESPFVDKHNV YKVVIAAIDD GEPPATGTCT VQIHLRDIND
     NTPKLVNNSL ILCGNKAKKI KVSAKDLDQT PYSGPFSFSL AGDKSLKEQW KLDPNFGMEV
     GLVSLKTLPY GNYSVPFKIL DQQNIPGEDT LEVMVCDCEK GDVCRDKKPL SASFGDAGIG
     LLIAGLLLFL LLLLIFMCEC GKKTFEYMEQ DEGNQTLIKY NQEGGGSACK AEPTLLLTPT
     KGISVVDGIK QGTIRMTEMA PVMTQDVDRF NTSYTMQMNS NMTSMGMHPR DSVRSHEGQM
     MNKYSTWTTN RMNTYQSNSS HYMRSISLRS NQRIADHIDR RLYMIDGMPV DYPVYQPYKY
     AYEGQGSKCQ SLDELSVTNL SDDLQFLDDL GPKFKTLGDI CQKKIKEKNT QL
//