ID   A0A3Q1HJF6_ANATE        Unreviewed;       668 AA.
AC   A0A3Q1HJF6;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   02-JUN-2021, sequence version 2.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE            EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
OS   Anabas testudineus (Climbing perch) (Anthias testudineus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Anabantaria; Anabantiformes; Anabantoidei; Anabantidae; Anabas.
OX   NCBI_TaxID=64144 {ECO:0000313|Ensembl:ENSATEP00000007590.2, ECO:0000313|Proteomes:UP000265040};
RN   [1] {ECO:0000313|Ensembl:ENSATEP00000007590.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC         Evidence={ECO:0000256|ARBA:ARBA00001556};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A3Q1HJF6; -.
DR   Ensembl; ENSATET00000007717.2; ENSATEP00000007590.2; ENSATEG00000005292.2.
DR   GeneTree; ENSGT00940000156142; -.
DR   Proteomes; UP000265040; Unplaced.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR   CDD; cd17980; DEXHc_DHX35; 1.
DR   CDD; cd18791; SF2_C_RHA; 1.
DR   Gene3D; 1.20.120.1080; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR   InterPro; IPR048333; HA2_WH.
DR   InterPro; IPR007502; Helicase-assoc_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR   PANTHER; PTHR18934:SF136; ATP-DEPENDENT RNA HELICASE DHX35-RELATED; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF21010; HA2_C; 1.
DR   Pfam; PF04408; HA2_N; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF07717; OB_NTP_bind; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00847; HA2; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265040};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..16
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           17..668
FT                   /note="RNA helicase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5030079484"
FT   DOMAIN          31..196
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          228..405
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
SQ   SEQUENCE   668 AA;  74964 MW;  0742C8E836E8587D CRC64;
     MCSSVCLCVI LMAVNALFCV LSPIQHRNNI LYLVESYQTV IIVGETGCGK TTQIPQYLLE
     AGWAAEGKVI GVTQPRRVAA ISVANRVAEE RGALLGHEVG YTIRFDDCCD PHATRIKFLT
     DGMLVREMMA DPLLKKYSVL MLDEAHERTL YTDIAIGLLK KIQKKRRDLR VIVASATLDA
     KKFHDFFNLN ESGDPVKDTC GILTVEGRTF PVDIFYTVSP VPDYVKATVE TVLKIHETEE
     DGDVLAFLTG QEEVEKVVSL LQDQARSLSR YGMKKHLRIL PMYSGLPYAE QMKVFERAPS
     SVRKVVVATN IAETSITING IVFVIDCAFV KLRAYNPRTA IESLLVTPIS KASASQRAGR
     AGRNRPGKCF RLYTEEDFEK LPASTVPEMQ RTNLASVILQ LKALGIDNVL RFSFLSPPPA
     QTMVQALELL YALGGLDHYG RLTDPMGVRM AEFPLSPMFA KMLLESGNFG CSKEIVTIAA
     MMQIQNIFSV PPNQKKVAAR EHRKFAVAEG DHLTMLNVYE AFIKHQKSSQ WCQEHFLNYK
     GLLRAVTVRE QLRRLMNKFK VPRTSSEGDP DVILKCIVSG FFANAARIHH SGSYRTLRDD
     RELHIHPNSV LFGEKPPKWV VFNEVVQTAK YYMRDVTAVE SSWLVELAPH FYKQAKHGSL
     ASKRSRVL
//