ID A0A3Q1JIY8_ANATE Unreviewed; 311 AA.
AC A0A3Q1JIY8;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=F5/8 type C domain-containing protein {ECO:0000259|PROSITE:PS50022};
OS Anabas testudineus (Climbing perch) (Anthias testudineus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Anabantaria; Anabantiformes; Anabantoidei; Anabantidae; Anabas.
OX NCBI_TaxID=64144 {ECO:0000313|Ensembl:ENSATEP00000035107.2, ECO:0000313|Proteomes:UP000265040};
RN [1] {ECO:0000313|Ensembl:ENSATEP00000035107.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Acts as a defensive agent. Recognizes blood group fucosylated
CC oligosaccharides including A, B, H and Lewis B-type antigens. Does not
CC recognize Lewis A antigen and has low affinity for monovalent haptens.
CC {ECO:0000256|ARBA:ARBA00002219}.
CC -!- SUBUNIT: Homotrimer. {ECO:0000256|ARBA:ARBA00011233}.
CC -!- SIMILARITY: Belongs to the fucolectin family.
CC {ECO:0000256|ARBA:ARBA00010147}.
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DR AlphaFoldDB; A0A3Q1JIY8; -.
DR Ensembl; ENSATET00000035614.2; ENSATEP00000035107.2; ENSATEG00000024120.2.
DR GeneTree; ENSGT01060000248575; -.
DR Proteomes; UP000265040; Unplaced.
DR GO; GO:0042806; F:fucose binding; IEA:UniProt.
DR GO; GO:0010185; P:regulation of cellular defense response; IEA:UniProt.
DR GO; GO:0001868; P:regulation of complement activation, lectin pathway; IEA:UniProt.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR InterPro; IPR000421; FA58C.
DR InterPro; IPR006585; FTP1.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR PANTHER; PTHR45713; FTP DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45713:SF8; V-FBPL-RELATED; 1.
DR Pfam; PF00754; F5_F8_type_C; 2.
DR SMART; SM00607; FTP; 2.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 2.
DR PROSITE; PS50022; FA58C_3; 1.
PE 3: Inferred from homology;
KW Lectin {ECO:0000256|ARBA:ARBA00022734};
KW Reference proteome {ECO:0000313|Proteomes:UP000265040}.
FT DOMAIN 135..289
FT /note="F5/8 type C"
FT /evidence="ECO:0000259|PROSITE:PS50022"
SQ SEQUENCE 311 AA; 34146 MW; 1947B094B2FDF8CD CRC64;
VITNIARGGK VTQSSLYGDA IPERAIDGNR ASNWGENSCT HTQNQLNPWW RLDLLNKYYI
NTVTITNRKD CCPERINGAE IRIGNSLTDY GNTNPICTVI SSIPAGTSTT YDCKGMEGQY
INIVIPGRQE YLTLCEVEVT GQLTGKTPSA NIARGGKVTQ SSLYGDAIPE RAIDGNRASN
WAENSCTHTQ NDMSPWWRVD LLKTYSINTV TITNRKDCCP ERINGAEIRI GNSLTDYGNT
NPICTVISSI PAGTSTTYNC KGMEGQYINI VIPGRQEYLT LCEVEVTGQL TGKTPSAELS
HLKCPVLNSY R
//
