ID A0A3Q1HG55_ANATE Unreviewed; 958 AA.
AC A0A3Q1HG55;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=BCAR1 scaffold protein, Cas family member {ECO:0000313|Ensembl:ENSATEP00000006349.2};
OS Anabas testudineus (Climbing perch) (Anthias testudineus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Anabantaria; Anabantiformes; Anabantoidei; Anabantidae; Anabas.
OX NCBI_TaxID=64144 {ECO:0000313|Ensembl:ENSATEP00000006349.2, ECO:0000313|Proteomes:UP000265040};
RN [1] {ECO:0000313|Ensembl:ENSATEP00000006349.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell junction, focal adhesion
CC {ECO:0000256|ARBA:ARBA00004246}.
CC -!- SIMILARITY: Belongs to the CAS family. {ECO:0000256|ARBA:ARBA00007848}.
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DR AlphaFoldDB; A0A3Q1HG55; -.
DR Ensembl; ENSATET00000006453.2; ENSATEP00000006349.2; ENSATEG00000004489.2.
DR GeneTree; ENSGT00950000183008; -.
DR OrthoDB; 2902504at2759; -.
DR Proteomes; UP000265040; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR CDD; cd11552; Serine_rich_BCAR1; 1.
DR Gene3D; 1.20.120.230; Alpha-catenin/vinculin-like; 1.
DR Gene3D; 1.20.120.830; Serine-rich domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR021901; CAS_C.
DR InterPro; IPR037362; CAS_fam.
DR InterPro; IPR014928; Serine_rich_dom.
DR InterPro; IPR038319; Serine_rich_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR10654:SF15; BREAST CANCER ANTI-ESTROGEN RESISTANCE PROTEIN 1; 1.
DR PANTHER; PTHR10654; CAS SCAFFOLDING PROTEIN; 1.
DR Pfam; PF12026; CAS_C; 1.
DR Pfam; PF08824; Serine_rich; 1.
DR Pfam; PF00018; SH3_1; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50002; SH3; 1.
PE 3: Inferred from homology;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Cell junction {ECO:0000256|ARBA:ARBA00022949};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000265040};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 1..63
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 144..225
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 264..283
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 472..505
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 695..730
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 799..823
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 182..223
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 804..821
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 958 AA; 105394 MW; 7119EE8D0AF9FC8B CRC64;
KSNVLAKALF DNVAESPDEL SFRKGDIMTV LERDTQGLDG WWLCSLHGRQ GIVPGNRLKI
LVGMYDSKQQ QQATPSTPDL AACPVSQVQR PLPSQSTYTK PAPALSTTAI ATSSTGFANK
PLPTAQYTSM HPAYSIPSAA QPNPDSVYMM PPSHAPKPSP QSLYQVPAGP SGPPSQAQPG
PPSKAPALSQ RQYQLPVQDI YQVPPSVSPG QLQGPSTAGG TGAGQDVYQV PPSLDKRSNK
SLGKVVVPTR VGQVYVYDTM KSDQDEYDIP PRHPPLPQHD IYDVPPTRQQ YITQVYDTPP
MVVKGPSGGQ EIYDTPAGTD KNMQQTVYDF PPSVSKDIPD GQPFREETYD VPPHFAKLRP
QLPVPPQYSH NNLNDDEEPP ILEDVYDVPP PILTDKLYHR DRGGVIQAPQ EIYDIPANLR
TAGHPTQDVY DFPREREERV GEREDNYVYD VPPQVVRDAQ STSEELTMSF KRLSASSTGS
TRSNHSASSL DMVPVRDSSS SSSLLTPGSI ASKPLLLDLE QAMERLSRLQ QAVESSVSLM
MSYIEGNWRS PTHLEGNLPA IHQAADRVRN TVRDFLEFAR GAVANAAQAT DRSLQTKLGR
QVGKMEEVFQ SLIRHSQSLD AISWSPAALT APPPGGDDLD RLIMTARGIP DDAKQLASFL
HGNASLLFKR TNRQQQQLPL PPIPGEISGH MTGSGSGTYQ GGEKVSIQSR PLPSPPKFTA
AEEEEGVDRP YETTEEGWME DYDYVHLQGK EEFEKNQRQL LEKGNIIRHN KAQLEQQQIK
QFERLEQEVS QPINNDMTGW VPSPHHPSAN QLSQNGSGGP SSKLCHGDRQ LLLFYQEQCE
QNITTVTNAI DAFFTAVNSN QPPKIFVAHS KFVILSAHKL VFIGDTLSRQ AKSPEVRARV
AQSSNTLCEK LKDIVISTKT AALQYPSPGA AREMTERVKE LAGCTQQFKM VLGQLLVM
//
