ID A0A3Q1J0M4_ANATE Unreviewed; 888 AA.
AC A0A3Q1J0M4;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=G-protein coupled receptors family 3 profile domain-containing protein {ECO:0000259|PROSITE:PS50259};
OS Anabas testudineus (Climbing perch) (Anthias testudineus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Anabantaria; Anabantiformes; Anabantoidei; Anabantidae; Anabas.
OX NCBI_TaxID=64144 {ECO:0000313|Ensembl:ENSATEP00000009211.2, ECO:0000313|Proteomes:UP000265040};
RN [1] {ECO:0000313|Ensembl:ENSATEP00000009211.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 3 family.
CC {ECO:0000256|ARBA:ARBA00007242}.
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DR AlphaFoldDB; A0A3Q1J0M4; -.
DR STRING; 64144.ENSATEP00000009211; -.
DR Ensembl; ENSATET00000009371.2; ENSATEP00000009211.2; ENSATEG00000006449.2.
DR GeneTree; ENSGT01030000234648; -.
DR Proteomes; UP000265040; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR CDD; cd15451; 7tmC_mGluR7; 1.
DR CDD; cd06376; PBP1_mGluR_groupIII; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 2.10.50.30; GPCR, family 3, nine cysteines domain; 1.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR000337; GPCR_3.
DR InterPro; IPR011500; GPCR_3_9-Cys_dom.
DR InterPro; IPR038550; GPCR_3_9-Cys_sf.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR017979; GPCR_3_CS.
DR InterPro; IPR001786; GPCR_3_mGluR4.
DR InterPro; IPR000162; GPCR_3_mtglu_rcpt.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR24060; METABOTROPIC GLUTAMATE RECEPTOR; 1.
DR PANTHER; PTHR24060:SF98; METABOTROPIC GLUTAMATE RECEPTOR 7; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF07562; NCD3G; 1.
DR PRINTS; PR00248; GPCRMGR.
DR PRINTS; PR01054; MTABOTROPC4R.
DR PRINTS; PR00593; MTABOTROPICR.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00979; G_PROTEIN_RECEP_F3_1; 1.
DR PROSITE; PS00980; G_PROTEIN_RECEP_F3_2; 1.
DR PROSITE; PS00981; G_PROTEIN_RECEP_F3_3; 1.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000265040};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..888
FT /note="G-protein coupled receptors family 3 profile domain-
FT containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5030080161"
FT TRANSMEM 575..601
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 613..633
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 645..666
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 739..760
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 772..794
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 814..836
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 575..849
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
FT REGION 856..888
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 888 AA; 99117 MW; 81798F7AD05D5EAC CRC64;
MGLGSVWRVF WLVRTVVDFA LAQETYAPHS IRTEGHLTLG GLFPVHARGA DGTPCGDLKK
ENGIQRLEAM MYALDQINQD EQLLPNITLG ARVLDTCSRD TYALEQSLTF VQALITKDTS
DVRCTNGEPP VFVKPEKVVG VIGASASSVS IMVANILRLF QIPQISYAST APELSDDRRY
DFFSRVVPPD SFQAQAMVDI IRALGWTYVS TIASEGSYGE KGVEAFTQLS KEAGGICIAQ
SLKIPHNPKV EDYDKVIQQL LETQHSRAVI IFASEEDIRG VLGATKRANQ VGHFLWIGSD
SWGAKSSPIQ QLEDVAEGAV TVLPKRSSIK GFDEYFTALT LENNRRNVWF AEFWEENFDC
RLLSASKKED TSRKCTGQER IGIDSKYEQE GKVQFVIDAV YAMAHALHNM QRDLCPDHPG
VCPQMESAEG KTLLKYIRNT SFNGSAGTSV VFNKNGDAPG RYDLFQFQMT NSSTAEYKVV
GQWVESLQLR LEDLQWPDGE QEVPISVCSL PCKTGERKKK VKGMPCCWHC ELCDGYQYQY
DETSCRLCAY NMRPNSNRTA CQPIPIVKLE WHSPWAIIPV FLAMLGIIAT IFVMATFIRY
NDTPIVRASG RELSYVLLTG IFLCYIITFL MIAKPDVAVC AFRRIFLGLG MCISYAALLT
KTNRIYRIFE QGKQTVTAPR FISPTSQIAI TSSLICVQLL GVLVWFAVDP PNTIVDYDEQ
KTINPMLARG VLKCDITDLQ IICSLGYSIL LMVTCTIYAI KTRDVPEDFN EAKPIGFTMY
TTCIVWLAFI PIFFGTAQSA EKLYIQTTTL TISMNLSASV ALGMLYMPKV YIIIFHPELN
VQKRKRSFKA VVTAATMSSR LSQKPNERPN GEAKTELCEN PAADPMSK
//
