ID   A0A3Q1JP87_ANATE        Unreviewed;       487 AA.
AC   A0A3Q1JP87;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   02-JUN-2021, sequence version 2.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=Fascin {ECO:0000256|PIRNR:PIRNR005682};
OS   Anabas testudineus (Climbing perch) (Anthias testudineus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Anabantaria; Anabantiformes; Anabantoidei; Anabantidae; Anabas.
OX   NCBI_TaxID=64144 {ECO:0000313|Ensembl:ENSATEP00000035170.2, ECO:0000313|Proteomes:UP000265040};
RN   [1] {ECO:0000313|Ensembl:ENSATEP00000035170.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC       {ECO:0000256|ARBA:ARBA00004245, ECO:0000256|PIRNR:PIRNR005682}.
CC   -!- SIMILARITY: Belongs to the fascin family.
CC       {ECO:0000256|ARBA:ARBA00007415, ECO:0000256|PIRNR:PIRNR005682}.
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DR   AlphaFoldDB; A0A3Q1JP87; -.
DR   STRING; 64144.ENSATEP00000035170; -.
DR   Ensembl; ENSATET00000035678.2; ENSATEP00000035170.2; ENSATEG00000024171.2.
DR   GeneTree; ENSGT00950000183157; -.
DR   InParanoid; A0A3Q1JP87; -.
DR   Proteomes; UP000265040; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR   GO; GO:0030674; F:protein-macromolecule adaptor activity; IEA:InterPro.
DR   GO; GO:0007015; P:actin filament organization; IEA:InterPro.
DR   CDD; cd00257; Fascin; 4.
DR   Gene3D; 2.80.10.50; -; 4.
DR   InterPro; IPR008999; Actin-crosslinking.
DR   InterPro; IPR010431; Fascin.
DR   InterPro; IPR022768; Fascin-domain.
DR   InterPro; IPR024703; Fascin_metazoans.
DR   PANTHER; PTHR10551; FASCIN; 1.
DR   PANTHER; PTHR10551:SF24; FASCIN-2; 1.
DR   Pfam; PF06268; Fascin; 4.
DR   PIRSF; PIRSF005682; Fascin; 1.
DR   SUPFAM; SSF50405; Actin-crosslinking proteins; 3.
PE   3: Inferred from homology;
KW   Actin-binding {ECO:0000256|ARBA:ARBA00023203,
KW   ECO:0000256|PIRNR:PIRNR005682};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|PIRNR:PIRNR005682};
KW   Cytoskeleton {ECO:0000256|ARBA:ARBA00023212,
KW   ECO:0000256|PIRNR:PIRNR005682};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265040}.
FT   DOMAIN          21..132
FT                   /note="Fascin"
FT                   /evidence="ECO:0000259|Pfam:PF06268"
FT   DOMAIN          143..253
FT                   /note="Fascin"
FT                   /evidence="ECO:0000259|Pfam:PF06268"
FT   DOMAIN          270..370
FT                   /note="Fascin"
FT                   /evidence="ECO:0000259|Pfam:PF06268"
FT   DOMAIN          385..487
FT                   /note="Fascin"
FT                   /evidence="ECO:0000259|Pfam:PF06268"
SQ   SEQUENCE   487 AA;  54386 MW;  882E7E0569C2401C CRC64;
     MPTNGINRAL KLQFGLINYE NRYLTAEGFG FKVNASGTSM KKKQIWTLEQ DEQDGQVVFL
     RSHLGRYLGS DKDGKITCAS EKPEPDCRFL IVAQSDGRWA LQSEPYLRYF GGSADYLSCF
     AQVIGEQELW AVHLALHPQA SLLSVARKRY AHLSASDGEI SVDSNIPWGV DSLVTLVYLE
     GKYSLKTCDN RFLSNDGKLV KENTNNTCFT LELKSGKLTF KDCDGKYLTP VGPTGTLRSG
     RCSKPGKDEL FDLEESHPQV VFQAANKRFV SVNISANQDV ETDMETFQME IDKENKKATF
     RTNGGSYWTL VTHGEIQSTA TEVEVNTMFD IEWREHRVAV KASNGKYVCT KKNGQLSAVS
     DSVADDELFL MKLINRPMLI LRGENGFVCH HKNSNTLDAN RSVYDIFSLI FNDGAYNIKS
     VNGKFWYISS SGLVCSDGEK PEEFFLEFLE HGRIAIKGSN GKYLRGDQGG TLMGDGSSVD
     ASSLWEY
//