ID   A0A3Q1HVX4_ANATE        Unreviewed;      1044 AA.
AC   A0A3Q1HVX4;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   02-JUN-2021, sequence version 2.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=PDZ domain containing RING finger 3b {ECO:0000313|Ensembl:ENSATEP00000011990.2};
OS   Anabas testudineus (Climbing perch) (Anthias testudineus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Anabantaria; Anabantiformes; Anabantoidei; Anabantidae; Anabas.
OX   NCBI_TaxID=64144 {ECO:0000313|Ensembl:ENSATEP00000011990.2, ECO:0000313|Proteomes:UP000265040};
RN   [1] {ECO:0000313|Ensembl:ENSATEP00000011990.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3Q1HVX4; -.
DR   Ensembl; ENSATET00000012186.2; ENSATEP00000011990.2; ENSATEG00000008337.2.
DR   GeneTree; ENSGT00950000183062; -.
DR   Proteomes; UP000265040; Unplaced.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
DR   CDD; cd00992; PDZ_signaling; 2.
DR   Gene3D; 2.30.42.10; -; 2.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR   InterPro; IPR001478; PDZ.
DR   InterPro; IPR036034; PDZ_sf.
DR   InterPro; IPR003613; Ubox_domain.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   InterPro; IPR017907; Znf_RING_CS.
DR   PANTHER; PTHR15545:SF5; E3 UBIQUITIN-PROTEIN LIGASE PDZRN3; 1.
DR   PANTHER; PTHR15545; PDZ DOMAIN CONTAINING RING FINGER PROTEIN 3, 4; 1.
DR   Pfam; PF00595; PDZ; 2.
DR   Pfam; PF13923; zf-C3HC4_2; 1.
DR   SMART; SM00228; PDZ; 2.
DR   SMART; SM00184; RING; 1.
DR   SMART; SM00504; Ubox; 1.
DR   SUPFAM; SSF50156; PDZ domain-like; 2.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   SUPFAM; SSF49599; TRAF domain-like; 1.
DR   PROSITE; PS50106; PDZ; 2.
DR   PROSITE; PS00518; ZF_RING_1; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265040};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00175}.
FT   DOMAIN          18..54
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50089"
FT   DOMAIN          261..333
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   DOMAIN          415..489
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   REGION          541..594
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          735..846
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        557..582
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        747..795
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        819..833
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1044 AA;  118101 MW;  752E462FD42AA68D CRC64;
     MGFELDRFKG TVDPDFKCNL CNKVLEDPLT TPCGHVFCSG CVLPWVVQQS SCPVKCQRIS
     AKELNHVLPL KNLILKLEIK CDNYARGCDA VVKLQHLAEH AEMCEYTPAK CRNKGCNDVL
     NLRDMDAHMR ETCDYRAVGI CESGCGLMLT HKEQKFNGHC CLRALKAHNS ALQCKMLSLD
     REFKKQTIKA NKREKELLAQ LSAVHSELQV TALKYQKKFT EYSERIDSLT KTVAFSCKVS
     NKVSAVREHK WIQPLSLEVL FSAPDDNDST SNEGIFVSKI IENGPADKEG GLQIHDRIIE
     VNGKDLSKAT HDQAVEAFRT AKEPIMVQVL RRAPHPKLVT SAIDTEVSDI STQTDITLQH
     IMALTKLPPS SPPMTELEEY LLPEEHPPGH AYFDPNDFLE GIQQDIEREE LEYEEVDLYR
     ANIQDKLGLT ICYRTDDEDE AGIYISEIDP NSIAAKDGRI REGDKIIQIN GVEIQNREDA
     VALLTSEGNQ NISLLVARPE IQLDEGWMDD DRNDFLDDLH MDMLEQQHHQ AMQFTASMLQ
     QKKHEEDGGT TDTATLLSNH HEKDSGVGRT DESTRNDESS EQENLGDDQT TASNTLGSCR
     KLTYSQDTLG STDLPFSSES FISADNADTD FLGIPADECE RFRELLELKC QMRSGAAQSL
     YYQGVGAEGQ DQEGVDKELE LLNEELRTIE LECLNIVRAH KMQQLREQCR ESWMLHNSGF
     RNYNTSIDAR RHELSDITEL PEKSDKDSSS AYNTGESCRS TPLTLELSPD NSLRRGAENQ
     GTAGTSSSNS RMLKPLLSPV QEACGPSRSR GCPKDLDGVL PAEGKERKLG ESSKSSRGFS
     QPHSPYKHAH IPAHAQHYQS YMQLIQQKSA VEYAQSQMSL VSMCRDPISP SDLEPKMEWK
     VKIRSDGTRY ITKRPVRDKL LRERALRIHE ERSGMTTDDD AISELKMGRY WSKEERKQHA
     VRAKEQRLRR EFMKQSRADC LKEQAAPEDK KEPNIIELSH KKMMKKRNKK IFDNWMTIQE
     LLTHGTKSPD GTRVYNSLLS VTTV
//