ID A0A3Q1JPZ7_ANATE Unreviewed; 586 AA.
AC A0A3Q1JPZ7;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Dihydropyrimidinase-related protein 2 {ECO:0000256|ARBA:ARBA00014316};
OS Anabas testudineus (Climbing perch) (Anthias testudineus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Anabantaria; Anabantiformes; Anabantoidei; Anabantidae; Anabas.
OX NCBI_TaxID=64144 {ECO:0000313|Ensembl:ENSATEP00000032918.1, ECO:0000313|Proteomes:UP000265040};
RN [1] {ECO:0000313|Ensembl:ENSATEP00000032918.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the metallo-dependent hydrolases superfamily.
CC Hydantoinase/dihydropyrimidinase family.
CC {ECO:0000256|ARBA:ARBA00008829}.
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DR AlphaFoldDB; A0A3Q1JPZ7; -.
DR STRING; 64144.ENSATEP00000032918; -.
DR Ensembl; ENSATET00000033397.2; ENSATEP00000032918.1; ENSATEG00000022665.2.
DR GeneTree; ENSGT01030000234527; -.
DR InParanoid; A0A3Q1JPZ7; -.
DR OMA; VTAFKQW; -.
DR OrthoDB; 1772494at2759; -.
DR Proteomes; UP000265040; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0016810; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; IEA:InterPro.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR CDD; cd01314; D-HYD; 1.
DR Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR Gene3D; 2.30.40.10; Urease, subunit C, domain 1; 1.
DR InterPro; IPR006680; Amidohydro-rel.
DR InterPro; IPR011778; Hydantoinase/dihydroPyrase.
DR InterPro; IPR011059; Metal-dep_hydrolase_composite.
DR InterPro; IPR032466; Metal_Hydrolase.
DR NCBIfam; TIGR02033; D-hydantoinase; 1.
DR PANTHER; PTHR11647:SF56; DIHYDROPYRIMIDINASE-RELATED PROTEIN 2; 1.
DR PANTHER; PTHR11647; HYDRANTOINASE/DIHYDROPYRIMIDINASE FAMILY MEMBER; 1.
DR Pfam; PF01979; Amidohydro_1; 1.
DR SUPFAM; SSF51338; Composite domain of metallo-dependent hydrolases; 2.
DR SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
PE 3: Inferred from homology;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW Neurogenesis {ECO:0000256|ARBA:ARBA00022902};
KW Reference proteome {ECO:0000313|Proteomes:UP000265040}.
FT DOMAIN 65..454
FT /note="Amidohydrolase-related"
FT /evidence="ECO:0000259|Pfam:PF01979"
FT REGION 516..542
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 555..586
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 586 AA; 64092 MW; 5C86791A0FA8673B CRC64;
MSGYQGKKNI PRITSDRLLI KGAKIVNDDQ SFLADIYMED GVIKQLGDNL IVPGGVKIIE
AHGRMVMPGG IDVHTRFQNP DRGMVAADDF YQGTRAALAG GTTTIIDHVV PEPGISLVAA
FKQWREWADS KSCCDYSLHV DITEWNKGTQ EEMETLVKDH GVNSFLVYLA YKDIFQLSDS
QIYEVFSVTR DLGAIAQVHA ENGDIIAEEQ QRILELGITG PEGHVLSRPE EVEAEAVNRA
ITIANQTNCP LYITKVMSKS AADVIALARK KGAVVYGEPI SASLGTDGTH YWSKNWAKAA
AYVTSPPLSP DPTTPDYLNS LLSCGDLQVT GSAHCTFLTS QRAVGKDNFT QIPEGTNGTE
ERMSLIWDKC VVSGKMDENQ FVAVTSTNAA KIFNLYPRKG RIAVGSDADL VLWDPDVTKI
ISAKSHNLAV EYNIFEGTEV RGGPLVVISQ GKIVLEEGSL HTTEGSGRYL SRKPFPDHVY
KRIKARSRLT ELRGVPRGQY DGPVCEVTVT PKLMSTVSSV KTSPAKQQQQ QQQQQQQQPF
THQPVRNLHQ SGFSLSGAQI DDNVPRRTTQ RIVAPPGGKA NITSLG
//
