ID   A0A3Q1GUK0_9TELE        Unreviewed;       687 AA.
AC   A0A3Q1GUK0;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=Vacuolar protein sorting-associated protein 16 homolog {ECO:0000256|ARBA:ARBA00017947};
OS   Acanthochromis polyacanthus (spiny chromis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Acanthochromis.
OX   NCBI_TaxID=80966 {ECO:0000313|Ensembl:ENSAPOP00000034128.1, ECO:0000313|Proteomes:UP000257200};
RN   [1] {ECO:0000313|Ensembl:ENSAPOP00000034128.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Early endosome {ECO:0000256|ARBA:ARBA00004412}.
CC   -!- SIMILARITY: Belongs to the VPS16 family.
CC       {ECO:0000256|ARBA:ARBA00009250}.
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DR   AlphaFoldDB; A0A3Q1GUK0; -.
DR   STRING; 80966.ENSAPOP00000034128; -.
DR   Ensembl; ENSAPOT00000034936.1; ENSAPOP00000034128.1; ENSAPOG00000023403.1.
DR   GeneTree; ENSGT00390000003896; -.
DR   InParanoid; A0A3Q1GUK0; -.
DR   Proteomes; UP000257200; Unplaced.
DR   GO; GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.
DR   GO; GO:0032991; C:protein-containing complex; IEA:UniProt.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0007033; P:vacuole organization; IEA:InterPro.
DR   Gene3D; 1.10.150.780; Vps16, C-terminal region; 1.
DR   InterPro; IPR016534; VPS16.
DR   InterPro; IPR006925; Vps16_C.
DR   InterPro; IPR038132; Vps16_C_sf.
DR   InterPro; IPR006926; Vps16_N.
DR   PANTHER; PTHR12811; VACUOLAR PROTEIN SORTING VPS16; 1.
DR   PANTHER; PTHR12811:SF0; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 16 HOMOLOG; 1.
DR   Pfam; PF04840; Vps16_C; 1.
DR   Pfam; PF04841; Vps16_N; 2.
DR   PIRSF; PIRSF007949; VPS16; 4.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000257200}.
FT   DOMAIN          3..149
FT                   /note="Vps16 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF04841"
FT   DOMAIN          212..263
FT                   /note="Vps16 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF04841"
FT   DOMAIN          396..549
FT                   /note="Vps16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF04840"
SQ   SEQUENCE   687 AA;  77324 MW;  528B417F64C618C0 CRC64;
     MCWSLRDGLR DSLVAAAPYG GPIALLREPL RRSPSSRPQL EIYSASGVGI ASFPWKSGPV
     VHLGWTVSDE LLCIQEDGSV LIYDLFGSFK RHFSMGQEVV QSQVLEAKVF HSPYGTGVAI
     VTGSSRFTLA TNIDDLKLRR LPEVPGNTCL LFRFSGILSG FSWSLFRFSC ILLGFFWSLF
     RFSQILSGFS WVKLQVLVES CSGSTPLQQD PCVLIGELDG VRIISSTNQE LLQEVPLVCQ
     DIFKIASMAP GALLLEAHRE YEVTCLLACA WRVSKCLVLQ AASFGKCFLT DFSPDQFVST
     CRELRVLNAV RESSVGLPLT HAQFKQMTLQ VLIDRLVYRQ FYPLAIEICR YLKIPDYQGV
     SRVLKHWASC KVQQKDLSDE AIARAVCVKV GDSPGVSYSD IAAKAYECGR TELAIKLLDF
     EARSGEQVPL LLKMKRSQLA LSKAVESGDT DLVYTVVNYL KNEMNRGDFF MTLRNQPVAL
     SLYRQFCKLQ EQETLKDLYN QDDNHQELAN YYVTASYKEK RLESRLSLLQ SAVDEYNKAK
     NEFAAKATME ALLALGLHKQ AEQLYRDFRV PDKRYWWLKL KSLAEKEEWE ELEKFSKSKK
     SPIGYLAFVE VCIKCNNKYE AKKYVSKVTP EQKVKAHLAV SDLEGAADAA IERRNEAEMG
     AVLSRCSASD RLVIDRLNRA RAGAAKK
//