ID A0A3Q1GM79_9TELE Unreviewed; 1069 AA.
AC A0A3Q1GM79;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=MDS1 and EVI1 complex locus {ECO:0000313|Ensembl:ENSAPOP00000018455.1};
GN Name=MECOM {ECO:0000313|Ensembl:ENSAPOP00000018455.1};
OS Acanthochromis polyacanthus (spiny chromis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Acanthochromis.
OX NCBI_TaxID=80966 {ECO:0000313|Ensembl:ENSAPOP00000018455.1, ECO:0000313|Proteomes:UP000257200};
RN [1] {ECO:0000313|Ensembl:ENSAPOP00000018455.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR AlphaFoldDB; A0A3Q1GM79; -.
DR Ensembl; ENSAPOT00000028032.1; ENSAPOP00000018455.1; ENSAPOG00000021846.1.
DR GeneTree; ENSGT00940000157208; -.
DR Proteomes; UP000257200; Unplaced.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 8.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24393:SF34; FEZ FAMILY ZINC FINGER PROTEIN ERM; 1.
DR PANTHER; PTHR24393; ZINC FINGER PROTEIN; 1.
DR Pfam; PF00096; zf-C2H2; 8.
DR Pfam; PF13912; zf-C2H2_6; 1.
DR SMART; SM00355; ZnF_C2H2; 10.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 5.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 7.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 10.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Reference proteome {ECO:0000313|Proteomes:UP000257200};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 26..53
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 83..110
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 111..138
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 139..168
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 169..196
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 197..224
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 226..253
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 747..774
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 775..803
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 804..831
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 326..482
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 540..635
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 826..847
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 866..1018
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 382..428
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 430..451
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 578..592
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 616..635
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 830..845
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 904..921
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 959..993
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1069 AA; 118353 MW; 34C5B4E3935E9D0F CRC64;
MSTCTPHLNA QHDNFPPFHH AEERQYRCED CDQHFESRNQ LLDHQKQPCG MPPTSFLTPG
VDNDLKAQEP QDLRPLHMSH GLHECKECDQ VFPDVQSLEA HTLSHSEERE YKCDQCPKAF
NWKSNLIRHQ MSHDSGKHYE CENCSKQVFT DPSNLQRHIR SQHVGARAHA CSDCGKTFAT
SSGLKQHKHI HSSVKPFMCE VCHKSYTQFS NLCRHKRMHA DCRTQIKCKD CGQMFSTTSS
LNKHRRFCEG KNHFTAGGLF AQGMPLPGAP GLDKSALAMG HSSAGLADYF GASRHHSGLT
FPAAPAFPFS FPGLFPSGLY HRPPLIPATT SPVRQPAHAP VAGPGAELSK SPLLPPSPGA
QESRELLKAL RKDGGSPGNQ IPGSELHIQG SSSSTKQQNK QSDQSESSDL DDVSTPSGSD
LESTSGSELE SDMDSERERG AARENGKGPK RKATEGGSQS PSLMGSGAAK DFPGPSLIPS
SLDEHTAVTG AVNDSIKAIA SIAEKYFGST GLAGLQDKKV GSLPYPSMFP LPFFPAFSPP
VYPFPDRDLR PAGLKGEPQS PADDGKKAQG KSSSESPFDL TTKRKEEKLA PFAPSKPEVS
HATGQDQPLD LSLGSRGRRR SAREEDTKKN LNYEDKKGVM EIPKADTSLQ HARPTPFFMD
PIYSRVEKRR MSDPFETLKD KYMRPAPGFL FHPQMTAIEN MAEKLETFNS LKPESGDLLR
SVPSMFDFRA PPSALPETLL RKGKERYTCR YCGKIFPRSA NLTRHLRTHT GEQPYRCKYC
DRSFSISSNL QRHIRNIHNK EKPFKCHLCD RCFGQQTNLD RHLKKHENGN LSGTAMSSPQ
SELDSGSAIL DDKEDSYFNE IRNFISNTSQ NQASPDPSEE GLNGGPFEEE KPLMASHGSR
DLEDEEAEEL EADEEEGEDN SNTPEKPEGK VLPGNLSDDI MQDEMDFSEQ NDLNLSCKTS
PRRYKDEEDQ SSYSALDHIH RFSEMRKLEE SELSDGDGDE DDGSFGSPSL TEAVKQPLFR
KSKSQAYAMM LSLAEKDSLH PATHTPATMW HSLARAAAES SAIQSLSHV
//
