ID A0A3Q1G878_9TELE Unreviewed; 376 AA.
AC A0A3Q1G878;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=EGF-like domain-containing protein {ECO:0000259|PROSITE:PS01186};
OS Acanthochromis polyacanthus (spiny chromis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Acanthochromis.
OX NCBI_TaxID=80966 {ECO:0000313|Ensembl:ENSAPOP00000026213.1, ECO:0000313|Proteomes:UP000257200};
RN [1] {ECO:0000313|Ensembl:ENSAPOP00000026213.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00124}.
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DR AlphaFoldDB; A0A3Q1G878; -.
DR STRING; 80966.ENSAPOP00000026213; -.
DR Ensembl; ENSAPOT00000004284.1; ENSAPOP00000026213.1; ENSAPOG00000009879.1.
DR GeneTree; ENSGT00940000164512; -.
DR InParanoid; A0A3Q1G878; -.
DR Proteomes; UP000257200; Unplaced.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR CDD; cd00112; LDLa; 6.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR Gene3D; 4.10.400.10; Low-density Lipoprotein Receptor; 6.
DR InterPro; IPR026823; cEGF.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR036055; LDL_receptor-like_sf.
DR InterPro; IPR023415; LDLR_class-A_CS.
DR InterPro; IPR002172; LDrepeatLR_classA_rpt.
DR PANTHER; PTHR24270:SF61; CD320 ANTIGEN; 1.
DR PANTHER; PTHR24270; LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED; 1.
DR Pfam; PF12662; cEGF; 1.
DR Pfam; PF00057; Ldl_recept_a; 6.
DR PRINTS; PR00261; LDLRECEPTOR.
DR SMART; SM00181; EGF; 3.
DR SMART; SM00179; EGF_CA; 2.
DR SMART; SM00192; LDLa; 6.
DR SUPFAM; SSF57196; EGF/Laminin; 2.
DR SUPFAM; SSF57424; LDL receptor-like module; 6.
DR PROSITE; PS01186; EGF_2; 2.
DR PROSITE; PS01187; EGF_CA; 1.
DR PROSITE; PS01209; LDLRA_1; 4.
DR PROSITE; PS50068; LDLRA_2; 6.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00124}; EGF-like domain {ECO:0000256|ARBA:ARBA00022536};
KW Membrane {ECO:0000256|ARBA:ARBA00022989};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000257200};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 182..197
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS01186"
FT DOMAIN 223..238
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS01186"
FT DISULFID 33..48
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 53..65
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 60..78
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 96..108
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 103..121
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 115..130
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 275..287
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 282..300
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 315..327
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 322..340
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
SQ SEQUENCE 376 AA; 41066 MW; E4C1784E928B431A CRC64;
HLLTHGRTCS SDQFTCPTWY PGHPKCVPFS LVCDRVNDCG DGSDELHCTY DTCSSSQFTC
GNGACISNYY ICDGVNDCMD GSDEADSLCV TPQPTCAPGQ YLCKSGECIE DSKVCNSLKD
CQDNSDEKGC ETILTSCKSH AKSCLFRLPL LSSFCAGVNE CLSPPIHQCA QICTDTLTGY
YCSCHPGYKL MPDGKACEDI DECLSTPAVC SQICENAFGS YHCKCAPGYI REPDGRTCRQ
NSGIAPCVPI WWKCDGQSDC GDGSDEPQTC PPRLCPIGQF QCQDGNCIFP GFICDNEPHC
PDKSDEDATC SQKTCSPGQF QCANGRCLPF SYVCDAQDDC GDGSDEPYEI CSKSDIRKRQ
FNRNKAIEKQ EHYTVQ
//
