ID A0A3Q1G422_9TELE Unreviewed; 323 AA.
AC A0A3Q1G422;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Syntaxin-18 {ECO:0000256|ARBA:ARBA00019409};
OS Acanthochromis polyacanthus (spiny chromis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Acanthochromis.
OX NCBI_TaxID=80966 {ECO:0000313|Ensembl:ENSAPOP00000022527.1, ECO:0000313|Proteomes:UP000257200};
RN [1] {ECO:0000313|Ensembl:ENSAPOP00000022527.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Syntaxin that may be involved in targeting and fusion of
CC Golgi-derived retrograde transport vesicles with the ER.
CC {ECO:0000256|ARBA:ARBA00003746}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004163}; Single-pass type IV membrane protein
CC {ECO:0000256|ARBA:ARBA00004163}. Membrane
CC {ECO:0000256|ARBA:ARBA00004211}; Single-pass type IV membrane protein
CC {ECO:0000256|ARBA:ARBA00004211}.
CC -!- SIMILARITY: Belongs to the syntaxin family.
CC {ECO:0000256|ARBA:ARBA00009063}.
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DR AlphaFoldDB; A0A3Q1G422; -.
DR STRING; 80966.ENSAPOP00000022527; -.
DR Ensembl; ENSAPOT00000013557.1; ENSAPOP00000022527.1; ENSAPOG00000003763.1.
DR GeneTree; ENSGT00390000014853; -.
DR InParanoid; A0A3Q1G422; -.
DR OrthoDB; 3032483at2759; -.
DR Proteomes; UP000257200; Unplaced.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005484; F:SNAP receptor activity; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
DR CDD; cd15850; SNARE_syntaxin18; 1.
DR Gene3D; 1.20.5.110; -; 1.
DR InterPro; IPR019529; Syntaxin-18_N.
DR InterPro; IPR006012; Syntaxin/epimorphin_CS.
DR PANTHER; PTHR15959; SYNTAXIN-18; 1.
DR PANTHER; PTHR15959:SF0; SYNTAXIN-18; 1.
DR Pfam; PF10496; Syntaxin-18_N; 1.
DR SUPFAM; SSF58038; SNARE fusion complex; 1.
DR PROSITE; PS00914; SYNTAXIN; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW ER-Golgi transport {ECO:0000256|ARBA:ARBA00022892};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000257200};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 300..321
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 4..91
FT /note="SNARE-complex protein Syntaxin-18 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF10496"
SQ SEQUENCE 323 AA; 37262 MW; FAA69D7068AFC7FF CRC64;
MAVDITLLFK ASVKTVKTRN KAIGIGFDST KDEIFKRSRP KGGFSPKAKE VITNITKLKE
FLLQHRKDYV SAGSLISSDL TRMTDSERDQ IDQDAQIFMR TCSEAIKQLR NEAEKQVTSA
QIKEHRGAVL DLVEMYLKGV CKIYSEQRAI RVKRMVDKKR LSRLAPEQHR RVEKTVEVEP
TQEKIVKEES SEKSVSEVLD DPVNPWEESR VEDELSPEEI QMFEQENQRL ISEMNSLVDE
VRTIEGKVVE ISRLQEIFAE KVLQQETEID SIHQLVVGAT ENVKEGNEDI REAIKNNAGF
RVWILFFLVM CSFSLLFLDW YDS
//
