ID A0A3Q1GA94_9TELE Unreviewed; 896 AA.
AC A0A3Q1GA94;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Metabotropic glutamate receptor 7-like {ECO:0000313|Ensembl:ENSAPOP00000026983.1};
GN Name=GRM7 {ECO:0000313|Ensembl:ENSAPOP00000026983.1};
OS Acanthochromis polyacanthus (spiny chromis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Acanthochromis.
OX NCBI_TaxID=80966 {ECO:0000313|Ensembl:ENSAPOP00000026983.1, ECO:0000313|Proteomes:UP000257200};
RN [1] {ECO:0000313|Ensembl:ENSAPOP00000026983.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 3 family.
CC {ECO:0000256|ARBA:ARBA00007242}.
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DR AlphaFoldDB; A0A3Q1GA94; -.
DR STRING; 80966.ENSAPOP00000026983; -.
DR Ensembl; ENSAPOT00000002351.1; ENSAPOP00000026983.1; ENSAPOG00000011198.1.
DR GeneTree; ENSGT01030000234648; -.
DR InParanoid; A0A3Q1GA94; -.
DR Proteomes; UP000257200; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR CDD; cd15451; 7tmC_mGluR7; 1.
DR CDD; cd06376; PBP1_mGluR_groupIII; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 2.10.50.30; GPCR, family 3, nine cysteines domain; 1.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR000337; GPCR_3.
DR InterPro; IPR011500; GPCR_3_9-Cys_dom.
DR InterPro; IPR038550; GPCR_3_9-Cys_sf.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR017979; GPCR_3_CS.
DR InterPro; IPR001786; GPCR_3_mGluR4.
DR InterPro; IPR000162; GPCR_3_mtglu_rcpt.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR24060; METABOTROPIC GLUTAMATE RECEPTOR; 1.
DR PANTHER; PTHR24060:SF98; METABOTROPIC GLUTAMATE RECEPTOR 7; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF07562; NCD3G; 1.
DR PRINTS; PR00248; GPCRMGR.
DR PRINTS; PR01054; MTABOTROPC4R.
DR PRINTS; PR00593; MTABOTROPICR.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00979; G_PROTEIN_RECEP_F3_1; 1.
DR PROSITE; PS00980; G_PROTEIN_RECEP_F3_2; 1.
DR PROSITE; PS00981; G_PROTEIN_RECEP_F3_3; 1.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000257200};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..30
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 31..896
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018657749"
FT TRANSMEM 583..609
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 621..641
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 653..674
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 747..768
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 780..802
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 822..844
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 583..857
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
FT REGION 864..896
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 896 AA; 100346 MW; 6204D82B1C95D494 CRC64;
MMARPGECVK LSSIWRLLWL MRTVVDVALP QETYAPHSIR TEGHLTLGGL FPVHTRSIDG
TPCRDLKKEN GIQRLEAMMY ALDQINQDDQ LLPNITLGAR VLDTCSRDTY ALEQSLTFVQ
ALITKDTSDV RCTNGEPPVF VKPEKVVGVI GASASSVSIM VANILRLFQI PQISYASTAP
ELSDDRRYDF FSRVVPPDSF QAQAMVDIIR ALGWTYVSTI ASEGSYGEKG VEAFTQLSKE
AGGICIAQSL KIPHNPKLED YDKTVQQLME TSNSRAVIIF ASEEDIRGVL NATKRANQVG
HFLWIGSDSW GAKSSPIHQL EDVAVGAVTI LPKRSSIKGF DEYFTALTLE NNRRNVWFAE
FWEENFDCRL LSASKREDTS RKCTGQERIG IDSKYEQEGK VQFVIDAVYA MAHALHNMQR
DLCPDHPGVC PQMEAAEGKV LLRYIRNTSF NGSAGTPVVF NKNGDAPGRY DLFQFQMTNS
STPEYKVVGQ WVESLQLKLE ELQWPDGEQE VPISVCSLPC KTGQRKKKVK GMPCCWHCEL
CDGYQYQYDE TSCRLCSYNM RPNSNRTACQ PIPIVKLEWH SPWAIIPVFL AMLGIIATIF
VMATFVRYND TPIVRASGRE LSYVLLTGIF LCYIITFLMI AKPDIAVCAF RRIFLGLGMC
ISYAALLTKT NRIYRIFEQG KQTVTAPRFI SPTSQIAITS SLICVQLLGV LVWFAVDPPN
TIIDYDEQKT INPKLARGVL KCDITDLQII CSLGYSILLM VTCTIYAIKT RDVPEDFNEA
KPIGFTMYTT CIVWLAFIPI FFGTAQSAEK LYIQTTTLTI SMNLSASVAL GMLYMPKVYI
IIFHPELNVQ KRKRSFKAVV TAATMSSRLS QKPNERPNGE AKTELCENPA ADPMSK
//
