ID A0A3Q1H4M2_ANATE Unreviewed; 854 AA.
AC A0A3Q1H4M2;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Sorting nexin-14-like {ECO:0000313|Ensembl:ENSATEP00000003242.2};
OS Anabas testudineus (Climbing perch) (Anthias testudineus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Anabantaria; Anabantiformes; Anabantoidei; Anabantidae; Anabas.
OX NCBI_TaxID=64144 {ECO:0000313|Ensembl:ENSATEP00000003242.2, ECO:0000313|Proteomes:UP000265040};
RN [1] {ECO:0000313|Ensembl:ENSATEP00000003242.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the sorting nexin family.
CC {ECO:0000256|ARBA:ARBA00010883}.
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DR AlphaFoldDB; A0A3Q1H4M2; -.
DR Ensembl; ENSATET00000003271.2; ENSATEP00000003242.2; ENSATEG00000002189.2.
DR GeneTree; ENSGT00950000182856; -.
DR Proteomes; UP000265040; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IEA:InterPro.
DR CDD; cd06877; PX_SNX14; 1.
DR CDD; cd08722; RGS_SNX14; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR Gene3D; 1.10.167.10; Regulator of G-protein Signalling 4, domain 2; 1.
DR InterPro; IPR003114; Phox_assoc.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR016137; RGS.
DR InterPro; IPR036305; RGS_sf.
DR InterPro; IPR044926; RGS_subdomain_2.
DR InterPro; IPR037436; SNX14_PX.
DR InterPro; IPR037892; SNX14_RGS.
DR InterPro; IPR013937; Sorting_nexin_C.
DR PANTHER; PTHR22775; SORTING NEXIN; 1.
DR PANTHER; PTHR22775:SF44; SORTING NEXIN-14; 1.
DR Pfam; PF08628; Nexin_C; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF02194; PXA; 1.
DR Pfam; PF00615; RGS; 1.
DR SMART; SM00312; PX; 1.
DR SMART; SM00313; PXA; 1.
DR SMART; SM00315; RGS; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR SUPFAM; SSF48097; Regulator of G-protein signaling, RGS; 1.
DR PROSITE; PS50195; PX; 1.
DR PROSITE; PS51207; PXA; 1.
DR PROSITE; PS50132; RGS; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000265040};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..29
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 59..226
FT /note="PXA"
FT /evidence="ECO:0000259|PROSITE:PS51207"
FT DOMAIN 258..390
FT /note="RGS"
FT /evidence="ECO:0000259|PROSITE:PS50132"
FT DOMAIN 473..593
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
SQ SEQUENCE 854 AA; 98663 MW; CD527BE814AAE8E5 CRC64;
LSLCVSVSFL YIHILMIFWS FLAGVITFYC SLGPESLLPN ILFTIKPRNK VSQVSLNSMG
FTCTEICAVC GKVKCKRHRP TLLLENYQPW LDLKVHSKVD ASVAEVDIPA VFADKVMKAA
LKHIEIIAKA REKVKNVEGL QLAALDEYGA DLHVALHSRK DELRYLRKLT EMLFPYVMPP
KSTDCRSLAL LLREVMAGSV ILPTMDFMAD PDTVNLMVLI FVDDTPPEPA TEPPSAMVPF
LQKYADVSNK KQSVLKLELK EIRKQQDLLF RFMNFLKQEG AVHVLQFCLA VEEFNDRILR
PELSDSELQR LHGEVLHMYE TYCLDESIDK INFDLMIVEQ IRNIAKGPHT GVVKLQTMPC
LFEAYEHVLF LLEKVFTPMF CHSDEYFRYL LRGAESPTRN SRINRNLSKR GESFGISRIG
SKIKGVFKST TMDGAILPPS AMNDVEEATV VMEDDSPAEP TSTQGTQRNL LAWSIAIPYI
DFYEDETKRE KVPVFCIEVE RNDRKEVGHE PESWAVYRRY LEFYVLESKL TEFHGTFADA
QLPSKRIIGP KNYEFLESKR EEFEEYLQRL LQHPELSNSQ LLADFLSPHS MESQFLDRML
PDVNLGKIFK SVPGKLIKEK GQNLEPFIQS FFNSCESPKP KPSRPELTIL SPSAENNKKL
FNSLFKNNAN LPESSEKRHN PNYFMEMVTV HGMYDYMMNI GRVVFHMSDY LHHFLSAGRI
LFKNTFEAYM DQYMQSKLEH ILQEHRMVSL ITQLRDAVFC ENSVERTTED KQVRAKQTFE
EMMKYLPDFV GKCIGDEVKY EGIRLLFDGL QQPLLNKQMT YVLLDIAVQE LFPEITKVNE
WEEENVKKEH RHVQ
//
