ID A0A3Q1J3Y1_ANATE Unreviewed; 833 AA.
AC A0A3Q1J3Y1;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Low density lipoprotein receptor-related protein 3 {ECO:0000313|Ensembl:ENSATEP00000010031.1};
OS Anabas testudineus (Climbing perch) (Anthias testudineus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Anabantaria; Anabantiformes; Anabantoidei; Anabantidae; Anabas.
OX NCBI_TaxID=64144 {ECO:0000313|Ensembl:ENSATEP00000010031.1, ECO:0000313|Proteomes:UP000265040};
RN [1] {ECO:0000313|Ensembl:ENSATEP00000010031.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane, coated pit
CC {ECO:0000256|ARBA:ARBA00037878}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00124}.
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DR AlphaFoldDB; A0A3Q1J3Y1; -.
DR STRING; 64144.ENSATEP00000010031; -.
DR Ensembl; ENSATET00000010207.2; ENSATEP00000010031.1; ENSATEG00000007069.2.
DR GeneTree; ENSGT00940000160021; -.
DR InParanoid; A0A3Q1J3Y1; -.
DR OMA; NFDLMES; -.
DR OrthoDB; 2916406at2759; -.
DR Proteomes; UP000265040; Unplaced.
DR GO; GO:0005905; C:clathrin-coated pit; IEA:UniProtKB-KW.
DR CDD; cd00041; CUB; 2.
DR CDD; cd00112; LDLa; 5.
DR Gene3D; 4.10.1220.10; EGF-type module; 1.
DR Gene3D; 4.10.400.10; Low-density Lipoprotein Receptor; 4.
DR Gene3D; 2.60.120.290; Spermadhesin, CUB domain; 2.
DR InterPro; IPR000859; CUB_dom.
DR InterPro; IPR036055; LDL_receptor-like_sf.
DR InterPro; IPR023415; LDLR_class-A_CS.
DR InterPro; IPR002172; LDrepeatLR_classA_rpt.
DR InterPro; IPR035914; Sperma_CUB_dom_sf.
DR PANTHER; PTHR24270; LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED; 1.
DR PANTHER; PTHR24270:SF22; LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 3; 1.
DR Pfam; PF00431; CUB; 1.
DR Pfam; PF00057; Ldl_recept_a; 4.
DR PRINTS; PR00261; LDLRECEPTOR.
DR SMART; SM00042; CUB; 2.
DR SMART; SM00192; LDLa; 5.
DR SUPFAM; SSF57424; LDL receptor-like module; 5.
DR SUPFAM; SSF49854; Spermadhesin, CUB domain; 2.
DR PROSITE; PS01180; CUB; 2.
DR PROSITE; PS01209; LDLRA_1; 3.
DR PROSITE; PS50068; LDLRA_2; 5.
PE 4: Predicted;
KW Coated pit {ECO:0000256|ARBA:ARBA00023176};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00124}; Membrane {ECO:0000256|ARBA:ARBA00023176};
KW Reference proteome {ECO:0000313|Proteomes:UP000265040};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..833
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018648913"
FT DOMAIN 23..136
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 231..343
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT REGION 637..715
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 736..807
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 644..669
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 686..706
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 753..784
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 785..807
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 143..155
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 150..168
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 162..177
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 211..226
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 366..381
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 405..420
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 423..435
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 430..448
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 442..457
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
SQ SEQUENCE 833 AA; 91053 MW; 0C13E452BB4D76C5 CRC64;
MGLTVPVLGL LWFRSALLCA AGCSERVEVH TERRGVIYSP SWPLNYPAGV NCSWHIQGGQ
GEVITISFRN FDLAESGHCL GDWLLLTPSW NGESRLCGSM LPPPFISTRG RVWLYFHSQA
NSSGQAQGFR LSYIRGHLGQ SSCQSDEFLC GNGKCLPRSW KCNGQDECGD TTDERGCSPP
PTETQPGLCP FGSLPCTEAQ STRCLPAALR CNGARDCSDG TDELGCPDTT CGKRLGNFYG
SFASPDFFRA NRSAAAELRC SWLLDTQDPK PIVLQLDLQL GPRDSLHVYD GLLQRAEHLL
QVLSYHNNRR PALLESSRGQ MSVLYMAQPH SPGHGFNATY QVKGYCFPGE RPCGSDQGCY
SERQRCDGYW HCPSGRDEEA CPTCPDGEFP CEGGTGVCYP ASERCNNQKR CPDGSDEKNC
YDCQPGNFHC GTNLCIFETW RCDGQEDCLD GSDERDCLAA VPRKVITAAL IGSLVCSLLL
VIALGCALKL HSLRSREYRA FETQMTRMEA EFVQREAPPS YGQLIAQGLI PPVEDFPVYN
ATQASVLQNL RMAMHRQIRR HSSRRSTSSS SRRHLGHLWS RLFNSGGRAR GHAPLLDPPG
PSQVTLGLHS YRTVTEQGPL GRTRGWRGDE VGVAGRPGSY CSATMDPETC TPESPASPLS
SQSADSPEEE QLSPDSRGGS RGPQAEPPSP VQSDSSTNSG LPPTPQEASV PLSHPRASRK
LVLELAVNLK GVSLRRYSPL GPLSPISPPV FPSNSQIPTT QRHPLCSEVT SPAESLSSSV
KAEDSDSHIA VEVPSRERRS RDERRREAKI RLCRLSRALS DEGVDSGRET TPC
//
