ID A0A3Q1J957_ANATE Unreviewed; 1269 AA.
AC A0A3Q1J957;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Si:ch73-335l21.1 {ECO:0000313|Ensembl:ENSATEP00000029410.1};
OS Anabas testudineus (Climbing perch) (Anthias testudineus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Anabantaria; Anabantiformes; Anabantoidei; Anabantidae; Anabas.
OX NCBI_TaxID=64144 {ECO:0000313|Ensembl:ENSATEP00000029410.1, ECO:0000313|Proteomes:UP000265040};
RN [1] {ECO:0000313|Ensembl:ENSATEP00000029410.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3Q1J957; -.
DR STRING; 64144.ENSATEP00000029410; -.
DR Ensembl; ENSATET00000029857.2; ENSATEP00000029410.1; ENSATEG00000020267.2.
DR GeneTree; ENSGT00940000166370; -.
DR InParanoid; A0A3Q1J957; -.
DR OMA; PEAEMGH; -.
DR Proteomes; UP000265040; Unplaced.
DR GO; GO:0005158; F:insulin receptor binding; IEA:InterPro.
DR GO; GO:0008286; P:insulin receptor signaling pathway; IEA:InterPro.
DR CDD; cd01257; PH_IRS; 1.
DR CDD; cd01204; PTB_IRS; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR InterPro; IPR039011; IRS.
DR InterPro; IPR002404; IRS_PTB.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR10614; INSULIN RECEPTOR SUBSTRATE; 1.
DR PANTHER; PTHR10614:SF8; INSULIN RECEPTOR SUBSTRATE 3; 1.
DR Pfam; PF02174; IRS; 1.
DR Pfam; PF00169; PH; 1.
DR PRINTS; PR00628; INSULINRSI.
DR SMART; SM01244; IRS; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00310; PTBI; 1.
DR SUPFAM; SSF50729; PH domain-like; 2.
DR PROSITE; PS51064; IRS_PTB; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000265040}.
FT DOMAIN 13..115
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 138..242
FT /note="IRS-type PTB"
FT /evidence="ECO:0000259|PROSITE:PS51064"
FT REGION 240..594
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 645..881
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 913..948
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1020..1075
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1102..1132
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1157..1181
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 244..268
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 295..315
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 332..410
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 418..466
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 480..506
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 514..530
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 562..587
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 658..674
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 680..694
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 711..726
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 737..751
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 782..876
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 934..948
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1027..1074
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1117..1132
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1269 AA; 132845 MW; FF7B97E5DCC68D5F CRC64;
MEGQAGEQHS YEDVRKSGYL RKQKSMHRRY FVLRAASERG PARLEYYESE KKFRGKAPVP
KKAVALETCF NINKRADSKN KHMIVLYTRA ESFAIAAEND ADQEEWYQAM VDLQCKSKNP
TDSGAAGDYG VPNPGPAFKE VWQVKVWPKG LGQAKNLVGI YRLCLTDKTV NFVKLNSDAA
AVVLQLMNVR RCGHSENFFF VEVGRSAVTG PGEFWMQVDD SVVAQNMHET LLEAMKALSE
EFRQRSKSQS NSGPGGGATA SNPISVPSRR HHPNPPPSQV GFTRRPRTEP PGGSNGGAGG
TSASASPTPR HSFPRSRTAS DGAKGEDGTT GTPLLQGPSS SPSTNGSCST TPILSSKSVR
SGSTTAGKTP LGLMRSISTP TPSTAPSLSS SSGHGSEFGG VTSSVSAGPG SGAYSHVASH
RASVSGSPSD YGSSDEYGSS PGDHTLLPSP SLPGSSVDSV GSQSLGEEGA NYILMGQRGS
GGGGSSNQGS FISSCLPASG TAVCGSQPPS RRVLRRSSSR ECEAERRLLS KRASLPPMAL
ERLAPRQRRA EEPADEDSAD YAIMSRSTSR ESFTSTSSST QRESVTGVGS VGGGGGYLDV
SGEFKSEGGG GASSSVDVGM DNGYMSMLPG VTQPPVSLSQ SLAVSVPDSD SKPADDYMAM
TPNSSVSPPQ QIRPPTSDGY MIMSPNSSCS PDQRGGLSGG AWVGSGSADS RAGSDYMNMS
PISARSVNGS PPPPEHSGHL ETSSHQQVPK MVYSYYSLPR SYKHNPSAGH FDDGPGRGRR
PNGSSNRGNS RTAGNHQEQP AAGNSVGGCH LSLSSSSYSS SSASSESLGE NEDRATQAGS
TMTGGTPNSK DGSKLQQKRG SGGLSKQGSH TRSRPVSLFV DVSKANTLPR VRENPLPPEP
KSPGEYVSIE FKGEEYSQPG VGRGRGRGLR HGLSLPHSSS TYHPQHRPTS CLGNFIPISR
SPSAPITPPA ASEYVNMDLG PSLSPSPLSL TPLVFPSFHT PPTPPTLAHA PKKAVEVADA
PVRKSRESVP SVTQSESPTS CGDYTEMAFS LNNNTAPRPS SNVSPQTPSP TRTVPVLSRG
LDFPLAKPGL NLDHGAKVIR ADPQGRRRHC SETFLAPPSL PASTSTSSSS TASLFPEHAQ
AVARRLGFES MLWGNGAVTD TPTQFPLPGQ QQSNPTSSTE QGLNYIDLDL ANKESPHLSL
DGQSGSQTSS RLFSVLGGGS GVGGVGVGAA VGSSSSSSSS LNTYASIDFY KSEELRTHQN
GNKEGTGTF
//
