ID A0A3Q1KCW0_ANATE Unreviewed; 457 AA.
AC A0A3Q1KCW0;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=HtrA serine peptidase 3a {ECO:0000313|Ensembl:ENSATEP00000032466.2};
OS Anabas testudineus (Climbing perch) (Anthias testudineus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Anabantaria; Anabantiformes; Anabantoidei; Anabantidae; Anabas.
OX NCBI_TaxID=64144 {ECO:0000313|Ensembl:ENSATEP00000032466.2, ECO:0000313|Proteomes:UP000265040};
RN [1] {ECO:0000313|Ensembl:ENSATEP00000032466.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the peptidase S1C family.
CC {ECO:0000256|ARBA:ARBA00010541}.
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DR AlphaFoldDB; A0A3Q1KCW0; -.
DR STRING; 64144.ENSATEP00000032466; -.
DR Ensembl; ENSATET00000032941.2; ENSATEP00000032466.2; ENSATEG00000022357.2.
DR GeneTree; ENSGT00940000159570; -.
DR Proteomes; UP000265040; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR CDD; cd00104; KAZAL_FS; 1.
DR CDD; cd00987; PDZ_serine_protease; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 2.40.10.120; -; 1.
DR Gene3D; 3.30.60.30; -; 1.
DR Gene3D; 4.10.40.20; -; 1.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR000867; IGFBP-like.
DR InterPro; IPR002350; Kazal_dom.
DR InterPro; IPR041489; PDZ_6.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR001940; Peptidase_S1C.
DR PANTHER; PTHR22939; SERINE PROTEASE FAMILY S1C HTRA-RELATED; 1.
DR PANTHER; PTHR22939:SF14; SERINE PROTEASE HTRA3; 1.
DR Pfam; PF00219; IGFBP; 1.
DR Pfam; PF07648; Kazal_2; 1.
DR Pfam; PF17820; PDZ_6; 1.
DR Pfam; PF13365; Trypsin_2; 1.
DR PRINTS; PR00834; PROTEASES2C.
DR SMART; SM00121; IB; 1.
DR SMART; SM00280; KAZAL; 1.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS51323; IGFBP_N_2; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Reference proteome {ECO:0000313|Proteomes:UP000265040};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..457
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5030080747"
FT DOMAIN 27..100
FT /note="IGFBP N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51323"
SQ SEQUENCE 457 AA; 49469 MW; AB3D2DD59EA3A51B CRC64;
MSTLTTPQLL LVALFFTHDL TGAGAVRSDQ CASRCDVSSC PTPSCPGGYV PDRCNCCLVC
SPREGDPCGR KNDLPCGAGL ECKPLAPGRR RGSKRVCRCK TEHEVCGSDG RTYGNVCRMR
AASRKARQTG RAAVSQAHKG RFLVNKGASM VHLSSPRYKF NFIADVVEKI APAVVHIELF
VRHPLFGRHM RLSSGSGFIV THSGVIVTNA HVVTPAATVT GRPQLRVQLH GGEAYGAVVR
DVDRRADIAT VKINQKKLPV LSLGRSADLR PGEFVVAIGS PFALQNTVTT GIVSTAQRDG
KELGIKDSDM DYIQTDAIIN YGNSGGPLVN LDGEVIGINT LKVTAGIAFA IPSDRISLFL
RCYLRNVQFH TAVYNRGYCT SVALRTCSNQ IADYCFLSLR LRGGIKKGDV IVKVNGDPVE
TTEDIHKALQ GDQPLLLEIH RGRDDLLFNI HPQVTLH
//
