ID   A0A3Q1GPN8_9TELE        Unreviewed;       518 AA.
AC   A0A3Q1GPN8;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Fibroblast growth factor receptor substrate 2-like {ECO:0000313|Ensembl:ENSAPOP00000031504.1};
GN   Name=FRS3 {ECO:0000313|Ensembl:ENSAPOP00000031504.1};
OS   Acanthochromis polyacanthus (spiny chromis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Acanthochromis.
OX   NCBI_TaxID=80966 {ECO:0000313|Ensembl:ENSAPOP00000031504.1, ECO:0000313|Proteomes:UP000257200};
RN   [1] {ECO:0000313|Ensembl:ENSAPOP00000031504.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3Q1GPN8; -.
DR   Ensembl; ENSAPOT00000024511.1; ENSAPOP00000031504.1; ENSAPOG00000018803.1.
DR   GeneTree; ENSGT00940000159495; -.
DR   Proteomes; UP000257200; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd01202; PTB_FRS2; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR038742; FRS2_PTB.
DR   InterPro; IPR002404; IRS_PTB.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   PANTHER; PTHR21258; DOCKING PROTEIN RELATED; 1.
DR   PANTHER; PTHR21258:SF39; FIBROBLAST GROWTH FACTOR RECEPTOR SUBSTRATE 3; 1.
DR   Pfam; PF02174; IRS; 1.
DR   SMART; SM01244; IRS; 1.
DR   SMART; SM00310; PTBI; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   PROSITE; PS51064; IRS_PTB; 1.
PE   4: Predicted;
KW   Lipoprotein {ECO:0000256|ARBA:ARBA00022707};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Myristate {ECO:0000256|ARBA:ARBA00022707};
KW   Reference proteome {ECO:0000313|Proteomes:UP000257200}.
FT   DOMAIN          13..115
FT                   /note="IRS-type PTB"
FT                   /evidence="ECO:0000259|PROSITE:PS51064"
FT   REGION          205..225
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          270..299
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          385..405
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          444..475
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          493..518
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   518 AA;  58134 MW;  8B6CD1EB4A62E452 CRC64;
     MGSCWSCLYR DPIRDNHLTK FKVTNVDDEG NELGSGIMEL TQTELILHTR KRDAIRWPYL
     CLRRYGYDSN LFSFESGRRC QTGQGIFAFK CSRAEEIFNL LQELMQCNSI NVVEESMMMS
     RSGHTPEMDM SRTPQTPNTP AFPVQAFPNG YPGYPIRGDS SQPSLADDHG HSLMGLEDQT
     HTYVNTVSME GDLSMRHCVH SLPEVRPSTF PETTRGAMPV GGQGNPQSNL RCCPLDEHKD
     PQVFLQPSSQ EVKFMLGPTP AQRHLLERER ERHGHNPHSL QPVEGAAGSE TEGDEPSIGE
     LTYENINGLR GVRKQRLSPS SVSQSVGSSR HRRTALLNYE NLPSLPPVWE YRFSEGPGTP
     NGYHQDSRGI HRDALQNYVN TEQVQPPRLR HACPPHPRPC QPDRGGRIFS FDFRRRSRSG
     VGGCEHSHMP PSRQLNYIQV DLEGEPPCQG LSSGGAQTQP QHQRLPPKKC GPQAPRRSEC
     YAVIDLKKTA AMSNLQKALP RDDGTSRKTR HNSTDLPL
//