ID A0A3Q1FPE6_9TELE Unreviewed; 670 AA.
AC A0A3Q1FPE6;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=SH3 domain-binding protein 1-like {ECO:0000313|Ensembl:ENSAPOP00000019068.1};
OS Acanthochromis polyacanthus (spiny chromis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Acanthochromis.
OX NCBI_TaxID=80966 {ECO:0000313|Ensembl:ENSAPOP00000019068.1, ECO:0000313|Proteomes:UP000257200};
RN [1] {ECO:0000313|Ensembl:ENSAPOP00000019068.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3Q1FPE6; -.
DR Ensembl; ENSAPOT00000028829.1; ENSAPOP00000019068.1; ENSAPOG00000022443.1.
DR GeneTree; ENSGT00940000158369; -.
DR Proteomes; UP000257200; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR004148; BAR_dom.
DR InterPro; IPR047165; RHG17/44/SH3BP1-like.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR14130; 3BP-1 RELATED RHOGAP; 1.
DR PANTHER; PTHR14130:SF12; BARGIN-RELATED; 1.
DR Pfam; PF03114; BAR; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS51021; BAR; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000257200}.
FT DOMAIN 1..192
FT /note="BAR"
FT /evidence="ECO:0000259|PROSITE:PS51021"
FT DOMAIN 204..396
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 104..123
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 440..460
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 473..670
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 473..503
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 509..523
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 532..551
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 604..662
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 670 AA; 73669 MW; 70274BB9B3EB1DC8 CRC64;
MSESTLLVAE KCPMCFCPQK KLPLMLLSIS MAESLKDFDA ESSIRRVLEM CCFMEKMLAN
MLADFEVKVE KEVLEPLNKL SEDDLPEILK NKKQFAKLRT DWNNARNRSQ ASTGPQAKQD
GLREEVEEAW RKLESIKDQY SADLYHFATK EDDYANYFIR LLELQAEYHK SSHEFLDKNI
SELKENHSQK GQPLSTSNRK VYGEPLLSHL TQSEKEIAAP IQECIHMLLR TGMREEGLFR
LAAAASVVKR LKTCLDQGTV DHSEFSMDPH AVAGALKCYL RELPEPLMTF ELYSDWFKAA
GEKDMQEKLE QFRMLLKKLP PENYNNLRYL VQFLSLLSEH QAVNKMTPSN IAIVLGPNLL
WPKAEGEAAL FDMASASSVQ VVTVIEPLIQ YSSSLFPEAI SFEVPDLPEV PDVPLPAPGT
QSLFLDKEKL KRTVSSASST ASSCSSYHLP LSKTNSTASQ DSGGFFLVKS GSVSSRTGTT
TWGSPTAETA APSHQNTASS LDPGPALASI PSTENSSTAN QKPAPPLRAG ASAANSGQTK
SPTQKQCSDQ GQLEPILEAP PDSPKAFVKI TSPYKPKRTF NPGKPNEASE PPTVHYTKPK
TLAPPRSQAP PPPSTAPEVS DSRPQPTPAP RAQPPTSKKP PPRKPGLRAP NCPPPLPPPS
QAKEVPSIAQ
//
