ID A0A3Q1IZ46_ANATE Unreviewed; 808 AA.
AC A0A3Q1IZ46;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Spectrin repeat containing, nuclear envelope 2b {ECO:0000313|Ensembl:ENSATEP00000024389.2};
OS Anabas testudineus (Climbing perch) (Anthias testudineus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Anabantaria; Anabantiformes; Anabantoidei; Anabantidae; Anabas.
OX NCBI_TaxID=64144 {ECO:0000313|Ensembl:ENSATEP00000024389.2, ECO:0000313|Proteomes:UP000265040};
RN [1] {ECO:0000313|Ensembl:ENSATEP00000024389.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the nesprin family.
CC {ECO:0000256|ARBA:ARBA00008619}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A3Q1IZ46; -.
DR STRING; 64144.ENSATEP00000024389; -.
DR Ensembl; ENSATET00000024780.2; ENSATEP00000024389.2; ENSATEG00000016899.2.
DR GeneTree; ENSGT00940000154656; -.
DR InParanoid; A0A3Q1IZ46; -.
DR Proteomes; UP000265040; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0005635; C:nuclear envelope; IEA:UniProt.
DR CDD; cd00176; SPEC; 3.
DR Gene3D; 1.20.58.60; -; 4.
DR InterPro; IPR026696; AKAP6/CEP68.
DR InterPro; IPR012315; KASH.
DR InterPro; IPR018159; Spectrin/alpha-actinin.
DR InterPro; IPR002017; Spectrin_repeat.
DR PANTHER; PTHR14514:SF4; NESPRIN-2; 1.
DR PANTHER; PTHR14514; PKA ANCHORING PROTEIN; 1.
DR Pfam; PF10541; KASH; 1.
DR Pfam; PF00435; Spectrin; 2.
DR SMART; SM01249; KASH; 1.
DR SMART; SM00150; SPEC; 5.
DR SUPFAM; SSF46966; Spectrin repeat; 4.
DR PROSITE; PS51049; KASH; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU00385}; Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000265040};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU00385};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TOPO_DOM 1..757
FT /note="Cytoplasmic"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00385"
FT TRANSMEM 758..778
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TOPO_DOM 779..808
FT /note="Perinuclear space"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00385"
FT DOMAIN 749..808
FT /note="KASH"
FT /evidence="ECO:0000259|PROSITE:PS51049"
SQ SEQUENCE 808 AA; 92785 MW; 2619DA077A075F71 CRC64;
MVIVFDLVRK LKETLVTVQQ LDKNMSNLRT WLSRIEAELA KPVVYNVCHS DEIQKKLAEQ
QDLQRDIEQH TESVASVLTL CDVLLHDADA CGSDTENDSI QQTTRSLDRR WRNICAMSME
RRMRIEETWR LWCKFLDDYS RFDDWLKTAE LTAANPDSSS VLYTSAKEEL KKFEAFQRQV
HERLTQLELV NKQYRRLARE NRTDAASKLK VMVHEGNQRW DSLQRRVAAV LRRLKHFTSQ
REDFEGTREG ILVWLTEMDL QLTNVEHFSE SDIEDKMRQL NGFQQEITLN TNKIDALIVF
GENLIQKSAP LDAVLIEDEL EELHSYCQEV FGRVARFHHR LVNRRPVSSL KCWSQTEAAF
SLDPVLSTFH SVSLSSVMCH LLAPPLERSG RETPVSVDSI PLEWDHTVDV GGSSSHEDDE
DATFFSALSG NDSCLLFSAK LMSECSGSID SVKRVKLILN DEEELVDVGL TTHVNLLTSS
GVIERWELLQ AQKLDSDTGI KQDLEQWQKL NSDLCDVTSW LGRVLPELER LQRIAPSTSI
RDIEVNIRKL KDMQKTFNSY KCLMISVNLS SRHFLRGDSA ELRELQEALG SANHSWTQAC
SGLESWERRL HSALMQCQEF HQMLHSLLMW LAQAENKLCS VNTLYETLFP RHSLPQTLQE
ELHSRQRQVS SLQEISSQLL LEATGEDSIE AKEKVHVIGN KLCLLLRQVA ADLHTLQRTV
GQQQHLTPNV GFLFDVELSC TTRDSSPHRP FFYRVLRAAF PLHLLFVVLL VLACLVPLSE
EDYSCTLSNN FARSFYPMLR YTNGPPPT
//
