ID   A0A3Q1FUS7_9TELE        Unreviewed;       927 AA.
AC   A0A3Q1FUS7;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=EMAP like 3 {ECO:0000313|Ensembl:ENSAPOP00000010270.1};
GN   Name=EML3 {ECO:0000313|Ensembl:ENSAPOP00000010270.1};
OS   Acanthochromis polyacanthus (spiny chromis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Acanthochromis.
OX   NCBI_TaxID=80966 {ECO:0000313|Ensembl:ENSAPOP00000010270.1, ECO:0000313|Proteomes:UP000257200};
RN   [1] {ECO:0000313|Ensembl:ENSAPOP00000010270.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the WD repeat EMAP family.
CC       {ECO:0000256|ARBA:ARBA00006489}.
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DR   AlphaFoldDB; A0A3Q1FUS7; -.
DR   STRING; 80966.ENSAPOP00000010270; -.
DR   Ensembl; ENSAPOT00000000129.1; ENSAPOP00000010270.1; ENSAPOG00000012679.1.
DR   GeneTree; ENSGT00940000159589; -.
DR   InParanoid; A0A3Q1FUS7; -.
DR   Proteomes; UP000257200; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR   InterPro; IPR005108; HELP.
DR   InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR001680; WD40_rpt.
DR   PANTHER; PTHR13720:SF15; ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 3; 1.
DR   PANTHER; PTHR13720; WD-40 REPEAT PROTEIN; 1.
DR   Pfam; PF03451; HELP; 1.
DR   Pfam; PF00400; WD40; 4.
DR   SMART; SM00320; WD40; 7.
DR   SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 2.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000257200};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT   TRANSMEM        311..331
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          262..330
FT                   /note="HELP"
FT                   /evidence="ECO:0000259|Pfam:PF03451"
FT   REPEAT          623..657
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          752..793
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REGION          29..66
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          110..230
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        29..50
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        116..130
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        165..198
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        199..221
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   927 AA;  102761 MW;  1C2B2D9BD906816C CRC64;
     MLNQVCCSDG CTSSRKLSSS SAVDGIRHPA TSQLSESVAT NANGHVVSTE HRTKPATLDR
     STQTEPTLLQ VQEAGQDRLT LSRRVQSLHL EDALFPSESL PEGTRAKLHR VPGMEEEDEE
     QEEDEEGGGE QEKELTWTSL VEEPIQPTTM RGLQREDFQD GSCSPEEPGS ASVSLRTSDQ
     NLSARSGPLS TIQEGQKTLV RRNSEKLGNP ERQRKRLDKK AASSANLLTR SPSLENRAKE
     LVASAGSPGS RRGTYSQGQS IKMFIRGRPI TMYVPSNIQN YEDLKMEPPS ERLDLDWVYG
     YRGRDCRANL YFLPTGEAVY FIACVIVLYH INNRTQRHYR KHTDCVRCLT LHPDKVRVAS
     GQTAGVDKDG KPLQPCVHIW DSTTLVTLQQ IGLGAFQRGV GSVAFSFADS GAFLCVIDDS
     NEHMLSVWDC TKGTKHAEIK STNEAVFAVE FNPSDSTNII TCGKSHVYFW TLNGGQFTKK
     QGIFGKYKKP KFIQCFVFSL TGDVLTGDSE GNILTWGKSA ADVKTLGKGA KETFQIMRQT
     RAHEGSVFTL WTLHGGGLLS GGGKDRKIIR WSADLAPERE CEIPEKYGAV RTIADVDEEE
     LLVGTTRNAI LRGTFSDGFV AIVQGHVDEM WGLATHPSQN IFLTCGHDRQ VCLWNTEEHK
     LDWCITLEEY GLCADFCPNG SVVSVGLSTG RWMVLDLLTR EVVSESTDGN EQLSVMRYSP
     DGSFLAVGSH DNFIYIYNVT ESGRRYIRFG KCNGHSSFIT HLDWSKDGKY IMSNSGDYEI
     LYWDIAAGCK LLRNRYESKD REWASYTCVL GFHVMGVWLE GSDGTDINAL CRSHDERMVA
     VADDFCKVHL FQYPCPKPKA PSHRYEGHGS HVTNVCFTHS DSHLLSMGGK DTCILQWKVF
     GAGDSRERLA SASVSSTSTS SPEPVTG
//