ID A0A3Q1HK32_ANATE Unreviewed; 682 AA.
AC A0A3Q1HK32;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Rhophilin, Rho GTPase binding protein 1 {ECO:0000313|Ensembl:ENSATEP00000005373.1};
GN Name=RHPN1 {ECO:0000313|Ensembl:ENSATEP00000005373.1};
OS Anabas testudineus (Climbing perch) (Anthias testudineus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Anabantaria; Anabantiformes; Anabantoidei; Anabantidae; Anabas.
OX NCBI_TaxID=64144 {ECO:0000313|Ensembl:ENSATEP00000005373.1, ECO:0000313|Proteomes:UP000265040};
RN [1] {ECO:0000313|Ensembl:ENSATEP00000005373.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the RHPN family.
CC {ECO:0000256|ARBA:ARBA00010369}.
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DR AlphaFoldDB; A0A3Q1HK32; -.
DR Ensembl; ENSATET00000005464.2; ENSATEP00000005373.1; ENSATEG00000003810.2.
DR GeneTree; ENSGT00940000153837; -.
DR OrthoDB; 24567at2759; -.
DR Proteomes; UP000265040; Unplaced.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd11633; HR1_Rhophilin-1; 1.
DR CDD; cd00992; PDZ_signaling; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 1.25.40.280; alix/aip1 like domains; 1.
DR Gene3D; 1.10.287.160; HR1 repeat; 1.
DR InterPro; IPR004328; BRO1_dom.
DR InterPro; IPR038499; BRO1_sf.
DR InterPro; IPR011072; HR1_rho-bd.
DR InterPro; IPR036274; HR1_rpt_sf.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR047138; RHPN1_2.
DR PANTHER; PTHR23031; RHOPHILIN; 1.
DR PANTHER; PTHR23031:SF6; RHOPHILIN-1; 1.
DR Pfam; PF03097; BRO1; 1.
DR Pfam; PF02185; HR1; 1.
DR Pfam; PF00595; PDZ; 1.
DR SMART; SM01041; BRO1; 1.
DR SMART; SM00742; Hr1; 1.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF46585; HR1 repeat; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR PROSITE; PS51180; BRO1; 1.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS51860; REM_1; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01207, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000265040}.
FT DOMAIN 41..115
FT /note="REM-1"
FT /evidence="ECO:0000259|PROSITE:PS51860"
FT DOMAIN 126..475
FT /note="BRO1"
FT /evidence="ECO:0000259|PROSITE:PS51180"
FT DOMAIN 531..595
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 1..36
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 92..119
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 682 AA; 76682 MW; A40B7B32F4DBB935 CRC64;
MEEPATREFD LSLSDGASDD DMPLTLPTES SLSGSIRKGC DPFAQTQRSK LQHRRARINQ
QINKEMRMRA GAENLFRATT NNKVKETVAL ELSFVNSNLQ LLKEELEELN SNMEVYQTDS
EAVNVPLIPL GLKETKEMDF TVAIEDFICE HYGEDSSPYD KEIKELMELR QAMRTPSRNQ
AGLELLMEYY NQLYYLDQRF FPPHRNLGVH FHWYDSLTGV PSSQRALAFE KGSVLFNIGA
LYTQIGARQD RSATAGIDRA IDAFQRAAGA FNYLKENFSN APSLDMSGPS LCMLVRLMVA
QVQECVFERV TLTTQDTSFT SQLCLAQEAA RVSDVYLLVQ QTMTQPLMKD YVPFSWVSMV
QVKSEHFRAL SHYYAAVALC DHVSTPEEVD EEAEKTFLQF YVSTPAGASL SQVLRDPEKR
RKLGKAHLRR AVIRHEEALR VHGLCKILRK MDILQDVLSL THKRSLDKYS ELDREDDFDE
TAEAPEIQSH TQQKPDVTSP NFSTVQVTDI FQRLGPLSVF CARARWGPVR VISLQRGEGG
LGLTLRGDSP VLVAGVVPGG CAAEAGLREG DYIVAVDGQD CKWAKHGEVV HMLKSCSDRG
VELRVVTLHS HDTQVERRAI MVSHSDKENT RQRLLSGAKG QSSASLLNWN RKKKREGSGI
TKRLGSTFSL SFGSIRDSEA MY
//
