ID   A0A3Q1GAL7_9TELE        Unreviewed;       520 AA.
AC   A0A3Q1GAL7;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Potassium calcium-activated channel subfamily N member 4 {ECO:0000313|Ensembl:ENSAPOP00000027581.1};
OS   Acanthochromis polyacanthus (spiny chromis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Acanthochromis.
OX   NCBI_TaxID=80966 {ECO:0000313|Ensembl:ENSAPOP00000027581.1, ECO:0000313|Proteomes:UP000257200};
RN   [1] {ECO:0000313|Ensembl:ENSAPOP00000027581.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   AlphaFoldDB; A0A3Q1GAL7; -.
DR   STRING; 80966.ENSAPOP00000027581; -.
DR   Ensembl; ENSAPOT00000000828.1; ENSAPOP00000027581.1; ENSAPOG00000012212.1.
DR   GeneTree; ENSGT00950000182904; -.
DR   InParanoid; A0A3Q1GAL7; -.
DR   OrthoDB; 4200919at2759; -.
DR   Proteomes; UP000257200; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR   GO; GO:0016286; F:small conductance calcium-activated potassium channel activity; IEA:InterPro.
DR   Gene3D; 1.10.287.70; -; 2.
DR   InterPro; IPR004178; CaM-bd_dom.
DR   InterPro; IPR036122; CaM-bd_dom_sf.
DR   InterPro; IPR015449; K_chnl_Ca-activ_SK.
DR   InterPro; IPR013099; K_chnl_dom.
DR   PANTHER; PTHR10153:SF41; INTERMEDIATE CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL PROTEIN 4; 1.
DR   PANTHER; PTHR10153; SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL; 1.
DR   Pfam; PF02888; CaMBD; 1.
DR   Pfam; PF07885; Ion_trans_2; 1.
DR   Pfam; PF03530; SK_channel; 1.
DR   SMART; SM01053; CaMBD; 1.
DR   SUPFAM; SSF81327; Small-conductance potassium channel; 1.
DR   SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE   4: Predicted;
KW   Calmodulin-binding {ECO:0000256|ARBA:ARBA00022860};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000257200};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        105..131
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        137..159
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        186..205
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        225..246
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        292..311
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        323..340
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          394..468
FT                   /note="Calmodulin-binding"
FT                   /evidence="ECO:0000259|SMART:SM01053"
FT   REGION          1..25
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          473..500
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        10..25
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   520 AA;  58870 MW;  0E2C04BBF2E151F1 CRC64;
     MPSPAREESN GERGQAKDGA AERGDDAGGR LVCALEMEMT NRSPHGDSKV DYVNNCDGLV
     GRNCGDSAQV SVPLSLHGKR TTHMEGDDLY RLRDRKLLLE DRKRLCALAL GTALLGILLM
     IIHAEMCPFV YKPGSNAALV INSSISLSTG CLLILIIAFH YKDVRLFVID NHNQVDWRIA
     MTSHRVLVIT LELLVCTIHP VGSYWEEGPR SNSSSSAQLC VSSHHGEALL GMELLFSVLM
     FLRLYLVHRA ILLHSKMLLS ASYRSIGSLN NINFTFRFVL KVLMNQHPAR TLLVFILFFW
     LTASWMLTLC ERQTQASTGH METALWLIAI TFLTVGYGDV APNTSCGKAV CLFTGVMLKK
     GKQGVACTAM LVAIVTEKLA LNKGEKHVHY FMLDIQISKR IRHAAANVLR ECWLLHRTNL
     TKGNRGEHRR HQRCLLEAIR VFRNLRLKQR KLRDYVSEMV DLPKMQMIMC DLSANWNNSY
     RELEQRILSM EQKLDELSRC FQQSSELLSQ VLRHRNPEIR
//