ID A0A3Q1IDU2_ANATE Unreviewed; 685 AA.
AC A0A3Q1IDU2;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Connector enhancer of kinase suppressor of Ras 1 {ECO:0000313|Ensembl:ENSATEP00000017684.2};
OS Anabas testudineus (Climbing perch) (Anthias testudineus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Anabantaria; Anabantiformes; Anabantoidei; Anabantidae; Anabas.
OX NCBI_TaxID=64144 {ECO:0000313|Ensembl:ENSATEP00000017684.2, ECO:0000313|Proteomes:UP000265040};
RN [1] {ECO:0000313|Ensembl:ENSATEP00000017684.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3Q1IDU2; -.
DR STRING; 64144.ENSATEP00000017684; -.
DR Ensembl; ENSATET00000017980.2; ENSATEP00000017684.2; ENSATEG00000012294.2.
DR GeneTree; ENSGT00940000159599; -.
DR OrthoDB; 5406576at2759; -.
DR Proteomes; UP000265040; Unplaced.
DR CDD; cd01260; PH_CNK_mammalian-like; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR017874; CRIC_domain.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR PANTHER; PTHR12844; CONNECTOR ENCHANCER OF KINASE SUPPRESSOR OF RAS; 1.
DR PANTHER; PTHR12844:SF10; CONNECTOR ENHANCER OF KINASE SUPPRESSOR OF RAS 1; 1.
DR Pfam; PF10534; CRIC_ras_sig; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF00536; SAM_1; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00454; SAM; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR PROSITE; PS51290; CRIC; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50105; SAM_DOMAIN; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000265040}.
FT DOMAIN 7..70
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 78..171
FT /note="CRIC"
FT /evidence="ECO:0000259|PROSITE:PS51290"
FT DOMAIN 340..440
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 265..288
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 447..510
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 552..610
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 269..288
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 447..482
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 685 AA; 76777 MW; 30C5CC2BF6E14F74 CRC64;
MEPITSWSEG RVSEWLQGLD APLHQYPVSE WHLSGLDLLQ LTSQDLEKLG VQKIGHQELI
LEAVEKLCSL TYGIGGESLR GLTEKLRAVA HTLQMGIQSR WRLNSYDGRS TTKLPVGVLQ
VVVELITSAK GLFSLLNRYQ FHQLSGYTSS KHIFNYCRDL GEIVHKDTNV HEKEKDIISI
CRQLVEVCDE ILNCGSEALL AHTAQLESVD LVPVSPGDQL GIEITSSGSS NHYVTGTAAE
VGWSRANLVK KLRENPSGVT LVLKRTPGSV QHRDSKEEAE EDKYEEENPR HSILERVAAS
KEKKTGIIIA WQMMIPGCNL LTGMSTALSR RRVSCRELGS PDCDGWLWKK RKESSVFITQ
KWQRFWFILK GPSLYWYTTQ QAEKAEGLVN IASYTIESAG EHKRKNVFKM FHQRFQNFFF
AAENVTDMSK WINCLITAIQ KHKKLHKGPA SEEECYSETE SEGERSPSPR RTNKDKKVQS
NTLPRPKGKM TKGPSPILPT GGSKGTAGPV DEMSMMLNNI KEGGVSLTGH EQPLTHDQFR
KSFIRRNKNP VINEKAHALR ALQSTLKAKE AELQQINKVL EESDLTASKY RQWKEQNEEL
LADIEKLYAL KTSKAGDKAA VQGTSTEEVA LETAAMETAN TETEGAYRLS LSDGEQLVDA
ELSDVFVDLS EMAESGTSVD NYFYI
//
