ID   A0A3Q1J0L9_ANATE        Unreviewed;       879 AA.
AC   A0A3Q1J0L9;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   02-JUN-2021, sequence version 2.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Epidermal growth factor receptor substrate 15-like 1 {ECO:0000313|Ensembl:ENSATEP00000009206.2};
OS   Anabas testudineus (Climbing perch) (Anthias testudineus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Anabantaria; Anabantiformes; Anabantoidei; Anabantidae; Anabas.
OX   NCBI_TaxID=64144 {ECO:0000313|Ensembl:ENSATEP00000009206.2, ECO:0000313|Proteomes:UP000265040};
RN   [1] {ECO:0000313|Ensembl:ENSATEP00000009206.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A3Q1J0L9; -.
DR   STRING; 64144.ENSATEP00000009206; -.
DR   Ensembl; ENSATET00000009366.2; ENSATEP00000009206.2; ENSATEG00000006383.2.
DR   GeneTree; ENSGT00940000155438; -.
DR   Proteomes; UP000265040; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   CDD; cd00052; EH; 3.
DR   Gene3D; 1.10.287.1490; -; 1.
DR   Gene3D; 1.10.238.10; EF-hand; 3.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR   InterPro; IPR002048; EF_hand_dom.
DR   InterPro; IPR000261; EH_dom.
DR   InterPro; IPR003903; UIM_dom.
DR   PANTHER; PTHR11216; EH DOMAIN; 1.
DR   PANTHER; PTHR11216:SF161; EPIDERMAL GROWTH FACTOR RECEPTOR PATHWAY SUBSTRATE CLONE 15, ISOFORM A; 1.
DR   Pfam; PF12763; EF-hand_4; 3.
DR   SMART; SM00054; EFh; 4.
DR   SMART; SM00027; EH; 3.
DR   SMART; SM00726; UIM; 2.
DR   SUPFAM; SSF47473; EF-hand; 3.
DR   SUPFAM; SSF57997; Tropomyosin; 1.
DR   PROSITE; PS00018; EF_HAND_1; 1.
DR   PROSITE; PS50222; EF_HAND_2; 2.
DR   PROSITE; PS50031; EH; 3.
DR   PROSITE; PS50330; UIM; 1.
PE   4: Predicted;
KW   Calcium {ECO:0000256|ARBA:ARBA00022837};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265040}.
FT   DOMAIN          40..102
FT                   /note="EH"
FT                   /evidence="ECO:0000259|PROSITE:PS50031"
FT   DOMAIN          114..202
FT                   /note="EH"
FT                   /evidence="ECO:0000259|PROSITE:PS50031"
FT   DOMAIN          146..181
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000259|PROSITE:PS50222"
FT   DOMAIN          264..299
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000259|PROSITE:PS50222"
FT   DOMAIN          265..355
FT                   /note="EH"
FT                   /evidence="ECO:0000259|PROSITE:PS50031"
FT   REGION          207..251
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          337..370
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          558..659
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          699..831
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          376..543
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          844..871
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        227..251
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        558..575
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        699..715
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        720..736
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        761..776
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        815..831
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   879 AA;  96314 MW;  6E756CC55F10D5C2 CRC64;
     MSHVGKFSQP LLSTYCDLCG CSKVDPGSTG RVGPTEAALF LKKSGLPDIT LGKIWDLADP
     DGKGYLDKQG FYVALRLVAC AQSGQEVSLS SLNLTVPPPK FVSLTSLQQL GNLEKSKFDG
     IFESLAPVNG LLSGEKVKPV LINSKLPLDV LGKVWDLSDI DKDGHLDKDE FAVAMHLVYR
     ALEKEPVPAL LPSSLVPPSK RKKSLCSVAS SVPGLPASPP PPKDSLRSTP SHGSMNSLNS
     TGSLSPKHTL KSGQHSVNWL VPVSERGRYD DIFLKTDADL DGFVSGQEVK EIFMQSGLSQ
     NVLAHIWALA DTRQIGKLTR EQFALAMHLI QQKVSKGIDP PQSLTPEMIP PSERGTPVPD
     SSSSMGSGEF TGIKELDDIS QEIAQLQREK YTLEQDIRET EEAIRHKSAE VQVMQNDLDR
     EAASLQELEA QKQDAQDRLE EMDQQKNKLE DMLNEVRMKC QEESQMISTL QSQIHSQESD
     LQSQEEELSR AKADLGRLQQ EETQLEQSLA AGKIQLETII KSLKATQDEI NQARSKLSQI
     QDSQQEVSKS IEQYNSTLNG THGGSMTNLA DMSESYSDRE NGGFPAMEDP FKVNPSVFIN
     QPQELHTDPF HSEDPFKTDP FKGDPFQNDP FAKQPPASTD PFGGDPFKET DPFKASSEDF
     FKKTTKMDPF STPDPFSKSA TLPSKVLVKD LFGTLDPFGG SSFSSSSNSS AGFADFSHMS
     KPRDPFEGRA MFVDDPFNRK NDTPALPPKK TVPQRPKPPS GKSTPVSMSG TGDTSKPCDP
     FQPFGGGEAI DPFQSKKGLG DPFCGKDPFA PSSASSKAPK DSTSGFADFS SFGNEAQQLE
     WAKRESERAE RERLKRLRQQ EQEDLELAIA LSKAEMSNA
//