ID   A0A3Q1H2D1_ANATE        Unreviewed;      1558 AA.
AC   A0A3Q1H2D1;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=SH3 domain and tetratricopeptide repeats 2 {ECO:0000313|Ensembl:ENSATEP00000001664.1};
GN   Name=SH3TC2 {ECO:0000313|Ensembl:ENSATEP00000001664.1};
OS   Anabas testudineus (Climbing perch) (Anthias testudineus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Anabantaria; Anabantiformes; Anabantoidei; Anabantidae; Anabas.
OX   NCBI_TaxID=64144 {ECO:0000313|Ensembl:ENSATEP00000001664.1, ECO:0000313|Proteomes:UP000265040};
RN   [1] {ECO:0000313|Ensembl:ENSATEP00000001664.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   Ensembl; ENSATET00000001686.2; ENSATEP00000001664.1; ENSATEG00000001211.2.
DR   GeneTree; ENSGT00530000063812; -.
DR   Proteomes; UP000265040; Unplaced.
DR   Gene3D; 2.30.30.40; SH3 Domains; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 4.
DR   InterPro; IPR036028; SH3-like_dom_sf.
DR   InterPro; IPR001452; SH3_domain.
DR   InterPro; IPR042772; SH3TC1/SH3TC2.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR22647:SF2; SH3 DOMAIN AND TETRATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 2; 1.
DR   PANTHER; PTHR22647; SH3 DOMAIN AND TETRATRICOPEPTIDE REPEATS CONTAINING PROTEIN; 1.
DR   Pfam; PF07653; SH3_2; 1.
DR   Pfam; PF13181; TPR_8; 1.
DR   SMART; SM00326; SH3; 2.
DR   SMART; SM00028; TPR; 8.
DR   SUPFAM; SSF50044; SH3-domain; 2.
DR   SUPFAM; SSF48452; TPR-like; 3.
DR   PROSITE; PS50002; SH3; 2.
DR   PROSITE; PS50005; TPR; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000265040};
KW   SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW   ProRule:PRU00192}; TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT   DOMAIN          217..281
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
FT   DOMAIN          309..372
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
FT   REPEAT          1227..1260
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REGION          1..66
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          434..480
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1355..1449
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1464..1558
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..21
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        442..478
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1361..1383
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1390..1406
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1490..1504
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1558 AA;  176064 MW;  56D24C9094457833 CRC64;
     MRNELRGENR QQHRDISPAE LDALWREPPY TLGGTNEHFP GNDIMTQGAG EEEDGPVVES
     GEGGEEPDNY WKKKEAFLRG STVSLGDKFS SEIVLLFTGQ RRSSANPDRA LQEALRTRLR
     VVESNSKDVS QLFKDLSARL VSVHAEKDSF VLTFKTVEEI WKFSTYLALG FVTRCLENFL
     CDQAFWLDSE LLSDLEISVT VDEEHLATLY LGLVLQEGCF FAKALFTRSG QDEDDEDQLS
     FKKNDLLMVK DTGQDNMWEG TMLSTGNHGL VPVNAMQPLP YPFYQWFLRK YTGYAGCSPT
     EKEPYVHPIV TGSCVAVVDY SPVGLDELQL SQGDIVEIQG LLVRGLDVFI GTHSSTGHTG
     FVHKAHVKPL DTTPLDEQLV FLTEEERASL AQIDLSNSEP SNIGLLETLF SSDISSVYRL
     DRLDETDFMY IRSRPKHDKV PTSTRQSVMS EKSGGTPPYH SSPRPSLSHS SPRVSLYQSH
     NPLPLEGEHL SFSLDDTFRE LDEFHEDPPL FLEENSWEGE ESELSDPTLT LLNHQHFLED
     YLPLYDLQYS FMWVTFTGKT EGELSGHLES IRETAKRMGM HWAHRRACFL LGRLCARKLK
     FSQARVYYEE ALSICVDSFS DTPLLVALFT NLTSVYLKQR MTDKLPQTLE KASALLLCLP
     RHNFTSTDEM ELLKLLLRRS VVIGDKHLEA RVCYLISSLF LLLRKSDDAL PFVERLQFLS
     VTLSATEGRP IVPLDLNWLL SWLYHRKYMP YLALASLSLD TRHDHSLHEA FQRIGLFIKN
     SVRLNPCWKE GSSLLPAQIV IYLQQALAIA EQGADMKTQR DLCLGLASVY QQHGSLDKAV
     RCAQQAVERG GHINEEEGFE ASVLLGWLLV LTGQVDQAQS VLHPLLTSLQ GTDSPTQRGV
     IHNLLSLCLR RQGRVQEAGW HLYSALVISR ENGNQRNQAL ALANLGCLAL DVGASMIAER
     FLVRSLHLFL DLWESYTDVE HVQTYLWLGR SYKDRGRSQD SRASYEMGLL IALHARNLHS
     QMVVAKVLSR LYAEMLLYGQ SIAYYEHCVS VSRELKDKRL EGEYLEILSS LYLSLNTEKS
     SRKSLDYTKQ SLRISIDLGK REEESETWLQ VGRIYYLIQE DELADMYLQA AVKTALRMND
     PHFAMSIYEE AGDVYFKGHR NRIASLPFYR DGSLPFARSI KDIHSEFRLL SKLTELLMNQ
     GEQEEALQYA TLAVQIASKT GVRVNERSAF HRLASVYYSL QQYEMAENYY LKSLSLCPPL
     LQHPMEARYY TKVYCRLGNL TLHKLKDAFD AVGYFQLALA AALEDQANPE ALYVVYMKLA
     EIHGNHMPDA HMCQVYRDRA QDLKRVLAGG ESSAVGREYV NDAHTESDQK KENESDDNIG
     RTEIENDILN STPEAKKYED DSPSQAFIHV DAESKCTDTN SGSTDVKEDT DGPSADASET
     HTAVSQSYSD SIFTESFDTA KEQISDFSSS TDTLQSHQKP TDVKDSDFDA DQSTPSQIPL
     NHSSDITGHA DARETDSDIQ DEQNSLSEET NAKSDPVQKE VRGEDNRVSL SVQTSTKL
//