ID   A0A3Q1GPM1_9TELE        Unreviewed;       686 AA.
AC   A0A3Q1GPM1;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Amyloid beta A4 precursor protein-binding family B member 2-like {ECO:0000313|Ensembl:ENSAPOP00000019230.1};
GN   Name=APBB2 {ECO:0000313|Ensembl:ENSAPOP00000019230.1};
OS   Acanthochromis polyacanthus (spiny chromis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Acanthochromis.
OX   NCBI_TaxID=80966 {ECO:0000313|Ensembl:ENSAPOP00000019230.1, ECO:0000313|Proteomes:UP000257200};
RN   [1] {ECO:0000313|Ensembl:ENSAPOP00000019230.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3Q1GPM1; -.
DR   Ensembl; ENSAPOT00000029057.1; ENSAPOP00000019230.1; ENSAPOG00000022762.1.
DR   GeneTree; ENSGT00390000000002; -.
DR   Proteomes; UP000257200; Unplaced.
DR   GO; GO:0001540; F:amyloid-beta binding; IEA:InterPro.
DR   CDD; cd01272; PTB1_Fe65; 1.
DR   CDD; cd01271; PTB2_Fe65; 1.
DR   CDD; cd00201; WW; 1.
DR   Gene3D; 2.20.70.10; -; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR   InterPro; IPR039576; APBB1/2/3.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR006020; PTB/PI_dom.
DR   InterPro; IPR001202; WW_dom.
DR   InterPro; IPR036020; WW_dom_sf.
DR   PANTHER; PTHR14058; AMYLOID BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B; 1.
DR   PANTHER; PTHR14058:SF11; AMYLOID BETA PRECURSOR PROTEIN BINDING FAMILY B MEMBER 2; 1.
DR   Pfam; PF00640; PID; 2.
DR   Pfam; PF00397; WW; 1.
DR   SMART; SM00462; PTB; 2.
DR   SMART; SM00456; WW; 1.
DR   SUPFAM; SSF50729; PH domain-like; 2.
DR   SUPFAM; SSF51045; WW domain; 1.
DR   PROSITE; PS01179; PID; 2.
DR   PROSITE; PS01159; WW_DOMAIN_1; 1.
DR   PROSITE; PS50020; WW_DOMAIN_2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000257200}.
FT   DOMAIN          253..285
FT                   /note="WW"
FT                   /evidence="ECO:0000259|PROSITE:PS50020"
FT   DOMAIN          363..490
FT                   /note="PID"
FT                   /evidence="ECO:0000259|PROSITE:PS01179"
FT   DOMAIN          516..642
FT                   /note="PID"
FT                   /evidence="ECO:0000259|PROSITE:PS01179"
FT   REGION          74..130
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          158..259
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          279..326
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          643..663
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        78..130
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        163..177
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        181..196
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        211..252
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        295..313
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        648..663
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   686 AA;  74658 MW;  23779827AD05CAE9 CRC64;
     MSEIIKSDLS CATMMSVDVT NRNGPAATPP TSLSLRSSHN QLLSSDVINQ GSATPPKCRK
     KYALTSIQAA MGLGEAVPPS SSSPSSSPSQ SSTPNNPKLA KNGVNQLRKA GQDHNKNTTG
     PDPMDLECNS ETLSPVKNHK VSPSLELITD LHSNLKLLKS GKNSPVPPPP SPPRQASPED
     TPLLSVASCP SSSSSSPETK KDRRTGAKTD CALNRIQNLN PSDEELSWTT LSQESNSPEE
     TDIWSEQSFQ TDPDLPPGWK KITDMAGIYY WHIPTGTTQW ERPSPALGDH TASTPRKHSL
     GSLSPSPTPD HEDLQAATVN PDPSLKEFEG ATLRYASLKL RNRPAVEEEE SSGVNSDPEA
     KCFAVRSLGW VEMAEEDLAP GKSSVAVNNC IRQLSYCKND IRDTVGIWGE GKDMYLVLEN
     NMLNLVDPMD RSVLHSQPIA SIRVWGVGRD NGRDFAYVAR DKNTRILKCH VFRCDTPAKA
     IATSLHEICS RVSCSHSLHN NCDTEFPTPK TELVQKFQVL YLGMLPVARP IGMDILNGAI
     DSLIGSSSRE DWTPVALNVA DATVTISKDK DEEEVLVECR VRFLSFMGVG RDVHTFAFIM
     DAGGHRFDCH VFWCDPNAGN VSEAVQAACM LRYQKCLVAR PPSQKACGSS PPGDSVSRRV
     STSVKRGVLS LIDTLKQKRP VTELPQ
//