ID   A0A3Q1HNV2_ANATE        Unreviewed;       300 AA.
AC   A0A3Q1HNV2;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   02-JUN-2021, sequence version 2.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Tumor suppressor candidate 3 {ECO:0000313|Ensembl:ENSATEP00000010507.2};
OS   Anabas testudineus (Climbing perch) (Anthias testudineus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Anabantaria; Anabantiformes; Anabantoidei; Anabantidae; Anabas.
OX   NCBI_TaxID=64144 {ECO:0000313|Ensembl:ENSATEP00000010507.2, ECO:0000313|Proteomes:UP000265040};
RN   [1] {ECO:0000313|Ensembl:ENSATEP00000010507.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC       {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004477}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the OST3/OST6 family.
CC       {ECO:0000256|ARBA:ARBA00009561}.
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DR   AlphaFoldDB; A0A3Q1HNV2; -.
DR   Ensembl; ENSATET00000010690.2; ENSATEP00000010507.2; ENSATEG00000007378.2.
DR   GeneTree; ENSGT00390000012030; -.
DR   UniPathway; UPA00378; -.
DR   Proteomes; UP000265040; Unplaced.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
DR   CDD; cd02947; TRX_family; 1.
DR   Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR   InterPro; IPR021149; OligosaccharylTrfase_OST3/OST6.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   PANTHER; PTHR12692; DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE-RELATED; 1.
DR   PANTHER; PTHR12692:SF1; TUMOR SUPPRESSOR CANDIDATE 3; 1.
DR   Pfam; PF04756; OST3_OST6; 2.
DR   SUPFAM; SSF52833; Thioredoxin-like; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265040};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        164..183
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        195..217
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        223..243
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        270..290
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   300 AA;  34439 MW;  EF1E7D935F0BB7F6 CRC64;
     MSSLPFSCLY VQNLLSEKVE QMMEWSSRRS VVRMNGDKFR RFVKAPPRNY SVIVMFTALQ
     PQRQCSVCRQ ANEEYQVLAN SWRYSSAFSN KLFFTVVDYD EGADVFQQLN MNSAPTFMHF
     PAKGKPKRAD TFDLQRIGFA SEQLAKWIAD RTDVQIRVFR PPNYSGTIAL ALLVSLVGGL
     LYLRRNNLEF IYNKTGWAMA ALCVVFAMTS GQMWNHIRVA HPIYIHAFTI HFFVLCYFLN
     NLVPDAAITM GMVLLNEAAT SKGDVGKRRI ICLVGLGLVV FFFSFLLSIF RSKYHGYPYR
//