ID A0A3Q1FTE3_9TELE Unreviewed; 1012 AA.
AC A0A3Q1FTE3;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=FERM domain containing 4A {ECO:0000313|Ensembl:ENSAPOP00000018892.1};
OS Acanthochromis polyacanthus (spiny chromis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Acanthochromis.
OX NCBI_TaxID=80966 {ECO:0000313|Ensembl:ENSAPOP00000018892.1, ECO:0000313|Proteomes:UP000257200};
RN [1] {ECO:0000313|Ensembl:ENSAPOP00000018892.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3Q1FTE3; -.
DR Ensembl; ENSAPOT00000028617.1; ENSAPOP00000018892.1; ENSAPOG00000022522.1.
DR GeneTree; ENSGT01020000230354; -.
DR Proteomes; UP000257200; Unplaced.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0090162; P:establishment of epithelial cell polarity; IEA:InterPro.
DR CDD; cd14473; FERM_B-lobe; 1.
DR CDD; cd13191; FERM_C_FRMD4A_FRMD4B; 1.
DR CDD; cd17199; FERM_F1_FRMD4A; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR021774; CUPID.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR019747; FERM_CS.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR018979; FERM_N.
DR InterPro; IPR018980; FERM_PH-like_C.
DR InterPro; IPR047176; FRMD4A/B.
DR InterPro; IPR041785; FRMD4A/B_FERM_C.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR46079; FERM DOMAIN-CONTAINING PROTEIN 4; 1.
DR PANTHER; PTHR46079:SF3; FERM DOMAIN-CONTAINING PROTEIN 4A; 1.
DR Pfam; PF11819; CUPID; 1.
DR Pfam; PF09380; FERM_C; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF09379; FERM_N; 1.
DR SMART; SM00295; B41; 1.
DR SMART; SM01196; FERM_C; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS00660; FERM_1; 1.
DR PROSITE; PS00661; FERM_2; 1.
DR PROSITE; PS50057; FERM_3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000257200}.
FT DOMAIN 5..289
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT REGION 332..352
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 511..809
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 863..900
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 913..1012
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 332..351
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 537..554
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 563..577
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 603..682
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 711..750
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 764..784
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 914..942
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 955..1012
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1012 AA; 111999 MW; CE0C14309F721C4C CRC64;
MTEGRRCQVH LLDDRKLELL VQPKLMAKDL LDLVASHFNL KEKEYFGIAY TDETGHFSWL
QLDRRVLEHE FPKKSGPIVL YFCVRFYIES ISYLKDNATI ELFFLNAKSI IYKELIEVDS
DIVFELASYI LVDQVLWFFF PPKLSTQPAE CYRVIEHYKK LSGQSRGQAI VNYMSIVESL
PTYGVHYYAV KDKQGIPWWL GLSYKGIFQY DHQDKVKPRK VFQWRQLENL YFREKKFSVE
VHDPRRASVT RRTFGHSGIA VHTWYACPAL IKSIWAMAIS QHQFYLDRKQ SKSKIHAARS
LSEIAIDLTE TGTLKTSKLA NMGSKGKIIS GSSGSLLSSG SQESDSSQTA KKDMLAALRA
RQEALEETLR QRLEELKSIC IREAELTGKL PKEYPLDPGE EPPTVRRKIG TAFKLDEQKI
LPKGEEEELE RLEREFAIQS QITEAARRLA SDPHVSSKKL KKQRKTSYLN ALKKLQEIEN
SINEYRVRSG KKPTQRASLI IEEANMCSED SSLSDALVLD DDDPQVTGTP TFSPVASPHK
GLPPRPPSHS RPPPPQSLDG LRHLHYTRSD YDKSPIKPKM WSESSLDEPY EKVKKRSSHS
SHRRFPSSGS AEAGGSNSLQ SSPIRSLPHW NSQSSMPSTP DLRTRNPHYI HSTRSVDISP
TRLHSLSQHF RNRSSSLESQ GKLLVSDPDA HPHTLGSPDF FLGPGRSSNG SDPLDDCSSC
TSQSSSEHYY PSGGPPGSNP NYSTLGEDSP SKARQRQRQR HRSAGHLGSS NSGSMPNLAA
KNGSGGGSSG GGMGGGHHGV YLHSQSQPSS QYRIKEYPLY VEGSPNPVVV RSLESDQEGH
YSVKAQFKTS SSYTAGGLYK EAWGGEEGGE GSGRLTPSRS QIVRTPSLGR EGGGGGGGRA
AVSEELRCWY QRSSGSLKER SHSHSGSTSS ETGSQQGTLG HGRGSRVGTL VKGSPAASPH
SQRSMTPSSE HAATPTPPCS PQHILNWQSG GTADSSPTED VCQSPPQPNS DA
//
