ID A0A3Q1IR32_ANATE Unreviewed; 291 AA.
AC A0A3Q1IR32;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyldiphosphate specific] {ECO:0000256|ARBA:ARBA00012596};
DE EC=2.5.1.87 {ECO:0000256|ARBA:ARBA00012596};
OS Anabas testudineus (Climbing perch) (Anthias testudineus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Anabantaria; Anabantiformes; Anabantoidei; Anabantidae; Anabas.
OX NCBI_TaxID=64144 {ECO:0000313|Ensembl:ENSATEP00000020138.1, ECO:0000313|Proteomes:UP000265040};
RN [1] {ECO:0000313|Ensembl:ENSATEP00000020138.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=(2E,6E)-farnesyl diphosphate + n isopentenyl diphosphate = di-
CC trans,poly-cis-polyprenyl diphosphate + n diphosphate;
CC Xref=Rhea:RHEA:53008, Rhea:RHEA-COMP:13431, ChEBI:CHEBI:33019,
CC ChEBI:CHEBI:128769, ChEBI:CHEBI:136960, ChEBI:CHEBI:175763;
CC EC=2.5.1.87; Evidence={ECO:0000256|ARBA:ARBA00000976};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- PATHWAY: Protein modification; protein glycosylation.
CC {ECO:0000256|ARBA:ARBA00004922}.
CC -!- SIMILARITY: Belongs to the UPP synthase family.
CC {ECO:0000256|ARBA:ARBA00005432}.
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DR AlphaFoldDB; A0A3Q1IR32; -.
DR STRING; 64144.ENSATEP00000020138; -.
DR Ensembl; ENSATET00000020484.2; ENSATEP00000020138.1; ENSATEG00000014012.2.
DR GeneTree; ENSGT00390000003223; -.
DR InParanoid; A0A3Q1IR32; -.
DR OrthoDB; 444436at2759; -.
DR UniPathway; UPA00378; -.
DR Proteomes; UP000265040; Unplaced.
DR GO; GO:1904423; C:dehydrodolichyl diphosphate synthase complex; IEA:InterPro.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0045547; F:dehydrodolichyl diphosphate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0019408; P:dolichol biosynthetic process; IEA:InterPro.
DR GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.40.1180.10; Decaprenyl diphosphate synthase-like; 1.
DR InterPro; IPR038887; Nus1/NgBR.
DR InterPro; IPR001441; UPP_synth-like.
DR InterPro; IPR036424; UPP_synth-like_sf.
DR PANTHER; PTHR21528:SF0; DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT NUS1; 1.
DR PANTHER; PTHR21528; UNCHARACTERIZED; 1.
DR Pfam; PF01255; Prenyltransf; 1.
DR SUPFAM; SSF64005; Undecaprenyl diphosphate synthase; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000265040};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
SQ SEQUENCE 291 AA; 32903 MW; 531A3232F7AFA42F CRC64;
MALLYGLLWR LLLVLVHVNR ALVSWLRVRL RSWKGRLWER AMAALLLPVA LAGFSDRQKK
SNHNPDAKAN TLTGNLTASR RTRWLCDGRS LEKLPVHIGL LVAEDEPSYT DIANLVVWCM
AVGISYVSVY DNQGFFRKNN SRLLEEIVRQ QQDLLGAEAS KYNVEFLSNG SDKHQHQVLS
CTPTVKVLSP EDGKQSIVQA AQQLCRSVEN KERSSKDISV SMLDILLREA KNIPDPELVV
KFGPVDSTLG FLPWHIRLTE FIFLPSHKNV SYEDLLGALQ RYGACQQRLG Q
//
