ID   A0A3Q1GKD0_9TELE        Unreviewed;       488 AA.
AC   A0A3Q1GKD0;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Interferon regulatory factor 6 {ECO:0000313|Ensembl:ENSAPOP00000029974.1};
OS   Acanthochromis polyacanthus (spiny chromis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Acanthochromis.
OX   NCBI_TaxID=80966 {ECO:0000313|Ensembl:ENSAPOP00000029974.1, ECO:0000313|Proteomes:UP000257200};
RN   [1] {ECO:0000313|Ensembl:ENSAPOP00000029974.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3Q1GKD0; -.
DR   Ensembl; ENSAPOT00000021630.1; ENSAPOP00000029974.1; ENSAPOG00000016284.1.
DR   GeneTree; ENSGT00940000157451; -.
DR   OrthoDB; 3740806at2759; -.
DR   Proteomes; UP000257200; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000976; F:transcription cis-regulatory region binding; IEA:InterPro.
DR   GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:UniProt.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:UniProt.
DR   CDD; cd00103; IRF; 1.
DR   Gene3D; 2.60.200.10; -; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR019817; Interferon_reg_fac_CS.
DR   InterPro; IPR001346; Interferon_reg_fact_DNA-bd_dom.
DR   InterPro; IPR019471; Interferon_reg_factor-3.
DR   InterPro; IPR017855; SMAD-like_dom_sf.
DR   InterPro; IPR008984; SMAD_FHA_dom_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11949; INTERFERON REGULATORY FACTOR; 1.
DR   PANTHER; PTHR11949:SF9; INTERFERON REGULATORY FACTOR 6; 1.
DR   Pfam; PF00605; IRF; 1.
DR   Pfam; PF10401; IRF-3; 1.
DR   PRINTS; PR00267; INTFRNREGFCT.
DR   SMART; SM00348; IRF; 1.
DR   SMART; SM01243; IRF-3; 1.
DR   SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS00601; IRF_1; 1.
DR   PROSITE; PS51507; IRF_2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000257200}.
FT   DOMAIN          7..115
FT                   /note="IRF tryptophan pentad repeat"
FT                   /evidence="ECO:0000259|PROSITE:PS51507"
FT   REGION          119..163
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   488 AA;  54985 MW;  EDDE80A38DC56A33 CRC64;
     MSVTPRRVRL KPWLVAQVDS GRYPGLEWIN RDAMRFRIPW KHATRHTPQH EDEDTIFKAW
     AVETGKFQEG VDEPDPAKWK AQLRCALNKS REFNLVYDGT KEVPMNPLKI YDVCDIPQPL
     SNQGSSDAGS WTPHDDDGVE EDLPDTPGSP PPYPSNGASP SPLIMWSPET PMQPLSCPPS
     NEVWPKEEPV KIWPKEEPVD VEMQPTPLGD LPPAPLPDPS MQTPLLTDAL FASPEMWISS
     LPMTDLEVLF LYRGREMCPI VNVSNPQGCR LFYGDLGPMV NQEELFGPIN LEQLRFPSTE
     HITNDKQRIF TSRLLDVMDR GLILEVSGHD IYAVRLCQCK VYWSGPCANP GAPNLIERQR
     KVKLFCLESF LSGVIAHQRG QTPNPPEFEI NLCFGEEWPD GKPRERKLIM VQVIPVVARM
     ISEMFSGDNT RSFDSGSVRL QISIPDIKDN IVTHLKQLYC LLQGHQGQDG WALPNGSGLN
     IAQALQNQ
//