ID   A0A3Q1IWX2_ANATE        Unreviewed;       483 AA.
AC   A0A3Q1IWX2;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   02-JUN-2021, sequence version 2.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=Occludin {ECO:0000256|ARBA:ARBA00016772};
OS   Anabas testudineus (Climbing perch) (Anthias testudineus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Anabantaria; Anabantiformes; Anabantoidei; Anabantidae; Anabas.
OX   NCBI_TaxID=64144 {ECO:0000313|Ensembl:ENSATEP00000026682.2, ECO:0000313|Proteomes:UP000265040};
RN   [1] {ECO:0000313|Ensembl:ENSATEP00000026682.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell junction, tight junction
CC       {ECO:0000256|ARBA:ARBA00004435}. Cell membrane
CC       {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the ELL/occludin family.
CC       {ECO:0000256|ARBA:ARBA00009171, ECO:0000256|PROSITE-ProRule:PRU01324}.
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DR   AlphaFoldDB; A0A3Q1IWX2; -.
DR   Ensembl; ENSATET00000027106.2; ENSATEP00000026682.2; ENSATEG00000018404.2.
DR   GeneTree; ENSGT00940000167296; -.
DR   Proteomes; UP000265040; Unplaced.
DR   GO; GO:0005923; C:bicellular tight junction; IEA:UniProtKB-SubCell.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0070830; P:bicellular tight junction assembly; IEA:InterPro.
DR   Gene3D; 6.10.140.340; -; 1.
DR   InterPro; IPR031176; ELL/occludin.
DR   InterPro; IPR008253; Marvel.
DR   InterPro; IPR002958; Occludin.
DR   InterPro; IPR010844; Occludin_ELL.
DR   PANTHER; PTHR23288:SF38; OCCLUDIN; 1.
DR   PANTHER; PTHR23288; OCCLUDIN AND RNA POLYMERASE II ELONGATION FACTOR ELL; 1.
DR   Pfam; PF01284; MARVEL; 1.
DR   Pfam; PF07303; Occludin_ELL; 1.
DR   PRINTS; PR01258; OCCLUDIN.
DR   SUPFAM; SSF144292; occludin/ELL-like; 1.
DR   PROSITE; PS51225; MARVEL; 1.
DR   PROSITE; PS51980; OCEL; 1.
PE   3: Inferred from homology;
KW   Cell junction {ECO:0000256|ARBA:ARBA00022949};
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW   ProRule:PRU00581}; Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265040};
KW   Tight junction {ECO:0000256|ARBA:ARBA00022427};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW   ProRule:PRU00581};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        48..69
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        76..93
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        113..132
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        144..171
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        229..250
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          40..254
FT                   /note="MARVEL"
FT                   /evidence="ECO:0000259|PROSITE:PS51225"
FT   DOMAIN          383..483
FT                   /note="OCEL"
FT                   /evidence="ECO:0000259|PROSITE:PS51980"
FT   REGION          331..360
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        336..358
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   483 AA;  54939 MW;  A52944229D05E77A CRC64;
     WLLRPHQDVT IANMSPTPTT SLQDSYYMEE RPQHFYRWFS PPGFVKTFQG ATVLICFLIF
     SCVASTLVWD MNGFGYGGYG SIGGVAGTGS GYYGGSYGYG NSYMTPHSAK SAMISMAAIN
     FLVSLGFLTG SFSRSRMTRG CRFYLIVFIC DIILAVLQVS GIIDIIFVIG VNPMSQSSQS
     MLYNPMLMMC QNIQGSPSLS GSVGAGFPGG FLMYNQYLQH YCYMDPEEAV ALVLGLMVVL
     ALSLSAYYAY KTRSKIWRHG KANIYWDEPV ARPSDGQDVQ DWVSKVKFIS SSGTLGMIVC
     QQSLTVKDRS KTVKPLYQDS RVVVCSSSSS DETESIWKPP DYHVEREKRK DREPRSAAQK
     TVEYQYETGY TTEDTGNELD HKDYLYRLYP EITSDEQRQQ YKKEFDSDLA RYKSLCAEMD
     GISDQMHNLS RELDTLDEGS MKYEVQKNKR EPDYQAKKKR CKELRQKLFH IKRLVKLYDR
     HLC
//