ID   A0A3Q1GPG2_9TELE        Unreviewed;      1049 AA.
AC   A0A3Q1GPG2;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Zinc fingers and homeoboxes protein 2-like {ECO:0000313|Ensembl:ENSAPOP00000032323.1};
OS   Acanthochromis polyacanthus (spiny chromis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Acanthochromis.
OX   NCBI_TaxID=80966 {ECO:0000313|Ensembl:ENSAPOP00000032323.1, ECO:0000313|Proteomes:UP000257200};
RN   [1] {ECO:0000313|Ensembl:ENSAPOP00000032323.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
CC   -!- SIMILARITY: Belongs to the ZHX family. {ECO:0000256|ARBA:ARBA00007440}.
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DR   STRING; 80966.ENSAPOP00000016985; -.
DR   Ensembl; ENSAPOT00000026117.1; ENSAPOP00000032323.1; ENSAPOG00000020128.1.
DR   Ensembl; ENSAPOT00000026120.1; ENSAPOP00000016985.1; ENSAPOG00000020128.1.
DR   GeneTree; ENSGT00950000182893; -.
DR   OrthoDB; 5350395at2759; -.
DR   Proteomes; UP000257200; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   CDD; cd00086; homeodomain; 2.
DR   Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR   Gene3D; 1.10.10.60; Homeodomain-like; 3.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR001356; Homeobox_dom.
DR   InterPro; IPR041057; ZHX_Znf_C2H2.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   PANTHER; PTHR15467:SF5; ZINC FINGERS AND HOMEOBOXES PROTEIN 2; 1.
DR   PANTHER; PTHR15467; ZINC-FINGERS AND HOMEOBOXES RELATED; 1.
DR   Pfam; PF00046; Homeodomain; 1.
DR   Pfam; PF18387; zf_C2H2_ZHX; 1.
DR   SMART; SM00389; HOX; 3.
DR   SMART; SM00355; ZnF_C2H2; 2.
DR   SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 2.
DR   SUPFAM; SSF46689; Homeodomain-like; 3.
DR   PROSITE; PS50071; HOMEOBOX_2; 3.
PE   3: Inferred from homology;
KW   Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW   ProRule:PRU00108};
KW   Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW   ProRule:PRU00108};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW   ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000257200}.
FT   DOMAIN          320..363
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000259|PROSITE:PS50071"
FT   DOMAIN          735..785
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000259|PROSITE:PS50071"
FT   DOMAIN          868..915
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000259|PROSITE:PS50071"
FT   DNA_BIND        322..364
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT   DNA_BIND        737..786
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT   DNA_BIND        870..916
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT   REGION          1..126
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          520..540
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          592..612
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          829..864
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        52..78
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        79..122
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        523..540
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        849..864
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1049 AA;  115126 MW;  6C0883D0846B4EB2 CRC64;
     MSSRRKSSNP CMVRVISDLP KEQDDPEEVM DMEIFVSNNI AEKEQSEPSE PAEKSQDPQQ
     ENLVNSGQQV FPKKVENQNP EPSEQKEQSG KEDQPSVIED EETTGEKDKD EAESDPASQK
     KQPKGYECKY CPFSTQNLND FKEHVDSSHP NVILNPLYLC AVCNFNTKKF DSLTEHNESQ
     HPGETNFKFK RIKTNNQTIL EQTIEGKDNE CEVTNEQGES NSSSVFSPCI STTVKTPGNI
     QALFGGSELK SHLDSLTQKD QITAVNINGT VIIPEPTILQ GLSHVTPMLQ RPPNFNSVPK
     IAVPLNTTKY NPSLDNNLTL ITSFNKFPYP THAELSWLTA ASKHPEEQIK VWFTTQRLKQ
     GITWSPEEVE EARKKMFNGS IPPAHHTFNI LPTSPISQPS AKASQQPVVH TTVEHPGHVR
     TTVSNGLNIP NNTSPGSGHT LKRSLPTHLT TVLGPELKRP IMAVAPHSGD PKDKVLMAPP
     PPPPPYKDRL PMAPPPVPME IKRPVALPLV TTEMKRPSTA VPLMQPPLSS LSPSSSSKGK
     ILSALGNPKT KPVVSLPCIV FPESLTRPMI APPPIFAPSF KNSLLLPRAV TATSKEKHPN
     SHTLPAADPN LPNSPPLITS QVRRPPIIQS ICAPAKAPAQ IPGFPLDGKK LKEQQGVELK
     ANYHRGDKVV SPLTEANGIS RIDGKWSHDQ TSPSHNNGIV HLDSGETPTA LKPDFQQKSS
     VLTQFPLLER MKGKTAKQLK VLEENFLRNS FPSHSDVDNL STTTRLSHQE IDSWFVERRA
     LRDNLEQALL NSMGTKRMGV SGITAIAEKQ LQQQQTLQLN GVHKPSTGVG HLKSPPPPSH
     ALSISGPGTI APSVPNPNSC SVPPDSRSLA LLKDDFAQTR WPSPEEFSQL EGRMGLARAD
     LARWFTDGRL QTGNLELTEL FHNSGVNGGQ GMAVCSLENT PSGIIQRCQE GALTNNNSSS
     KVLEVELGWL MDQRTNSQQH DELQDRFAGR LRQQSVAELK NGGQNGGVLG GAREVFGSWL
     EDGHSRRGRE LLLDRERKMA EDASGRLTG
//