ID A0A3Q1JPU4_ANATE Unreviewed; 1121 AA.
AC A0A3Q1JPU4;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012251};
DE EC=2.3.2.31 {ECO:0000256|ARBA:ARBA00012251};
OS Anabas testudineus (Climbing perch) (Anthias testudineus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Anabantaria; Anabantiformes; Anabantoidei; Anabantidae; Anabas.
OX NCBI_TaxID=64144 {ECO:0000313|Ensembl:ENSATEP00000035365.1, ECO:0000313|Proteomes:UP000265040};
RN [1] {ECO:0000313|Ensembl:ENSATEP00000035365.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.;
CC EC=2.3.2.31; Evidence={ECO:0000256|ARBA:ARBA00001798};
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DR AlphaFoldDB; A0A3Q1JPU4; -.
DR STRING; 64144.ENSATEP00000035365; -.
DR Ensembl; ENSATET00000035875.2; ENSATEP00000035365.1; ENSATEG00000024313.2.
DR GeneTree; ENSGT00940000157621; -.
DR InParanoid; A0A3Q1JPU4; -.
DR OMA; CNPENCC; -.
DR OrthoDB; 3084186at2759; -.
DR Proteomes; UP000265040; Unplaced.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
DR CDD; cd20346; BRcat_RBR_ANKIB1; 1.
DR CDD; cd20361; Rcat_RBR_ANKIB1; 1.
DR CDD; cd16774; RING-HC_RBR_ANKIB1; 1.
DR Gene3D; 1.20.120.1750; -; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR045840; Ariadne.
DR InterPro; IPR031127; E3_UB_ligase_RBR.
DR InterPro; IPR002867; IBR_dom.
DR InterPro; IPR047564; Rcat_RBR_ANKIB1.
DR InterPro; IPR047563; RING-HC_RBR_ANKIB1.
DR InterPro; IPR044066; TRIAD_supradom.
DR InterPro; IPR003903; UIM_dom.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR11685:SF465; ANKYRIN REPEAT AND IBR DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR11685; RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING; 1.
DR Pfam; PF00023; Ank; 2.
DR Pfam; PF19422; Ariadne; 1.
DR Pfam; PF01485; IBR; 2.
DR SMART; SM00248; ANK; 2.
DR SMART; SM00647; IBR; 2.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF57850; RING/U-box; 3.
DR PROSITE; PS50088; ANK_REPEAT; 2.
DR PROSITE; PS51873; TRIAD; 1.
DR PROSITE; PS50330; UIM; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000265040};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT REPEAT 45..78
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 145..177
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 330..570
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51873"
FT DOMAIN 334..380
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 775..813
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 572..633
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1121 AA; 125511 MW; 0E73565D8E02BB91 CRC64;
MGNTATKFRK ALINGDEVLA CQLYESNPQF KEALDPNSTY GESYQHNTPL HYAARHAMTR
LLRYFLLNKD GNPNKRNMHN ETSLHLLCMG PQILTSEGAL QPRISRPYED EQRRAECLQI
ILAWTGAKLD RGEYESADIN AVDNKKNTCL HYAAASGMRT CVELLVQREA DLFAENENRE
TPCDCAEKQH HKDLALCLES QMVFSLAPEA EGIEAEYAAL DRRELYEGLR PQDLRRLKDM
LIVETADMLQ SPLFTAEALL RAHDWDREKL LEAWMTNAEE CCQRSGVQMP HPPPSGCNAW
DTLPSPRTPR TTRSSITSPD QISLMPADEE SSLCGICMSS ISVFEEPVDM SCGHEFCRAC
WEGFLNLKIQ EGEAHNIFCP AFDCYQLVPV EVIESVVSKE MDRRYLQFDI KAFVENNPAI
RWCPEAGCER AVRLNAQGPG TSTSDPLSFP LLQAPAVDCG RGHLFCWECR GEAHEPCDCE
TWKMWLQKVT EMRPEELAGV SEAYEDAANC LWLLTNSKPC ANCKSPIQKN EGCNHMQCAK
CKYDFCWICL EEWKKHSSST GGYYRCTRYE VIQQVEEQSK EMTEEAEKKH KSFQELDRFM
HYYTRFKNHE HSYQLEQRLL KTAKEKMEQL SRALSGREGG PPDTTFIEDA VLELLKTRRI
LKCSYPYGFF LEPKSTKKEI YELMQTDLEM VTEDLAQKVN RPYLRTPRHK IIRAACLVQQ
KRQEFLASVA RGVAPNDSPE APRRSFAGGT WDWEYLGFAS PEEYAEFQYR RRHRQRRRGD
MSSLRSNTPD PDEPGENSLG TQDVRGGCRQ GPLMGLGSLD DDDPNILLAI QLSLQDSGMA
GGESNYESLA NEASLGAIGT SLPSRLEQRA PGVEVLPRAS LSSSELLELG DNLARLGNIN
SQYSAAAGVP ATGQHCDSHH RAYRPSVPIP VAPGGSNSST GLFSSSSDTL DSTICSTHDP
SSSSALAGNA NLLGNIMAWF HDMNPQGITL VPSNSSDTDS NFSALHADGG ERLQDDDKSS
VLVLPENRKP QEVMAEVGFC SHRLGDMEEK ECAVVERPTQ LDLVGLDTMP LPYMATADTS
GDHAEHGGSK VCHVDTPQCD SVFDQLPSTS SSEWEEQVHL V
//
