ID A0A3Q1GLD9_9TELE Unreviewed; 649 AA.
AC A0A3Q1GLD9;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Lutropin-choriogonadotropic hormone receptor-like {ECO:0000313|Ensembl:ENSAPOP00000031283.1};
OS Acanthochromis polyacanthus (spiny chromis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Acanthochromis.
OX NCBI_TaxID=80966 {ECO:0000313|Ensembl:ENSAPOP00000031283.1, ECO:0000313|Proteomes:UP000257200};
RN [1] {ECO:0000313|Ensembl:ENSAPOP00000031283.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR AlphaFoldDB; A0A3Q1GLD9; -.
DR Ensembl; ENSAPOT00000024113.1; ENSAPOP00000031283.1; ENSAPOG00000018739.1.
DR GeneTree; ENSGT00940000158952; -.
DR Proteomes; UP000257200; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0016500; F:protein-hormone receptor activity; IEA:InterPro.
DR CDD; cd15136; 7tmA_Glyco_hormone_R; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR002131; Gphrmn_rcpt_fam.
DR InterPro; IPR026906; LRR_5.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR24372:SF5; FOLLICLE-STIMULATING HORMONE RECEPTOR; 1.
DR PANTHER; PTHR24372; GLYCOPROTEIN HORMONE RECEPTOR; 1.
DR Pfam; PF00001; 7tm_1; 1.
DR Pfam; PF13306; LRR_5; 2.
DR PRINTS; PR00373; GLYCHORMONER.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000257200};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..649
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018792399"
FT TRANSMEM 321..346
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 358..382
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 402..423
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 444..467
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 487..512
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 533..555
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 567..587
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 337..584
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
SQ SEQUENCE 649 AA; 72401 MW; C733BFAECE68251E CRC64;
MVVMRLIMLV AVVIKVAAAF APGYEVDNKS GPNAGLTKQT QDPCYKVPFG ATEIPSNIPR
SIQCLTILKN DVLQKITAFA FASLPRSISG NVALERIEAF AFSDLPELNE IIITKSKHLS
FIHPDAFRNI TKLQFLTISS TGLRIFPDFS KIHSTANRFL LDLEENSHIE KVPANAFRGL
CTQTFMEIRL TRNGIKEVAS DAFNGTKMKK LDISQTALSS LPDSILGGLT RLFAESAFHL
KELPPLHLFT KLRFANLTYS SHCCAFQNMH RNRSCWHSWC EDPNAKNYPR FYRDCCSNST
SITCTPVPDD FNPCEDIMSG VLLRVLIWII SILALLGNAV VLFVLLGTRS KLTVPRFLMC
HLAFADLCMG IYLVVIATVD MLTRGRYYNH AIDWQMGLGC NAAGFFTVFA SELSVFTLMA
ITVERWHTIT HALRLDQKLR LRHACIIMAA GWIFSSLAAL LPTVGVSSYG KVSICLPMDV
ETLVSQVYVV SLLLLNILAF FCVCGCYLSI YLTFRKPSSA PAHADTRVAQ RMAVLIFTDF
ICMAPISFFA VSAALKLPLI TVSDSKLLLV LFYPINSCSN PFLYAFFTRT FRQDFFLLAA
RFGLFKTRAQ IYRTESSSCQ QPAWTSPKSS RIMTCSLANT LSLDGKQES
//
