ID A0A3Q1GPM6_9TELE Unreviewed; 426 AA.
AC A0A3Q1GPM6;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=SH3 and cysteine-rich domain-containing protein 2-like {ECO:0000313|Ensembl:ENSAPOP00000032378.1};
GN Name=STAC2 {ECO:0000313|Ensembl:ENSAPOP00000032378.1};
OS Acanthochromis polyacanthus (spiny chromis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Acanthochromis.
OX NCBI_TaxID=80966 {ECO:0000313|Ensembl:ENSAPOP00000032378.1, ECO:0000313|Proteomes:UP000257200};
RN [1] {ECO:0000313|Ensembl:ENSAPOP00000032378.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane, sarcolemma
CC {ECO:0000256|ARBA:ARBA00004278}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004278}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004278}.
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DR AlphaFoldDB; A0A3Q1GPM6; -.
DR STRING; 80966.ENSAPOP00000032378; -.
DR Ensembl; ENSAPOT00000026221.1; ENSAPOP00000032378.1; ENSAPOG00000020194.1.
DR GeneTree; ENSGT00950000183092; -.
DR InParanoid; A0A3Q1GPM6; -.
DR Proteomes; UP000257200; Unplaced.
DR GO; GO:0042383; C:sarcolemma; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0048468; P:cell development; IEA:UniProt.
DR Gene3D; 3.30.60.20; -; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR046349; C1-like_sf.
DR InterPro; IPR002219; PE/DAG-bd.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR039688; STAC1/2/3.
DR PANTHER; PTHR15135:SF5; SH3 AND CYSTEINE-RICH DOMAIN-CONTAINING PROTEIN 2; 1.
DR PANTHER; PTHR15135; STAC; 1.
DR Pfam; PF00130; C1_1; 1.
DR Pfam; PF00018; SH3_1; 1.
DR Pfam; PF16664; STAC2_u1; 1.
DR PRINTS; PR00499; P67PHOX.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00109; C1; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF57889; Cysteine-rich domain; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50002; SH3; 1.
DR PROSITE; PS00479; ZF_DAG_PE_1; 1.
DR PROSITE; PS50081; ZF_DAG_PE_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000257200};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}; Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 123..174
FT /note="Phorbol-ester/DAG-type"
FT /evidence="ECO:0000259|PROSITE:PS50081"
FT DOMAIN 308..367
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 61..115
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 230..300
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 405..426
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 64..81
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 86..115
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 243..258
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 426 AA; 47590 MW; 7F086EC80BDFED28 CRC64;
MMTENNEMET ESQLQRSPST MSIQPVSSKL QRLKRSLSFK TMMRSKSVEN FFQRSYSDAR
LPPDFITDPP PPSPPLLPGS PVVGERSPSI SPSLSPNPSI ASHSPSLSLS PSLPSKPARP
QVNHCFQDHV FRKPTNCQHC KHMIVGNSKQ ALRCKTCKMA AHLWCTSELS QQLCHGKSGA
FKRNFSSPML VNEQLAVVKE VQPIQEAVQR RVDPVYAALR YGTSLAQMSR SSFGSLSESP
TRSLEEAGEE RPPRQSSMDE EISQEPGDLP AAETEMEKEE KEEEEAAEQS LPPADENSVK
VPKRIEVHSI HTYVALYRFL PQEQNDLELH PGDRVQVTDD SNEEWWKGKS GDRVGFFPAN
FVQRVRPGER VWRVVQGVSG SRGRGHMAVR ESQWLISADI RWSEAQTAGN KAQPGKQQHS
RGGFGP
//
