ID   A0A3Q1IUL7_ANATE        Unreviewed;       164 AA.
AC   A0A3Q1IUL7;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=Caveolin {ECO:0000256|RuleBase:RU000680};
OS   Anabas testudineus (Climbing perch) (Anthias testudineus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Anabantaria; Anabantiformes; Anabantoidei; Anabantidae; Anabas.
OX   NCBI_TaxID=64144 {ECO:0000313|Ensembl:ENSATEP00000007416.1, ECO:0000313|Proteomes:UP000265040};
RN   [1] {ECO:0000313|Ensembl:ENSATEP00000007416.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- FUNCTION: May act as a scaffolding protein within caveolar membranes.
CC       Interacts directly with G-protein alpha subunits and can functionally
CC       regulate their activity. {ECO:0000256|RuleBase:RU000680}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004202,
CC       ECO:0000256|RuleBase:RU000680}; Peripheral membrane protein
CC       {ECO:0000256|ARBA:ARBA00004202, ECO:0000256|RuleBase:RU000680}. Golgi
CC       apparatus membrane {ECO:0000256|RuleBase:RU000680}; Peripheral membrane
CC       protein {ECO:0000256|RuleBase:RU000680}. Membrane, caveola
CC       {ECO:0000256|RuleBase:RU000680}; Peripheral membrane protein
CC       {ECO:0000256|RuleBase:RU000680}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein
CC       {ECO:0000256|ARBA:ARBA00004170}.
CC   -!- SIMILARITY: Belongs to the caveolin family.
CC       {ECO:0000256|ARBA:ARBA00010988, ECO:0000256|RuleBase:RU000680}.
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DR   AlphaFoldDB; A0A3Q1IUL7; -.
DR   STRING; 64144.ENSATEP00000007416; -.
DR   Ensembl; ENSATET00000007540.2; ENSATEP00000007416.1; ENSATEG00000005189.2.
DR   GeneTree; ENSGT00950000183006; -.
DR   InParanoid; A0A3Q1IUL7; -.
DR   OMA; IQTVWAS; -.
DR   Proteomes; UP000265040; Unplaced.
DR   GO; GO:0005901; C:caveola; IEA:UniProtKB-SubCell.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0070836; P:caveola assembly; IEA:InterPro.
DR   InterPro; IPR001612; Caveolin.
DR   InterPro; IPR018361; Caveolin_CS.
DR   PANTHER; PTHR10844; CAVEOLIN; 1.
DR   PANTHER; PTHR10844:SF29; CAVEOLIN; 1.
DR   Pfam; PF01146; Caveolin; 1.
DR   PROSITE; PS01210; CAVEOLIN; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|RuleBase:RU000680};
KW   Golgi apparatus {ECO:0000256|ARBA:ARBA00023034,
KW   ECO:0000256|RuleBase:RU000680};
KW   Membrane {ECO:0000256|RuleBase:RU000680, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265040};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        79..105
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        125..148
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   164 AA;  18696 MW;  4A87EB3B86C548E8 CRC64;
     GKLMEVKMDV ESADLDSTHH NTGRLTQDRD PKGVNKSLKV TFEDVIAEPP SVRSFDNVWV
     WSHGLFEVSR LWCYRFISLL LAVPVSLAAG ILLAVLSCLH IWLIMPCVQL LHINMRWVQT
     VWSSMLNILI TPFFTSTGRC CSSVIIYVEK DKDEFRELSG SREI
//