ID A0A3Q1JVW6_ANATE Unreviewed; 796 AA.
AC A0A3Q1JVW6;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Rho GTPase activating protein 6 {ECO:0000313|Ensembl:ENSATEP00000019516.1};
GN Name=ARHGAP6 {ECO:0000313|Ensembl:ENSATEP00000019516.1};
OS Anabas testudineus (Climbing perch) (Anthias testudineus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Anabantaria; Anabantiformes; Anabantoidei; Anabantidae; Anabas.
OX NCBI_TaxID=64144 {ECO:0000313|Ensembl:ENSATEP00000019516.1, ECO:0000313|Proteomes:UP000265040};
RN [1] {ECO:0000313|Ensembl:ENSATEP00000019516.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3Q1JVW6; -.
DR STRING; 64144.ENSATEP00000019516; -.
DR Ensembl; ENSATET00000019843.2; ENSATEP00000019516.1; ENSATEG00000013542.2.
DR GeneTree; ENSGT00940000153904; -.
DR Proteomes; UP000265040; Unplaced.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd04376; RhoGAP_ARHGAP6; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR041852; ARHGAP6_RhoGAP.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR037863; RHOGAP6/36.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR12635:SF14; RHO GTPASE-ACTIVATING PROTEIN 6; 1.
DR PANTHER; PTHR12635; RHO-GTPASE-ACTIVATING PROTEIN 6 FAMILY MEMBER; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Reference proteome {ECO:0000313|Proteomes:UP000265040}.
FT DOMAIN 280..481
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 144..188
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 209..235
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 613..642
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 654..683
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 720..771
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 171..188
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 209..229
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 613..638
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 721..759
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 796 AA; 88719 MW; 28088F499E55B478 CRC64;
MSAQGLLSSV FSCSLSPKTL SKRRLRQTRS LDPALMRHYG TEAEETSYKV SELTASQGRW
VLFHEKRYLI CCMNNCLSVC PQDVSGGGVG PKPVPLQSLS ELERVRLQDV AFRRLLRDRD
LGCHITIPKC GHKHKKLLRR KLDSLSKEKN KDKETTPQVF GIPLSQVISN DRTHKQRHDA
QREEHSDPTE LMLSFLRLTS NVKRANKEFS SSTSSLSSTS ETPNESALPG TAPRTCRRGG
VSVDCITDLD DNQSRLLEAL QLSLPDEAAC NRKKHPDKKL SLNPIYRQVP RIVDLCCQHL
EKHGLETVGI FRVGSSKKRV RQLREEFDQG WDVHFDEENS VHDVAALLKE FLRDLPDPLL
TRELYTAFIN TMLLDYSDQA SAIQLLIFLL PPCNSDTLQR LLCLLSTVAK HAGDKLDNDG
QKITGNKMTS LNLATIFGPN LLHKQKNSDK EFSVQSFARV EDSTAIISVV QRMINTRDTL
FMVPTDLQNE VLMSLLETDP DVVDFLLRRK ASQCSDPSLL GTEESFALDG RCLSNDSIKA
SSGEVSPYDN NSPILSDGLL CKYGEDNSPL SERLSRLSEQ YKLSESTSPK DQVCDTDNFW
DTWHELFSMD FTSSPGDVSE SESYGSTEGL SSHHGNNKLP VRPTAPLLDV LECRPHPPVA
RSNSGPHDQR GQRRPESSLH QGLNDQSAAI SLDSLTERTG HPVCPLLNVS MDRLSPLPFS
GSLRETHNSH STPSLVSCQS DPQTLQSPTH QTVDPADSSG LGQGKSPGRA DWQTEKLHIW
RILSKENAEA MPESLV
//
