ID A0A3Q1HQF5_ANATE Unreviewed; 310 AA.
AC A0A3Q1HQF5;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Ventral anterior homeobox 1 {ECO:0000313|Ensembl:ENSATEP00000007298.1};
OS Anabas testudineus (Climbing perch) (Anthias testudineus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Anabantaria; Anabantiformes; Anabantoidei; Anabantidae; Anabas.
OX NCBI_TaxID=64144 {ECO:0000313|Ensembl:ENSATEP00000007298.1, ECO:0000313|Proteomes:UP000265040};
RN [1] {ECO:0000313|Ensembl:ENSATEP00000007298.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
CC -!- SIMILARITY: Belongs to the EMX homeobox family.
CC {ECO:0000256|ARBA:ARBA00007397}.
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DR AlphaFoldDB; A0A3Q1HQF5; -.
DR STRING; 64144.ENSATEP00000007298; -.
DR Ensembl; ENSATET00000007422.2; ENSATEP00000007298.1; ENSATEG00000005127.2.
DR GeneTree; ENSGT00940000161152; -.
DR InParanoid; A0A3Q1HQF5; -.
DR OMA; ASEDCNK; -.
DR OrthoDB; 903523at2759; -.
DR Proteomes; UP000265040; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR000047; HTH_motif.
DR PANTHER; PTHR24339; HOMEOBOX PROTEIN EMX-RELATED; 1.
DR PANTHER; PTHR24339:SF32; VENTRAL ANTERIOR HOMEOBOX 1; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR PRINTS; PR00031; HTHREPRESSR.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 3: Inferred from homology;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000265040};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 89..149
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 91..150
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 1..58
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 199..238
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 28..55
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 310 AA; 33575 MW; BF2DADC5283C5EFE CRC64;
MEVRYNQETE GMVLKNGLKE GKEGKDSQGS LSKSFLKEQQ DSFSPSGTVD NCEKNRGSTG
DPDYCRRILV RDAKGSIREI ILPKGLDLDR PKRTRTSFTA EQLYRLEMEF QRCQYVVGRE
RTELARQLNL SETQVKVWFQ NRRTKQKKDQ GKDSELRSVV SETAATCSVL RLLEQGRLLT
PPGLPGLLPH CGSSTLGSAL RPPSMAMASN GSSSSGSSST AGSSPPLPTA TSSGTAAALQ
TSPAAHSLFS FPMPSLLSGV TGRISTNPLS MAGSLAGNLQ ELSARYLSSS AFEPYSRTNG
KETVDKKILE
//
