ID A0A3Q1HBQ7_ANATE Unreviewed; 674 AA.
AC A0A3Q1HBQ7;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Prospero homeobox 2 {ECO:0000313|Ensembl:ENSATEP00000002303.1};
OS Anabas testudineus (Climbing perch) (Anthias testudineus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Anabantaria; Anabantiformes; Anabantoidei; Anabantidae; Anabas.
OX NCBI_TaxID=64144 {ECO:0000313|Ensembl:ENSATEP00000002303.1, ECO:0000313|Proteomes:UP000265040};
RN [1] {ECO:0000313|Ensembl:ENSATEP00000002303.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR AlphaFoldDB; A0A3Q1HBQ7; -.
DR Ensembl; ENSATET00000002327.2; ENSATEP00000002303.1; ENSATEG00000001654.2.
DR GeneTree; ENSGT00940000154790; -.
DR InParanoid; A0A3Q1HBQ7; -.
DR OMA; SPQQRMC; -.
DR OrthoDB; 2877587at2759; -.
DR Proteomes; UP000265040; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0048468; P:cell development; IEA:UniProt.
DR GO; GO:0007399; P:nervous system development; IEA:UniProt.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 1.10.10.500; Homeo-prospero domain; 1.
DR InterPro; IPR023082; Homeo_prospero_dom.
DR InterPro; IPR037131; Homeo_prospero_dom_sf.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR039350; Prospero_homeodomain.
DR PANTHER; PTHR12198; HOMEOBOX PROTEIN PROSPERO/PROX-1/CEH-26; 1.
DR PANTHER; PTHR12198:SF9; PROX2 PROTEIN; 1.
DR Pfam; PF05044; HPD; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS51818; HOMEO_PROSPERO; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000265040};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 520..674
FT /note="Prospero"
FT /evidence="ECO:0000259|PROSITE:PS51818"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 73..117
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 132..196
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 320..363
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 73..102
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 140..172
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 674 AA; 76349 MW; 05B6E80E8C55E35C CRC64;
MNLSLPDQNM HSSSEGCLDD DKPDIMLPCF RRNMYDEPLT SYSNGSIISQ LLRKTIHNKR
TLDESHFYLS STTAADSGQE DQSSVSSKDS IAEASSPSGH ISIGASPEGE HPMTDHMQAK
RARVENIIRV MAGSPNSRQH GDSERSDTDG KDTREAREAY RENKRKQRLP QHQDHSVGGP
VSRRPGSSSS DTCNTKDEEC HKLKEQLHSM QRLLRQLQEK FLQVYSQEEP EHDSRDEMEV
AIEHDTLGET TDTYYVGTGD DFERKNSRVT VDCRDRMKEV SYVVHQRESH NLQETLKQEL
SRAVNECVDK VFKKVSSKGL ELSPGSRMCS SPEMQLSMGA DRKSKHADST QEQPPAGEAA
LKPRSLEYYE STEAQSSQDQ TEALSLVVRK PAVTPLSSVT PSVKRPYPVH QTPFQFNYGT
PLHDSQILEH LLKYGPHSNF GALPCMPPSM DRTSPDSVDL PWDSIAMRSK VTSSHLTHHA
RASALGAVTV DNLCLPHVKI ECGELQSMAE RNPYLSLNIQ EGLTPSHLKK AKLMFFYTRY
PSSNVLKTFF PDVKFNRCIT SQLIKWFSNF REFYYIQMEK FARQAMVDGI SDVKDITVSR
DSELFRALNM HYNKANDFHV PDRFLEVAEI TLHEFYNAIA AAKDSDPSWK KAIYKVICKL
DSDVPEEFKT SSYL
//
