ID   A0A3Q1GVC4_9TELE        Unreviewed;       898 AA.
AC   A0A3Q1GVC4;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Cytoplasmic FMR1-interacting protein 1 homolog {ECO:0000313|Ensembl:ENSAPOP00000034393.1};
OS   Acanthochromis polyacanthus (spiny chromis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Acanthochromis.
OX   NCBI_TaxID=80966 {ECO:0000313|Ensembl:ENSAPOP00000034393.1, ECO:0000313|Proteomes:UP000257200};
RN   [1] {ECO:0000313|Ensembl:ENSAPOP00000034393.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the CYFIP family.
CC       {ECO:0000256|ARBA:ARBA00025790}.
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DR   AlphaFoldDB; A0A3Q1GVC4; -.
DR   STRING; 80966.ENSAPOP00000034393; -.
DR   Ensembl; ENSAPOT00000030131.1; ENSAPOP00000034393.1; ENSAPOG00000023658.1.
DR   GeneTree; ENSGT00500000044831; -.
DR   InParanoid; A0A3Q1GVC4; -.
DR   OrthoDB; 446059at2759; -.
DR   Proteomes; UP000257200; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR   GO; GO:0030833; P:regulation of actin filament polymerization; IEA:InterPro.
DR   InterPro; IPR009828; CYRIA/CYRIB_Rac1-bd.
DR   InterPro; IPR008081; Cytoplasmic_FMR1-int.
DR   PANTHER; PTHR12195:SF4; CYTOPLASMIC FMR1-INTERACTING PROTEIN 1; 1.
DR   PANTHER; PTHR12195; CYTOPLASMIC FMR1-INTERACTING PROTEIN-RELATED; 1.
DR   Pfam; PF07159; CYRIA-B_Rac1-bd; 1.
DR   Pfam; PF05994; FragX_IP; 1.
DR   PIRSF; PIRSF008153; FMR1_interacting; 1.
DR   PRINTS; PR01698; CYTOFMRPINTP.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000257200}.
FT   DOMAIN          64..268
FT                   /note="CYRIA/CYRIB Rac1 binding"
FT                   /evidence="ECO:0000259|Pfam:PF07159"
SQ   SEQUENCE   898 AA;  104557 MW;  8073F14F94EED4EE CRC64;
     MASTVTLEDA LSNVDLLEEL PLPDQQPCIE PLPSSVMYQP NFNTNFEDRN AFVTGIARYI
     EQATVHSSMN DMLEEGQEYA IMLYTWRSCS RAIPQVKCNE QPNRVEIYEK TVEVLEPEVT
     KLMNFMYFQR TAIDRFCGEV RRLCHTERRK DFVSEAYLLT LGKFINMFAV LDELKNMKCS
     VKNDHSAYKR AAQFLRKMSE PSSIQESQNL SMFLANHNKI TQSLQQQLEV INGYEELLAD
     IVNLCVDYYD NKLYLTPSEK HMLLKVMGFG LYLMDGNSSN IYKLDAKKRI NLTKIDKFFK
     QLQVVPLFGD MQIELSRYIK TSAHFEDNKS RWTCTSISSS PQYNICEQMI QIREDHMRFI
     SELARYSNSE VVTGSGRQEA QKTDSEYRKL FDLALQGMQL LSQWSAHVME VYSWKLVHPT
     DKYSNKECPD NAEEYERATR YNYTSEEKFA LVEVIAMIKG LQVLMGRMES VFNHAIRHTI
     YSALQDFAQV TLRDPLRQAI KKKKNVIQSV LQAIRKTVCD WETGREPHND PALRGEKDPK
     GGFDIKVPRR AVGPSSTQLY MVRTMLESLI ADKSGSKKTL RSSLEGPTIL DIEKFHRESF
     FYTHLLNFSE TLQQCCDLSQ LWFREFFLEL TMGRRIQFPI EMSMPWILTD HILETKEASM
     MEYVLYPLDL YNDSAHYALT KFKKQFLYDE IEAEVNLCFD QFVYKLADQI FAYYKILAGS
     LLLDKRLRSD CKNQGANIPW PASNRYETLL KQRHVQLLGR SIDLNRLISQ RVSAALYKSL
     ELAINRFESE DLTSIMELDG LLEINRMTHK LLSKFLTLDS LDAMFREANH NVSAPYGRIT
     LHVFWELNYD FLPNYCYNGS TNRFVRTILP FSQEFQRDKP PNAQPHYLYG SKVSTVCL
//