ID A0A3Q1JXV8_ANATE Unreviewed; 571 AA.
AC A0A3Q1JXV8;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=CBFA2/RUNX1 partner transcriptional co-repressor 2 {ECO:0000313|Ensembl:ENSATEP00000036459.2};
OS Anabas testudineus (Climbing perch) (Anthias testudineus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Anabantaria; Anabantiformes; Anabantoidei; Anabantidae; Anabas.
OX NCBI_TaxID=64144 {ECO:0000313|Ensembl:ENSATEP00000036459.2, ECO:0000313|Proteomes:UP000265040};
RN [1] {ECO:0000313|Ensembl:ENSATEP00000036459.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3Q1JXV8; -.
DR STRING; 64144.ENSATEP00000036459; -.
DR Ensembl; ENSATET00000036979.2; ENSATEP00000036459.2; ENSATEG00000025051.2.
DR GeneTree; ENSGT00950000183176; -.
DR Proteomes; UP000265040; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003714; F:transcription corepressor activity; IEA:InterPro.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR Gene3D; 6.10.140.2220; -; 1.
DR Gene3D; 6.10.250.230; -; 1.
DR Gene3D; 1.20.120.1110; TAFH/NHR1 domain; 1.
DR InterPro; IPR013289; CBFA2T1/2/3.
DR InterPro; IPR014896; NHR2.
DR InterPro; IPR037249; TAFH/NHR1_dom_sf.
DR InterPro; IPR003894; TAFH_NHR1.
DR InterPro; IPR002893; Znf_MYND.
DR PANTHER; PTHR10379; MTG8 ETO EIGHT TWENTY ONE PROTEIN; 1.
DR PANTHER; PTHR10379:SF13; PROTEIN CBFA2T2; 1.
DR Pfam; PF08788; NHR2; 1.
DR Pfam; PF07531; TAFH; 1.
DR Pfam; PF01753; zf-MYND; 1.
DR PRINTS; PR01875; ETOFAMILY.
DR SMART; SM00549; TAFH; 1.
DR SUPFAM; SSF144232; HIT/MYND zinc finger-like; 1.
DR SUPFAM; SSF158553; TAFH domain-like; 1.
DR PROSITE; PS51119; TAFH; 1.
DR PROSITE; PS50865; ZF_MYND_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000265040};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00134}.
FT DOMAIN 106..201
FT /note="TAFH"
FT /evidence="ECO:0000259|PROSITE:PS51119"
FT DOMAIN 500..536
FT /note="MYND-type"
FT /evidence="ECO:0000259|PROSITE:PS50865"
FT REGION 1..95
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 213..241
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 380..422
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 439..486
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 16..33
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 40..95
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 223..241
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 571 AA; 63987 MW; C8C9D92EDB38436A CRC64;
EKKSPAMPGS PVDAKTHSRS APSSSASSTM PPLPSVNPSG PRPASFSTTA SCHIRSRLST
PVTNGNHHSP PTLNAVPSPP QRYSNGPSSS FSSSLANQQL PATCGARQLS KLKRFLTTLQ
QFGNDISPEI GDSVRSLVLA LVNSTVTIEE FHSRLQEATN FPLRPFVIPF LKANLPLLQR
ELLHCARAAK QTPAQYLSQH EHLLLSTTLA SSPDSSELLM EPPDAGTKRH SPSRAKENGF
HERPPIAMEP AAKRICTISP APRHSPAHPL PLNAQLHPTP PPLQHYALDD IAAPHILHRE
HSQRMLEIRE LKDRPRLPGT NGGYREEPVD HRLTDREWAD EWRHLDHVLN CIVDMVEKTR
RSVSALRRCQ ESDREELNYW RRRSNEQEDP RKGGSGITPF SKTHSPHTAE SESQRDFAPR
PGSAYVTDEI WRKAEEAVNE VKRQAMDEVQ KAVAEAEQKA FEMIAAERAK MEKTLAEAKR
KAQEDAIMVI NEQEDSSECC WNCGRKASET CSGCNAARYC GSFCQHKDWE RHHLICSPGL
QAQNYVWVKL GEQIFHHNIW QIKKGRLWMT V
//
