ID   A0A3Q1FSX7_9TELE        Unreviewed;       791 AA.
AC   A0A3Q1FSX7;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Rho GTPase-activating protein 6-like {ECO:0000313|Ensembl:ENSAPOP00000018727.1};
GN   Name=ARHGAP6 {ECO:0000313|Ensembl:ENSAPOP00000018727.1};
OS   Acanthochromis polyacanthus (spiny chromis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Acanthochromis.
OX   NCBI_TaxID=80966 {ECO:0000313|Ensembl:ENSAPOP00000018727.1, ECO:0000313|Proteomes:UP000257200};
RN   [1] {ECO:0000313|Ensembl:ENSAPOP00000018727.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3Q1FSX7; -.
DR   STRING; 80966.ENSAPOP00000018727; -.
DR   Ensembl; ENSAPOT00000028391.1; ENSAPOP00000018727.1; ENSAPOG00000022096.1.
DR   GeneTree; ENSGT00940000153904; -.
DR   InParanoid; A0A3Q1FSX7; -.
DR   OrthoDB; 5482290at2759; -.
DR   Proteomes; UP000257200; Unplaced.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd04376; RhoGAP_ARHGAP6; 1.
DR   Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR   InterPro; IPR041852; ARHGAP6_RhoGAP.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR037863; RHOGAP6/36.
DR   InterPro; IPR000198; RhoGAP_dom.
DR   PANTHER; PTHR12635:SF14; RHO GTPASE-ACTIVATING PROTEIN 6; 1.
DR   PANTHER; PTHR12635; RHO-GTPASE-ACTIVATING PROTEIN 6 FAMILY MEMBER; 1.
DR   Pfam; PF00620; RhoGAP; 1.
DR   SMART; SM00324; RhoGAP; 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   PROSITE; PS50238; RHOGAP; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW   Reference proteome {ECO:0000313|Proteomes:UP000257200}.
FT   DOMAIN          256..457
FT                   /note="Rho-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50238"
FT   REGION          107..134
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          184..215
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          547..580
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          611..683
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          715..771
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        114..128
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        184..206
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        547..565
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        566..580
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        611..635
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        667..683
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        715..754
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   791 AA;  88357 MW;  7C155EB49E8AABA7 CRC64;
     MSAQGLLSSV FSCSLSPKSI SKRRLRQTRS LDSALMLHYG TEAEETSCKG DFTWNSVSGR
     SVGLKPVPLQ SLSELERVRL QDVAFRRLLR GHDLGCHVSI PKYGHKHKKS LRRKLDSLSK
     EKSKDRETTP QAFGIPLSHV ISNDRVHKLR HDHPREEHSD PTELMLSFLH LNSSFKRVNK
     ELSSSNSSLS STSETLNESP LPSTPDTAPR TRRRGGVSVD CITDLDDNQS RLLEALQLSL
     PEEAAGNRKK HHDKKLSLNP IYRQVPRIVD LCCQHLEQYG LQTVGIFRVG SSKKRVRQLR
     EEFDQGWEVH MDEEHSVHDV AALLKEFLRD MPESLLTREL YTAFINTMML DYSDQESAIQ
     LLIYLLPPCN SDTLQRLLGL LSTVSAHAED SLDNEGQQVT GNKMTSLNLA TVFGPNLLHK
     QKNSDKEFAV ESFARAEEST AIIGVVQRMI DAYDTLFMVP ADLQNEVLMS LLETDPDVVD
     YLLRRKASQC SESGLLRPEE SFPLTERCLS NDSLKASSGE VSPYDNNSPV LSNRLLCKYP
     EDSDLRSERF TRSSDKYKLR DHSKDGSGST SPTLSTDKEL STDSFWDTWQ ELLSKDLTGH
     HITGSLGDAS ECDSYGSSEG LSSHQGNNKL PVRPTQTSLD VLECRPHLPV TRSSSGPHDQ
     REQRQPETSL HQSLSSQSAA ISSDNLAQRT GCAACPLFKV RTDSSSPFHC SGPLRDTHIS
     HSTPSLFTHK PDPQTPQQSQ QSSAVQTGDT TDASGPGEEK SPDPSNWQTE RWHIWQILSK
     ENPEALTETL V
//