ID A0A3Q1FUC3_9TELE Unreviewed; 749 AA.
AC A0A3Q1FUC3;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Erythrocyte membrane protein band 4.1 like 3 {ECO:0000313|Ensembl:ENSAPOP00000020059.1};
GN Name=EPB41L3 {ECO:0000313|Ensembl:ENSAPOP00000020059.1};
OS Acanthochromis polyacanthus (spiny chromis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Acanthochromis.
OX NCBI_TaxID=80966 {ECO:0000313|Ensembl:ENSAPOP00000020059.1, ECO:0000313|Proteomes:UP000257200};
RN [1] {ECO:0000313|Ensembl:ENSAPOP00000020059.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3Q1FUC3; -.
DR Ensembl; ENSAPOT00000035096.1; ENSAPOP00000020059.1; ENSAPOG00000023793.1.
DR GeneTree; ENSGT00940000157047; -.
DR Proteomes; UP000257200; Unplaced.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR GO; GO:0030866; P:cortical actin cytoskeleton organization; IEA:InterPro.
DR CDD; cd14473; FERM_B-lobe; 1.
DR CDD; cd13184; FERM_C_4_1_family; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR008379; Band_4.1_C.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR000798; Ez/rad/moesin-like.
DR InterPro; IPR014847; FA.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR019747; FERM_CS.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR018979; FERM_N.
DR InterPro; IPR018980; FERM_PH-like_C.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR007477; SAB_dom.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR23280; 4.1 G PROTEIN; 1.
DR PANTHER; PTHR23280:SF20; BAND 4.1-LIKE PROTEIN 3; 1.
DR Pfam; PF05902; 4_1_CTD; 1.
DR Pfam; PF08736; FA; 1.
DR Pfam; PF09380; FERM_C; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF09379; FERM_N; 1.
DR Pfam; PF04382; SAB; 1.
DR PIRSF; PIRSF002304; Membrane_skeletal_4_1; 2.
DR PRINTS; PR00935; BAND41.
DR PRINTS; PR00661; ERMFAMILY.
DR SMART; SM00295; B41; 1.
DR SMART; SM01195; FA; 1.
DR SMART; SM01196; FERM_C; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS00660; FERM_1; 1.
DR PROSITE; PS00661; FERM_2; 1.
DR PROSITE; PS50057; FERM_3; 1.
PE 4: Predicted;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Reference proteome {ECO:0000313|Proteomes:UP000257200}.
FT DOMAIN 93..389
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT REGION 1..82
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 477..639
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 24..50
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 59..74
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 477..495
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 526..540
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 541..580
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 623..639
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 749 AA; 83589 MW; 1F4B3BF031468342 CRC64;
MTTESGADSE AKQLQENKET QKGKGKAASQ PSQAAAEPTS PQNQPEQLPA AAGHSTPARK
EQEQAEEDLV SHRSSTSRLS RSPLRGVKKV KIMQCKITLL DGSDYTLNVE KRVKGHVLFD
KVCDHLNLLE KDYFGITYRD MENQKNWLDP SKELKKQIRT GPWNFAFNVK FYPPDPSQLT
EDITRYYLCL QLRDDVVSGR LPCSFATHTV LGSYTVQSEL GDYDPEELGS DYISELRFAP
NQTKELEEKV MELHKTYKGM TPAEAEMHFL ENAKKLSMYG VDLHHAKLVG SLYESLAPAE
GEDSEGVEIM LGVCASGLLI YRDRLRINRF AWPKILKISY KRNNFYIKIR PGEFEQFEST
IGFKLPNHRA AKRLWKVCVE HHTFFRLVSP EAPPKKFLSL GSKFRYSGRT QAQTRRASSQ
IIRPAPFFER SSSKRYNMSR SLDGAPIMEN HETLMKDNAV AKVITKGDII TAVTTEKKVE
EDKSEQEDTH KDAAETPEAV ATTPLRQDTK TDSEQTDFAF DGEMTATESE ADEDSEMQTQ
DTEPSAEVVK HQTNISELKR SFLETGGSTP GLTEWEKRLS SSPVHSPRAH EAPMIEPLEP
QDTNDEQPTG DEAKEEVNAK ATESTLGWVS SSQKASPDQQ EKAVVAVETE AESAKLTAPT
SPDVVEVATK DMPVVHTETK TITYEAAEVD TNGDADPGVL LSAQTITSET TSTTTTTHIT
KTVKGGISET RIEKRIVITG DADIDHDEE
//
